alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,501–14,525 of 27,380 studies, newest first · page 581 of 1096.

December 2017 25

  1. 2017-12-19

    Optical Coherence Tomography in Alzheimer's Disease and Other Neurodegenerative Diseases

    ✓ Peer-reviewed Mild cognitive impairment Frontiers in neurology

    Key finding: Numerous studies have shown that the retina, a central nervous system tissue formed as a developmental outgrowth of the brain, is profoundly affected by AD.

    Full summary, score breakdown and related studies → Original source

  2. 2017-12-19

    Does Cognitive Training Prevent Cognitive Decline?: A Systematic Review

    ✓ Peer-reviewed Prevention and risk Annals of internal medicine

    Key finding: In older adults with normal cognition, training improves cognitive performance in the domain trained.

    Full summary, score breakdown and related studies → Original source

  3. 2017-12-19

    Physical Activity Interventions in Preventing Cognitive Decline and Alzheimer-Type Dementia: A Systematic Review

    ✓ Peer-reviewed Prevention and risk Annals of internal medicine

    Key finding: Evidence that short-term, single-component physical activity interventions promote cognitive function and prevent cognitive decline or dementia in older adults is largely insufficient. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2017-12-19

    Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease

    ✓ Peer-reviewed Treatments NeuroImage

    Key finding: We found that rTMS of the PC induced a selective improvement in episodic memory, but not in other cognitive domains. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-12-18

    Hearing aids: indications, technology, adaptation, and quality control

    ✓ Peer-reviewed Risk factors GMS current topics in otorhinolaryngology, head and neck surgery

    Key finding: Both the users' acceptance and the perceived sound quality were significantly increased by open fittings. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2017-12-16

    Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

    ✓ Peer-reviewed Genetics The Lancet. Neurology

    Key finding: In the replication stage, we performed genotyping of significant and suggestive results from the discovery stage. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2017-12-15

    Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice

    ✓ Peer-reviewed Drug development Brain, behavior, and immunity

    Key finding: Here we showed that metformin attenuated spatial memory deficit, neuron loss in the hippocampus and enhanced neurogenesis in APP/PS1 mice. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2017-12-15

    Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Plasma levels of Aβ oligomers could be assessed using MDS, which might be a simple, noninvasive, and accessible assay for evaluating brain amyloid deposition related to AD pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-12-15

    Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Dendritic spine structure is defined by filamentous actin (F-actin) and we observed depolymerization of synaptosomal F-actin accompanied by increased globular-actin (G-actin) at as early as 1 month of age in a mouse model of AD (APPswe/PS1ΔE9, male mice). +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2017-12-14

    Advance Care Planning in Community-Dwelling Patients With Dementia

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: Our findings support need for greater ACP discussions between patients and proxies. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2017-12-14

    Immunosenescence in aging: between immune cells depletion and cytokines up-regulation

    ✓ Peer-reviewed Risk factors Clinical and molecular allergy : CMA

    Key finding: The increase of pro-inflammatory cytokines is associated with dementia, Parkinson's disease, atherosclerosis, diabetes type 2, sarcopenia and a high risk of morbidity and mortality. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2017-12-13

    Blood-Brain Glucose Transfer in Alzheimer's disease: Effect of GLP-1 Analog Treatment

    ✓ Peer-reviewed Drug development Scientific reports

    Key finding: The GLP-1 analog treatment, compared to placebo, highly significantly raised the T max estimates of cerebral cortex from 0.72 to 1.1 umol/g/min, equal to T max estimates in healthy volunteers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2017-12-13

    Palliative care for advanced dementia: Knowledge and attitudes of long-term care staff

    ✓ Peer-reviewed End-of-life care Journal of clinical nursing

    Key finding: This study indicates the need to provide nurses and nursing assistants with more information about palliative care practice for people with advanced dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2017-12-13

    Needs of people with advanced dementia in their final phase of life: A multi-perspective qualitative study in nursing homes

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: People with advanced dementia in their final phase of life have a multitude of individual and complex needs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2017-12-13

    Risk factors for hospital death in conditions needing palliative care: Nationwide population-based death certificate study

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: The upward hospital death trend and fact that being married are risk factors for hospital death suggest that a reliance on hospitals may coexist with a tradition of extended family support. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2017-12-12

    Trace lithium and mental health

    ✓ Peer-reviewed Drug development Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: The results indicate that trace lithium may be effective for suicide prevention but randomized, placebo-controlled trials are required to draw a definite conclusion.

    Full summary, score breakdown and related studies → Original source

  17. 2017-12-12

    The Role of Inflammation in Age-Related Sarcopenia

    ✓ Peer-reviewed Prevention trials Frontiers in physiology

    Key finding: These changes often, directly or indirectly, result in a deterioration of the quality of life and even in a shortening of life expectancy.

    Full summary, score breakdown and related studies → Original source

  18. 2017-12-12

    Markers of microglia in post-mortem brain samples from patients with Alzheimer's disease: a systematic review

    ✓ Peer-reviewed Inflammation and the immune system Molecular psychiatry

    Key finding: Increases in the expression of markers of microglia, the main neuroinmmune cell, are widely reported in brains from patients with Alzheimer's disease, but the literature has not yet been systematically reviewed to determine whether this is a consistent pathological feature. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2017-12-12

    Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in neuroscience

    Key finding: Alzheimer's disease is the most common proteopathy and is characterized by two unique pathologies: senile plaques and neurofibrillary tangles, the former accumulating earlier than the latter. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2017-12-12

    Secular Trends in Dementia and Cognitive Impairment of U.S. Rural and Urban Older Adults

    ✓ Peer-reviewed Disparities American journal of preventive medicine

    Key finding: Larger gains in rural adults' cognitive functioning between 2000 and 2010 that are linked with increased educational attainment demonstrate long-term public health benefits of investment in secondary education. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2017-12-11

    Facilitating Imagine Arts in residential care homes: the artists' perspectives

    ✓ Peer-reviewed Health systems and care delivery Arts & health

    Key finding: Data were analysed using thematic analysis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2017-12-11

    Nuclear Factor-Kappa B and Alzheimer Disease, Unifying Genetic and Environmental Risk Factors from Cell to Humans

    ✓ Peer-reviewed Treatments Frontiers in immunology

    Key finding: There are a number of risk factors associated with developing AD but the exact cause remains unknown.

    Full summary, score breakdown and related studies → Original source

  23. 2017-12-11

    Age-Related Diseases and Clinical and Public Health Implications for the 85 Years Old and Over Population

    ✓ Peer-reviewed Caregiving Frontiers in public health

    Key finding: Osteoarthritis, diabetes, and related mobility disability will increase in prevalence as the population ages and becomes more overweight. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2017-12-11

    Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: Regional binding of 3 H-THK5117 and 3 H-THK5351 was similar, except in the temporal cortex, which showed higher 3 H-THK5117 binding. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2017-12-09

    Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

    ✓ Peer-reviewed Disease mechanisms Pharmacological research

    Key finding: Clinical studies have shown that, in cognitively impaired elderly patients with brain amyloidosis, there is lower abundance in the gut of E. rectale and B. fragilis, two bacterial species which have an anti-inflammatory activity, versus a greater amount of pro-inflammatory genera such as Escherichia/Shigella. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →