Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 13,276–13,300 of 27,380 studies, newest first · page 532 of 1096.
January 2019 25
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2019 year only
Palliative medicine and end-of-life care
39/100 ✓ Peer-reviewed End-of-life care Handbook of clinical neurology
Key finding: Patients and families affected by a neurodegenerative illness have significant palliative care needs beginning at the time of diagnosis and extending through end-of-life care and bereavement.
Full summary, score breakdown and related studies → Original source
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2019-01 month only
Risk of caregiver burden in patients with three types of dementia
39/100 ✓ Peer-reviewed Caregiving International psychogeriatrics
Key finding: (2017) investigated caregiver burden of patients with frontotemporal lobar degeneration (FTD) and dementia with Lewy bodies (DLB), which was compared with caregivers of patients with Alzheimer's disease. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
Noradrenergic Regulation of Hippocampus-Dependent Memory
39/100 ✓ Peer-reviewed Disease mechanisms Central nervous system agents in medicinal chemistry
Key finding: Changes in synaptic strength are widely considered to be a cellular representation of learned information. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Cerebral Microbleeds Are Associated with Cerebral Hypoperfusion in Patients with Alzheimer's Disease
39/100 ✓ Peer-reviewed Vascular contributions Journal of Alzheimer's disease : JAD
Key finding: The number of microbleeds was significantly correlated with the severity of decrease in the occipital lobe (Spearman's r = 0.531, p < 0.001) and temporal lobe (r = 0.437, p < 0.001) but not in the frontal lobe (r = 0.201, p = 0.101) and parietal lobe (r = 0.178, p = 0.146). +3 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Pericytes in Alzheimer's Disease: Novel Clues to Cerebral Amyloid Angiopathy Pathogenesis
39/100 ✓ Peer-reviewed Vascular contributions Advances in experimental medicine and biology
Key finding: Pericytes in the central nervous system attract growing attention of neurobiologists because of obvious opportunities to use them as target cells in numerous brain diseases. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Endothelial Mitochondrial Dysfunction in Cerebral Amyloid Angiopathy and Alzheimer's Disease
39/100 ✓ Peer-reviewed Vascular contributions Journal of Alzheimer's disease : JAD
Key finding: Mitochondrial dysfunction is increasingly recognized as an important early initiator of the pathogenesis of AD and CAA. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Neurovascular Ageing and Age-Related Diseases
39/100 ✓ Peer-reviewed Vascular contributions Sub-cellular biochemistry
Key finding: Ultimately, the integrity of both the neurovascular and gliovascular units is compromised such that there is an overall synergistic effect reflecting on ageing associated cerebral perfusion and permeability. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia
39/100 ✓ Peer-reviewed Vascular contributions ASN neuro
Key finding: Blood flow deficits and barrier permeability changes occurred alongside changes in memory and in genes associated with metabolism, endothelial nitric oxide signaling, barrier integrity, and extracellular matrix remodeling. +2 more findings
Full summary, score breakdown and related studies → Original source
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2019-01 month only
The intestinal microbiome and its relevance for functionality in older persons
39/100 ✓ Peer-reviewed Disease mechanisms Current opinion in clinical nutrition and metabolic care
Key finding: Some observational studies have instead demonstrated that, in older individuals, frailty and Alzheimer-type dementia are associated with fecal microbiota dysbiosis, that is, reduced biodiversity and overexpression of pathobionts. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
Stavudine Reduces NLRP3 Inflammasome Activation and Modulates Amyloid-β Autophagy
39/100 ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD
Key finding: IL-1β, IL-18, and caspase-1 were increased whereas Aβ phagocytosis and TREM2 were reduced in LPS+Aβ42-stimulated cells. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Mild Cognitive Impairment and Dementia Involving Multiple Cognitive Domains in Mexican Urbanites
43/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: Exposures to fine particulate matter PM2.5 and ozone O3 are associated with Alzheimer's disease (AD) risk. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
Fine Particulate Matter Exposure and Cerebrospinal Fluid Markers of Vascular Injury
39/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: Among cognitively normal individuals, a 5 μg/m3 increase in 7-day and 1-year average PM2.5 was associated with elevated VCAM-1 (7-day: 35.4 (9.7, 61.1) ng/ml; 1-year: 51.8 (6.5, 97.1) ng/ml). +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Dementia Around the World and the Latin America and Mexican Scenarios
39/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: Dementia risk factors are significantly different among countries. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life
39/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: Midlife cognition was significantly associated with late-life cognition, but not with late-life elevated SUVR; education was not associated with late-life SUVR, but was strongly associated with late-life cognition.
Full summary, score breakdown and related studies → Original source
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2019 year only
Bilingualism and Dementia: Cognitive Reserve to Linguistic Competency
39/100 ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD
Key finding: Despite the large number of elderly bilinguals at risk for Alzheimer's disease (AD) and dementia worldwide, significant questions remain about the relationship between speaking more than one language and later cognitive decline. +2 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Cognitive reserve and dementia A scientometric review
39/100 ✓ Peer-reviewed Risk factors Dementia & neuropsychologia
Key finding: The results revealed that author Stern Y had the highest number of publications and citations.
Full summary, score breakdown and related studies → Original source
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2019 year only
Therapeutic Approaches to Alzheimer's Type of Dementia: A Focus on FGF21 Mediated Neuroprotection
39/100 ✓ Peer-reviewed Risk factors Current pharmaceutical design
Key finding: With the identification of insulin and insulin receptors in some parts of the brain, it has become evident that certain metabolic conditions associated with insulin dysfunction like Type 2 diabetes mellitus (T2DM), dyslipidemia, obesity etc., are also known to contribute to neurodegeneration mainly Alzheimer's Disease (AD).
Full summary, score breakdown and related studies → Original source
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2019 year only
[Presbyacusis]
39/100 ✓ Peer-reviewed Risk factors Vestnik otorinolaringologii
Key finding: Age-related hearing loss is the result of the biological process of aging of the tissue elements of the auditory analyzer. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
Role of Obstructive Sleep Apnea in Cognitive Impairment
39/100 ✓ Peer-reviewed Risk factors International journal of head and neck surgery
Key finding: Emerging science suggest that untreated and undertreated OSA increases the risk of developing cognitive impairment, including vascular dementia and neurodegenerative disorders, like Alzheimer's disease. +1 more finding
Full summary, score breakdown and related studies → Original source
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2019 year only
[Sleep and cognitive impairment in neurodegenerative diseases]
39/100 ✓ Peer-reviewed Risk factors Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Key finding: Sleep and wakefulness disorders are commonly seen in patients with Parkinson's disease, Lewy body dementia and Alzheimer's disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Sleep physiology and disorders in aging and dementia
39/100 ✓ Peer-reviewed Risk factors Handbook of clinical neurology
Key finding: Sleep problems occur commonly in normal and pathologic aging. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
Systematic Multi-Domain Alzheimer's Risk Reduction Trial (SMARRT): Study Protocol
48/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: Randomization will be stratified by clinic, race/ethnicity (non-Hispanic white versus non-white or Hispanic), and age (70-79, 80-89).
Full summary, score breakdown and related studies → Original source
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2019 year only
A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Assessing Safety, Tolerability, and Efficacy of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease
75/100 ✓ Peer-reviewed Clinical trials Journal of Alzheimer's disease : JAD
Key finding: The safety profile was similar for 20 μg treatment and placebo patients. +4 more findings
Full summary, score breakdown and related studies → Original source
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2019 year only
A Review for Lithium: Pharmacokinetics, Drug Design, and Toxicity
39/100 ✓ Peer-reviewed Drug development CNS & neurological disorders drug targets
Key finding: Recent studies have also shown that it has the potential for the treatment of many other neurodegenerative disorders, including Alzheimer's, Parkinson's and Huntington's disease, through its neurotrophic, neuroprotective, antioxidant and anti-inflammatory actions.
Full summary, score breakdown and related studies → Original source
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2019 year only
Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning
39/100 ✓ Peer-reviewed Treatments Current pharmaceutical design
Key finding: The treatment approach of inhibiting peripheral AChE for myasthenia gravis had effectively proven that AChE inhibition was a reachable therapeutic target. +4 more findings
Full summary, score breakdown and related studies → Original source
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