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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26889 of the 27780 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,226–13,250 of 27,780 studies, newest first · page 530 of 1112.

March 2019 25

  1. 2019-03-17

    The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial

    ✓ Peer-reviewed Prevention trials Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Computerized cognitive training significantly improved global cognitive function, which was supported by the improved brain plasticity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-03-17

    RETRACTED: Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

    ⚠ Retracted — do not rely on it Biomarkers Nutrients

    Key finding: Glial activation and neuroinflammation play significant roles in apoptosis as well as in the development of cognitive and memory deficits. +2 more findings

    Scored 28 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  3. 2019-03-16

    Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer's disease pathogenesis

    ✓ Peer-reviewed Disease mechanisms Neuroscience letters

    Key finding: Several lines of evidence have shown that defects in the endo-lysosomal autophagy degradation pathway and the ubiquitin-proteasome system play a role in Alzheimer's Disease (AD) pathogenesis and pathophysiology. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2019-03-15

    The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity

    ✓ Peer-reviewed Genetics Genes

    Key finding: Genome-wide association (GWAS) and whole-genome sequencing (WGS) studies on centenarians pointed toward the inclusion of the apolipoprotein E (APOE) polymorphisms ε2 and ε4, as implicated in the attainment of extreme longevity, which refers to their effect in age-related Alzheimer's disease (AD) and cardiovascular disease (CVD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-03-15

    The Therapeutic Potential of Apigenin

    ✓ Peer-reviewed Risk factors International journal of molecular sciences

    Key finding: The present work is an updated overview of apigenin, focusing on its health-promoting effects/therapeutic functions and, in particular, results of in vivo research.

    Full summary, score breakdown and related studies → Original source

  6. 2019-03-15

    Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

    ✓ Peer-reviewed Drug development Scientific reports

    Key finding: We further demonstrate that microglia activation alone is not sufficient to induce significant tau clearance.

    Full summary, score breakdown and related studies → Original source

  7. 2019-03-15

    Effect of Off-Target Binding on 18F-Flortaucipir Variability in Healthy Controls Across the Life Span

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: The correlation between white and gray matter disappeared after partial-volume correction in 11 C-PIB ( r 2 = 0) but persisted for 18 F-flortaucipir ( r 2 = 0.27), demonstrating that the correlation between white and gray matter signal in 18 F-flortaucipir is not solely due to partial-volume effects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-03-14

    Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

    ✓ Peer-reviewed How common it is The Lancet. Neurology

    Key finding: For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05-1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7.

    Full summary, score breakdown and related studies → Original source

  9. 2019-03-14

    Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition

    ✓ Peer-reviewed Inflammation and the immune system Cell

    Key finding: Whole brain analysis using SHIELD revealed widespread reduction of amyloid plaques throughout neocortex after multi-sensory GENUS.

    Full summary, score breakdown and related studies → Original source

  10. 2019-03-14

    Global Evolution of Research in Artificial Intelligence in Health and Medicine: A Bibliometric Study

    ✓ Peer-reviewed Risk factors Journal of clinical medicine

    Key finding: The descriptive analysis examined the publication volume, and authors and countries collaboration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-03-13

    Medicare expenditures attributable to dementia

    ✓ Peer-reviewed Costs and economics Health services research

    Key finding: Dementia's five-year incremental cost to the traditional Medicare program is approximately $15 700 per patient, nearly half of which is incurred in the first year after diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-03-13

    Attention network dysfunction underlies memory impairment in posterior cortical atrophy

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: Accumulating evidence suggests that memory is impaired in posterior cortical atrophy (PCA), alongside the early and defining visual disorder. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-03-13

    Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife

    ✓ Peer-reviewed Prevention trials The Cochrane database of systematic reviews

    Key finding: Low cognitive and brain reserve and limited cognitive stimulation are associated with increased risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-03-13

    Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life

    ✓ Peer-reviewed Prevention trials The Cochrane database of systematic reviews

    Key finding: We found no studies on our primary outcome of global cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-03-13

    Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid- and 18F-FDG-PET imaging

    ✓ Peer-reviewed Cognitive tests and assessment NeuroImage. Clinical

    Key finding: Therefore, it is of great interest to determine which biomarkers should be combined to accurately predict conversion from mild cognitive impairment (MCI) to AD dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-03-13

    Computerised cognitive training for preventing dementia in people with mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment The Cochrane database of systematic reviews

    Key finding: Selection criteria We included randomised controlled trials (RCTs) and quasi-RCTs in which cognitive training via interactive computerised technology was compared with an active or inactive control intervention. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-03-13

    Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging NeuroImage. Clinical

    Key finding: Interest in understanding the roles of white matter (WM) inflammation and damage in the pathophysiology of Alzheimer disease (AD) has been growing significantly in recent years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-03-13

    Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment

    ✓ Peer-reviewed Prevention and risk The Journal of steroid biochemistry and molecular biology

    Key finding: High level of serum cholesterol has been found to positively correlate with an increased risk of dementia and some studies have reported a decreased prevalence of AD in patients taking cholesterol-lowering drugs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2019-03-12

    Aβ and tau structure-based biomarkers for a blood- and CSF-based two-step recruitment strategy to identify patients with dementia due to Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The primary Aβ-based blood biomarker funnels individuals with suspected AD for subsequent validation of the diagnosis by structure-based combined analysis of the CSF biomarkers Aβ and tau. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2019-03-12

    Signs and Symptoms of Low-Intake Dehydration Do Not Work in Older Care Home Residents-DRIE Diagnostic Accuracy Study

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: This study consolidates evidence that commonly used signs and symptoms of dehydration lack even basic levels of diagnostic accuracy in older adults, implying that many who are dehydrated are not being identified, thus compromising their health and well-being. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-03-12

    Strengths and support of older people affected by precarity in South Louisiana

    ✓ Peer-reviewed Risk factors International Journal of Older People Nursing

    Key finding: The findings demonstrate five central negative conditions of precarity that older people had to manage: (a) loss and discontinuity of home-based healthcare services, (b) stress after loss or disruption of social support, (c) problems of poverty, (d) cognitive impairment and declining health and (e) stress of eviction. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-03-12

    Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine

    ✓ Peer-reviewed Prevention and risk Pharmacology & therapeutics

    Key finding: Risk factors for AD including aging, the female sex, as well as carrying an APOE4 genotype. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-03-11

    Dementia and Parkinson's Disease: Similar and Divergent Challenges in Providing Palliative Care

    ✓ Peer-reviewed End-of-life care Frontiers in neurology

    Key finding: However, for both conditions, the protracted disease trajectories complicate conceptualization of palliative care through different stages of the disease, with pertinent questions such as when to offer what interventions pro-actively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-03-11

    Retinal Microvascular and Neurodegenerative Changes in Alzheimer's Disease and Mild Cognitive Impairment Compared with Control Participants

    ✓ Peer-reviewed Brain scans and imaging Ophthalmology. Retina

    Key finding: Alzheimer's participants showed significantly reduced macular VD, PD, and GC-IPL thickness compared with MCI and controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-03-11

    Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue

    ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications

    Key finding: Our data indicate that MK-6240 strongly binds to neurofibrillary tangles in Alzheimer disease but does not seem to bind to a significant extent to tau aggregates in non-Alzheimer tauopathies, suggesting that it may have a limited utility for the in vivo detection of these pathologies. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →