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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26889 of the 27780 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,001–13,025 of 27,780 studies, newest first · page 521 of 1112.

June 2019 7

  1. 2019-06-01

    Obstructive sleep apnea and longitudinal Alzheimer's disease biomarker changes

    ✓ Peer-reviewed Mild cognitive impairment Sleep

    Key finding: Study objectives To determine the effect of self-reported clinical diagnosis of obstructive sleep apnea (OSA) on longitudinal changes in brain amyloid PET and CSF biomarkers (Aβ42, T-tau, and P-tau) in cognitively normal (NL), mild cognitive impairment (MCI), and Alzheimer's disease (AD) elderly. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2019-06-01

    A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer's disease dementia

    ✓ Peer-reviewed Caregiving Brain : a journal of neurology

    Key finding: There was a statistically significant increase in the global estimate of cortical tau burden as measured by standardized uptake value ratio (SUVr) from baseline to 18 months in amyloid-β+ but not amyloid-β- subjects (least squared mean change in flortaucipir SUVr : 0.0524 ± 0.0085, P < 0.0001 and 0.0007 ± 0.0024 P = 0.7850, respectively), and a significant association between magnitude of SUVr increase and baseline tau burden. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-06-01

    Physical Activity, Cognition, and Brain Outcomes: A Review of the 2018 Physical Activity Guidelines

    ✓ Peer-reviewed Prevention and risk Medicine and science in sports and exercise

    Key finding: There is moderate-to-strong support that PA benefits cognitive functioning during early and late periods of the life span and in certain populations characterized by cognitive deficits. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-06-01

    Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

    ✓ Peer-reviewed Prevention and risk Brain : a journal of neurology

    Key finding: LATE-NC is a common TDP-43 proteinopathy, associated with an amnestic dementia syndrome that mimicked Alzheimer's-type dementia in retrospective autopsy studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-06-01

    CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study

    ✓ Peer-reviewed Genetics Annals of surgery

    Key finding: Delirium following surgery is common and associated with adverse outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2019-06-01

    Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Estimates of AD disease duration become more accurate if age, sex, setting, APOE, and cerebrospinal fluid tau are taken into account. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2019-06-01

    Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

    ✓ Peer-reviewed Biomarkers JAMA

    Key finding: Analyses measured the associations between predictor variables and the memory score, and whether AT(N) biomarker profiles significantly improved prediction of memory z score rates of change beyond a model with clinical and genetic variables only. +2 more findings

    Full summary, score breakdown and related studies → Original source

May 2019 18

  1. 2019-05-31

    Association Between Relevant Co-Morbidities and Dementia With Atrial Fibrillation-A National Study

    ✓ Peer-reviewed Risk factors Archives of medical research

    Key finding: Totally 30,332 patients (5.6%) were diagnosed with dementia during the follow-up, with 14,097 men (4.9%) and 16,235 women (6.5%). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-05-31

    Diagnosis of Alzheimer's Disease via Multi-Modality 3D Convolutional Neural Network

    ✓ Peer-reviewed Digital health tools Frontiers in neuroscience

    Key finding: Finally, the results have demonstrated that (1) segmentation is not a prerequisite when using a CNN for the classification, (2) the combination of two modality imaging data generates better results.

    Full summary, score breakdown and related studies → Original source

  3. 2019-05-31

    Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: Numerous population-based studies have suggested that early-life educational attainments and socioeconomic status, midlife work complexity and social engagements, late-life leisure activities (social, physical, and mentally-stimulating activities), certain personality traits (e.g., high neuroticism and low conscientiousness), and depression significantly affect late-life cognitive phenotypes.

    Full summary, score breakdown and related studies → Original source

  4. 2019-05-30

    Caregiver preparedness for death in dementia: an evaluation of existing tools

    ✓ Peer-reviewed End-of-life care Aging & mental health

    Key finding: Authors extracted 569 tools from articles, retaining seven tools for evaluation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-05-30

    Palliative Care in the Hip Fracture Patient

    ✓ Peer-reviewed End-of-life care Geriatric orthopaedic surgery & rehabilitation

    Key finding: Evaluation of each patient using a variety of decision making tools should help the orthopedic surgeon determine which patients would be better suited to non-operative management.

    Full summary, score breakdown and related studies → Original source

  6. 2019-05-30

    End-of-life experiences in dementia with Lewy bodies: Qualitative interviews with former caregivers

    ✓ Peer-reviewed End-of-life care PloS one

    Key finding: Study results emphasize the need for improved EOL counseling in DLB, recognition of EOL symptoms, earlier hospice involvement, tailoring EOL care to DLB-specific needs, and clinician-family communication. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2019-05-30

    Cognitive and neural plasticity in old age: A systematic review of evidence from executive functions cognitive training

    ✓ Peer-reviewed Prevention trials Ageing research reviews

    Key finding: This systematic review examined the effects of executive functions training on brain and cognition amongst healthy older adults across 20 studies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-05-30

    Vitamin D and the nervous system

    ✓ Peer-reviewed Brain scans and imaging Neurological research

    Key finding: the studies reviewed show that VD contributes to cerebral activity in both embryonic and adult brain, helping the connectivity of neural circuits responsible for locomotor, emotional and reward-dependent behavior. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-05-29

    Prevalence of idiopathic normal pressure hydrocephalus: A prospective, population-based study

    ✓ Peer-reviewed Digital health tools PloS one

    Key finding: In this prospective, population-based study the prevalence of iNPH was 3.7% among individuals 65 years and older, and more common in the higher age group, 80 years and above. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2019-05-29

    Orthostatic hypotension and REM sleep behaviour disorder: impact on clinical outcomes in α-synucleinopathies

    ✓ Peer-reviewed Clinical safety Journal of neurology, neurosurgery, and psychiatry

    Key finding: OH and RBD yielded individual and combined negative effects on disability in α-synucleinopathies, reflecting a 'malignant' phenotype of PD with early cognitive impairment and postural instability. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-05-29

    Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin

    ✓ Peer-reviewed Risk factors Gastroenterology

    Key finding: In a large placebo-controlled randomized trial, we found that pantoprazole is not associated with any adverse event when used for 3 years, with the possible exception of an increased risk of enteric infections. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-05-29

    CNS small vessel disease: A clinical review

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Pathogenesis is thought to begin with an etiologically specific insult, with or without genetic predisposition, which results in dysfunction of the neurovascular unit.

    Full summary, score breakdown and related studies → Original source

  13. 2019-05-29

    The association between subjective caregiver burden and depressive symptoms in carers of older relatives: A systematic review and meta-analysis

    ✓ Peer-reviewed Caregiving PloS one

    Key finding: Subjective caregiver burden is a significant risk factor for depressive symptoms in carers of older people and may precipitate clinical depression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-05-28

    Glia-specific autophagy dysfunction in ALS

    ✓ Peer-reviewed Disease mechanisms Seminars in cell & developmental biology

    Key finding: Therefore, autophagy is considered a critical ND-protective pathway, which opens up potential new therapeutic interventions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-05-28

    Risk Factor Variability and Cardiovascular Outcome: JACC Review Topic of the Week

    ✓ Peer-reviewed Risk factors Journal of the American College of Cardiology

    Key finding: Variability of these risk factors has been demonstrated to be a powerful predictor for all-cause and cardiovascular mortality, stroke, coronary artery disease, heart failure, end-stage renal disease, and dementia.

    Full summary, score breakdown and related studies → Original source

  16. 2019-05-28

    Effects of functional communication interventions for people with primary progressive aphasia and their caregivers: a systematic review

    ✓ Peer-reviewed Digital health tools Aging & mental health

    Key finding: There are variations in the interventions, such as location and dosage. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-05-27

    Apolipoprotein E associated with reconstituted high-density lipoprotein-like particles is protected from aggregation

    ✓ Peer-reviewed Genetics FEBS letters

    Key finding: Apolipoprotein E (APOE) genotype determines Alzheimer's disease (AD) susceptibility, with the APOE ε4 allele being an established risk factor for late-onset AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-05-27

    A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

    ✓ Peer-reviewed Long-term cohort studies Acta neuropathologica

    Key finding: The role of PLCG2 in immune system signaling suggests it may also protect against other neurodegenerative diseases and possibly associates with longevity. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →