alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,626–12,650 of 27,380 studies, newest first · page 506 of 1096.

July 2019 25

  1. 2019-07-29

    Protein-Capped Metal Nanoparticles Inhibit Tau Aggregation in Alzheimer's Disease

    ✓ Peer-reviewed Drug development ACS omega

    Key finding: We present a novel function of PC-Fe 3 O 4 and PC-CdS nanoparticles as potent Tau aggregation inhibitors by fluorescence spectrometry, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and electron microscopy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-07-29

    Patient and Caregiver Benefit From a Comprehensive Dementia Care Program: 1‐Year Results From the UCLA Alzheimer's and Dementia Care Program

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: At year 1, persons with ADRD improved on all scales, except MMSE and functional status measures; caregivers improved on all scales. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-07-29

    The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

    ✓ Peer-reviewed Long-term cohort studies PloS one

    Key finding: The APOE-ε4 allele has long been associated with increased risks of Alzheimer's disease and mortality, but the effect of the less prevalent APOE-ε2 allele on diseases in the elderly and survival remains elusive. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-07-29

    Effects of Digital Device Ownership on Cognitive Decline in a Middle-Aged and Elderly Population: Longitudinal Observational Study

    ✓ Peer-reviewed Digital health tools Journal of medical Internet research

    Key finding: Adjusted for demographic and health behavior as well as health condition risk factors, desktop and cellphone ownership were independently associated with subsequent decreased cognitive decline over the four-year period. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2019-07-27

    Tau and atrophy: domain-specific relationships with cognition

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: FTP and thickness were differentially related to cognitive performance in several domains. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-07-26

    New treatment modalities in Alzheimer's disease

    ✓ Peer-reviewed Drug development World journal of clinical cases

    Key finding: Alzheimer's disease (AD) is still a major public health challenge without an effective treatment to prevent or stop it. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-07-26

    Reciprocal Predictive Relationships between Amyloid and Tau Biomarkers in Alzheimer's Disease Progression: An Empirical Model

    ✓ Peer-reviewed Tau biomarkers The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: In Alzheimer's disease patients, although amyloid deposition and CSF amyloid changes continued to "cascade", there was no evidence to suggest that amyloid and tau biomarkers predicted each other, although both amyloid deposition and CSF tau progression predicted cognitive decline independently.

    Full summary, score breakdown and related studies → Original source

  8. 2019-07-26

    Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Plasma Aβ measures may be useful biomarkers for predicting cerebral Aβ and tau. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2019-07-26

    Diet and Alzheimer's dementia - Nutritional approach to modulate inflammation

    ✓ Peer-reviewed Disease mechanisms Pharmacology, biochemistry, and behavior

    Key finding: This paper summarizes the available evidence of pro- and anti-inflammatory activity of some dietary components including fatty acids, vitamins, flavonoids, polyphenols, probiotics and d-AGE, and their potential for AD prevention and treatment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-07-26

    Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples

    ✓ Peer-reviewed TREM2 and immune genetics Acta neuropathologica

    Key finding: Comprehensive analysis of microglia in different stages of AD in human brains revealed microglia activation to follow the progression of AD neuropathological changes and requiring the co-occurrence of beta-Amyloid (Aβ) and tau pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-07-25

    Linking late life depression and Alzheimer's disease: mechanisms and resilience

    ✓ Peer-reviewed Risk factors Current behavioral neuroscience reports

    Key finding: Three major neurobiological features shared by LLD and AD include neurodegeneration, disruption to cerebrovascular functioning, and increased levels of neuroinflammation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-07-25

    Limited engagement in, yet clear preferences for advance care planning in young-onset dementia: An exploratory interview-study with family caregivers

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: A gap of knowledge, of information and in care intertwiningly hinder advance care planning. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2019-07-24

    Cost containment by peer prior authorization program for second line treatment in patients with retinal disease

    ✓ Peer-reviewed Health systems and care delivery Not indexed

    Key finding: The program made it feasible to finance a costly treatment for patients that may benefit from it, while maintaining qualitative medical outcomes and sparing treating ophthalmologist from ethical gatekeeping dilemmas +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-07-23

    Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study

    ✓ Peer-reviewed Prevention and risk PLoS medicine

    Key finding: With no effective treatments for cognitive decline or dementia, improving the evidence base for modifiable risk factors is a research priority.

    Full summary, score breakdown and related studies → Original source

  15. 2019-07-22

    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Ample evidence suggests that ApoE4 induces microglial dysregulation and impedes Aβ clearance in AD, but the direct neuronal effects of ApoE variants are poorly studied. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-07-22

    Feasibility and Acceptability of Computerised Cognitive Training of Everyday Cognition in Parkinson's Disease

    ✓ Peer-reviewed Cognitive tests and assessment Parkinson's disease

    Key finding: The findings indicated that participants felt the training was acceptable, enhanced their awareness, and encouraged them to monitor their thinking abilities. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-07-22

    Alpha-synuclein structure and Parkinson's disease - lessons and emerging principles

    ✓ Peer-reviewed Getting a diagnosis Molecular neurodegeneration

    Key finding: We do so in the context of a rapidly evolving field, taking into account newly revealed structural information on both native and pathogenic forms of the αS protein, including recent solid state NMR and cryoEM fibril structures.

    Full summary, score breakdown and related studies → Original source

  18. 2019-07-22

    Computerized Cognitive Training in Multiple Sclerosis: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Prevention trials Neurorehabilitation and neural repair

    Key finding: CCT is efficacious for overall and key cognitive domains in adults with MS, but efficacy on other outcomes and in progressive subtypes remains unclear. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2019-07-22

    Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease

    ✓ Peer-reviewed Disease mechanisms Journal of neuroinflammation

    Key finding: Recent results show that perturbation of sphingolipid metabolism can precede or is a part of abnormal protein handling in both genetic and idiopathic Parkinson's disease and Lewy body dementia.

    Full summary, score breakdown and related studies → Original source

  20. 2019-07-22

    Multi-modal latent factor exploration of atrophy, cognitive and tau heterogeneity in Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies NeuroImage

    Key finding: Most previous studies of AD heterogeneity have focused on atypical clinical subtypes, defined subtypes with a single modality, or restricted their analyses to a priori brain regions and cognitive tests. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-07-19

    Diabetes drugs in the fight against Alzheimer's disease

    ✓ Peer-reviewed Drug development Ageing research reviews

    Key finding: Hyperinsulinemia and insulin resistance, which are known as pathophysiological features of Type 2 Diabetes Mellitus (T2DM), have also been demonstrated to have a significant impact on cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2019-07-19

    A Literature Overview of Virtual Reality (VR) in Treatment of Psychiatric Disorders: Recent Advances and Limitations

    ✓ Peer-reviewed Prevention trials Frontiers in psychiatry

    Key finding: Recent advances in VR technology also demonstrate potential abilities to address cognitive and functional impairments in dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-07-19

    Neuroinflammation in frontotemporal dementia

    ✓ Peer-reviewed Inflammation and the immune system Nature reviews. Neurology

    Key finding: Despite advances in understanding the underlying pathology of FTD, sensitive and specific fluid biomarkers for this disease are lacking. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-07-19

    Alzheimer's disease: pathogenesis, diagnostics, and therapeutics

    ✓ Peer-reviewed TREM2 and immune genetics International journal of nanomedicine

    Key finding: Alzheimer's disease (AD) is one of the major causative factors to induce progressive dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-07-18

    Neuroinflammation and Functional Connectivity in Alzheimer's Disease: Interactive Influences on Cognitive Performance

    ✓ Peer-reviewed Mild cognitive impairment The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Multiple linear regression models identified sources of signal covariance between neuroinflammation and brain connectivity profiles, in relation to the diagnostic group (patients, controls) and cognitive status. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →