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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,501–19,525 of 27,380 studies, newest first · page 781 of 1096.

May 2012 3

  1. 2012-05-01

    Predictors of survival in patients with Parkinson disease

    ✓ Peer-reviewed Disparities Archives of neurology

    Key finding: Demographic and clinical factors impact PD survival. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-05-01

    Midlife vs late-life depressive symptoms and risk of dementia: differential effects for Alzheimer disease and vascular dementia

    ✓ Peer-reviewed Getting a diagnosis Archives of general psychiatry

    Key finding: Depressive symptoms in midlife or in late life are associated with an increased risk of developing dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-05-01

    Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: In women, increased plasma adiponectin levels are an independent risk factor for the development of both all-cause dementia and AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

April 2012 22

  1. 2012-04-30

    Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies

    ✓ Peer-reviewed Biomarkers PloS one

    Key finding: Amyloid precursor protein (APP) mutations associated with familial Alzheimer's disease (AD) usually lead to increases in amyloid β-protein (Aβ) levels or aggregation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2012-04-30

    Indicators of Childhood Quality of Education in Relation to Cognitive Function in Older Adulthood

    ✓ Peer-reviewed Risk factors The Journals of Gerontology Series A

    Key finding: Higher student-teacher ratio was associated with worse cognitive function and greater school year length was associated with better cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-04-27

    Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting

    ✓ Peer-reviewed Treatments European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

    Key finding: The brain concentration achieved from i.n. administration of CS-NPs (966 ± 20.66 ng ml(-1); t(max) 60 min) was significantly higher than those achieved after i.v. administration of RHT sol (387 ± 29.51 ngml(-1); t(max) 30 min), and i.n. administration of RHT solution (508.66 ± 22.50 ng ml(-1); t(max) 60 min). +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-04-26

    Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Several recent genome-wide association studies have reported that several single nucleotide polymorphisms (SNPs) in the phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) gene were significantly associated with Alzheimer disease, suggesting a role in APP endocytosis and Aβ generation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2012-04-26

    Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Expression of LRP1 by neurons in proximity to senile amyloid plaques does not appear to play a major role in modulating the formation of these proximal deposits or in the appearance of the associated neuritic pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-04-25

    Disrupted functional brain connectome in individuals at risk for Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Biological psychiatry

    Key finding: This study demonstrates a disruption of whole-brain topological organization of the functional connectome in aMCI. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-04-25

    Is pre-existing dementia an independent predictor of outcome after stroke? A propensity score-matched analysis

    ✓ Peer-reviewed End-of-life care Journal of neurology

    Key finding: Pre-existing dementia is not independently associated with mortality, disability, or institutionalization after ischemic stroke.

    Full summary, score breakdown and related studies → Original source

  8. 2012-04-25

    Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: Moreover, soluble and insoluble pro-aggregant hTau40 disappeared, while insoluble mouse Tau was still present. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-04-25

    An epidemiological study of Alzheimer's disease in elderly Mongolian and Han populations living in rural areas of Inner Mongolia

    ✓ Peer-reviewed Risk factors Aging clinical and experimental research

    Key finding: Analyses revealed that the prevalence rate of AD was 4.79% (SD=4.71%) in the combined Mongolian and Han populations of individuals at least 55 years old and living in rural areas of Inner Mongolia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2012-04-25

    Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Increasing evidence suggests a role of atherosclerosis in the pathogenesis of cognitive impairment and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-04-25

    Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

    ✓ Peer-reviewed Genetics Neurology

    Key finding: MLGPs provide an alternative analytical approach to predict an individual's genetic risk for episodic memory performance, a surrogate indicator of LOAD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-04-24

    Generation of Alzheimer disease-associated amyloid β42/43 peptide by γ-secretase can be inhibited directly by modulation of membrane thickness

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Although the latter cleavages are intramembranous and although lipid alterations have been implicated in AD, little is known of how the γ-secretase-mediated release of the various Aβ species, in particular that of the pathogenic longer variants Aβ(42) and Aβ(43), is affected by the lipid environment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-04-24

    Effects of DHA-rich n-3 fatty acid supplementation on gene expression in blood mononuclear leukocytes: the OmegAD study

    ✓ Peer-reviewed Treatments PloS one

    Key finding: We suggest that 6 months of dietary n-3 FA supplementation affected expression of genes that might influence inflammatory processes and could be of significance for AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2012-04-23

    Effectiveness of cognitive training in Chinese older people with subjective cognitive complaints: a randomized placebo-controlled trial

    ✓ Peer-reviewed Prevention trials International journal of geriatric psychiatry

    Key finding: Cognitive training was effective in enhancing the overall cognitive functioning of less educated older adults with subjective memory complaints. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2012-04-22

    CSF biomarkers cutoffs: the importance of coincident neuropathological diseases

    ✓ Peer-reviewed Biomarkers Acta neuropathologica

    Key finding: The effects of applying clinical versus neuropathological diagnosis and the inclusion of cases with coincident neuropathological diagnoses have not been assessed specifically when studying cerebrospinal fluid (CSF) biomarker classification cutoffs for patients with neurodegenerative diseases that cause dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-04-22

    Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis

    ✓ Peer-reviewed Biomarkers Parkinson's disease

    Key finding: Dementia is a common feature in Parkinson's disease (PD) and is considered to be the result of limbic and cortical Lewy bodies and/or Alzheimer changes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2012-04-21

    Positive effects of computer-based cognitive training in adults with mild cognitive impairment

    ✓ Peer-reviewed Prevention trials Neuropsychologia

    Key finding: Outcome measures showed that the trained group, compared to control group, improved episodic recall and recognition. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2012-04-18

    Prevalence, presentation and prognosis of delirium in older people in the population, at home and in long term care: a review

    ✓ Peer-reviewed Clinical safety International journal of geriatric psychiatry

    Key finding: Delirium in a non-selected population aged 65+ years is uncommon. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2012-04-18

    CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Amyloid plaques and hyperphosphorylated tau in cortical brain biopsies are reflected by low CSF Aβ42 and high CSF tau and p-tau levels, respectively. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2012-04-18

    Total daily physical activity and the risk of AD and cognitive decline in older adults

    ✓ Peer-reviewed Genetics Neurology

    Key finding: A higher level of total daily physical activity is associated with a reduced risk of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2012-04-16

    Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

    ✓ Peer-reviewed Brain tissue and pathology The Journal of experimental medicine

    Key finding: These findings open up new avenues for understanding the progression of PD and for developing novel therapeutics.

    Full summary, score breakdown and related studies → Original source

  22. 2012-04-15

    Common variants at 12q14 and 12q24 are associated with hippocampal volume

    ✓ Peer-reviewed Hippocampus size on brain scans Nature genetics

    Key finding: Aging is associated with reductions in hippocampal volume that are accelerated by Alzheimer's disease and vascular risk factors. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →