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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,401–13,425 of 27,380 studies, newest first · page 537 of 1096.

December 2018 25

  1. 2018-12-14

    Antemortem CSF Aβ42/Aβ40 ratio predicts Alzheimer's disease pathology better than Aβ42 in rapidly progressive dementias

    ✓ Peer-reviewed Biomarkers Annals of clinical and translational neurology

    Key finding: The score reflecting the severity of Aβ pathology showed a better correlation with ln(Aβ42/Aβ40) (R 2 = 0.506, β = -0.713, P < 0.001) than with ln(Aβ42) (R 2 = 0.206, β = -0.458, P < 0.001), which was confirmed after adjusting for covariates. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2018-12-14

    Timing of Palliative Care Consultation and the Impact on Thirty-Day Readmissions and Inpatient Mortality

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: Inpatient PCC reduces 30-day readmissions and inpatient mortality with the greatest impact demonstrated within six days of hospital admission. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2018-12-13

    Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART; alz.org/ISTAART) comprises a number of professional interest areas (PIAs), each focusing on a major scientific area associated with ADRDs.

    Full summary, score breakdown and related studies → Original source

  4. 2018-12-13

    Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Drug development Acta neuropathologica

    Key finding: N-224 tau was lower in the AD soluble brain fraction compared to controls, while N-123 tau showed similar levels. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2018-12-13

    Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases

    ✓ Peer-reviewed Vascular contributions Molecules (Basel, Switzerland)

    Key finding: NAC is a glutathione precursor and shows antioxidant and anti-inflammatory activities. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2018-12-13

    Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

    ✓ Peer-reviewed Disease mechanisms Translational psychiatry

    Key finding: We found that the expression of the MAPT p.R406W mutation was sufficient to create a significantly different transcriptomic profile compared with that of the isogeneic controls and to cause the differential expression of 328 genes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2018-12-13

    Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia

    ✓ Peer-reviewed How common it is Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: SCD can precede both AD and non-AD dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2018-12-13

    The Multidisciplinary Approach to Alzheimer's Disease and Dementia. A Narrative Review of Non-Pharmacological Treatment

    ✓ Peer-reviewed Caregiving Frontiers in neurology

    Key finding: The role of NPT has been largely explored in AD and dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2018-12-12

    Exercise Improves Vascular Function, but does this Translate to the Brain?

    ✓ Peer-reviewed Prevention trials Brain plasticity (Amsterdam, Netherlands)

    Key finding: Aging and cardiovascular disease risk factors are associated with reduced vascular function, which can have important clinical implications, including brain health. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2018-12-12

    Exercise and the Aging Brain: Considerations for Sex Differences

    ✓ Peer-reviewed Prevention trials Brain plasticity (Amsterdam, Netherlands)

    Key finding: Sex differences exist in dementia as well as in several associated risk factors, including genetics, cardiovascular factors, inflammation, hormones and social and psychological factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2018-12-12

    Attributable risk of hospital admissions for overall and specific mental disorders due to particulate matter pollution: A time-series study in Chengdu, China

    ✓ Peer-reviewed Risk factors Environmental research

    Key finding: The associations of particulate matter (PM) pollution with the morbidity of overall and subtypes of mental disorders (MDs), as well as the corresponding morbidity burden, remain understudied, especially in developing countries. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2018-12-12

    Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study

    ✓ Peer-reviewed Hippocampus size on brain scans PloS one

    Key finding: Older age was associated with baseline Aβ and neurodegeneration markers, but not with rates of change in these biomarkers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2018-12-12

    Herbal Medicine Ninjin'yoeito in the Treatment of Sarcopenia and Frailty

    ✓ Peer-reviewed End-of-life care Frontiers in nutrition

    Key finding: It is important to prevent progression of frailty and extend the healthy lifespan. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2018-12-12

    CD33 in Alzheimer's Disease - Biology, Pathogenesis, and Therapeutics: A Mini-Review

    ✓ Peer-reviewed TREM2 and immune genetics Gerontology

    Key finding: With continuous failure of anti-amyloid-beta- or tau-based therapies, identification of new targets has become an urgent necessity for AD prevention and therapy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2018-12-12

    Circulating levels of IL-1 family cytokines and receptors in Alzheimer's disease: new markers of disease progression?

    ✓ Peer-reviewed Mild cognitive impairment Journal of neuroinflammation

    Key finding: AD is characterised by a significant alteration in the circulating levels of the cytokines and receptors of the IL-1 family. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2018-12-11

    Optical coherence tomography in the investigation of systemic neurologic disease

    ✓ Peer-reviewed Brain scans and imaging Clinical & experimental optometry

    Key finding: The application of this technology has more recently been extended beyond ophthalmic disease, whereby it has been demonstrated that OCT can serve as an ophthalmic marker for a range of systemic neurodegenerative disorders, such as Parkinson's disease, multiple sclerosis, Alzheimer's disease and diabetic peripheral neuropathy.

    Full summary, score breakdown and related studies → Original source

  17. 2018-12-11

    Impact of Metabolic Syndrome on Neuroinflammation and the Blood-Brain Barrier

    ✓ Peer-reviewed Disease mechanisms Frontiers in neuroscience

    Key finding: Neuropathologies triggered by metabolic syndrome often result from increased permeability of the blood-brain-barrier (BBB).

    Full summary, score breakdown and related studies → Original source

  18. 2018-12-11

    Development and Validation of a Dementia Risk Prediction Model in the General Population: An Analysis of Three Longitudinal Studies

    ✓ Peer-reviewed Long-term cohort studies The American journal of psychiatry

    Key finding: Identification of individuals at high risk of dementia is essential for development of prevention strategies, but reliable tools are lacking for risk stratification in the population. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2018-12-11

    TREM2 triggers microglial density and age-related neuronal loss

    ✓ Peer-reviewed TREM2 and immune genetics Glia

    Key finding: Genetic variants or mutations of TREM2 or TYROBP have been linked to inflammatory neurodegenerative diseases associated with aging. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2018-12-11

    Neuroimaging and Machine Learning for Dementia Diagnosis: Recent Advancements and Future Prospects

    ✓ Peer-reviewed Digital health tools IEEE reviews in biomedical engineering

    Key finding: Based on the rigorous review of the existing works, we have found that, while most of the studies focused on Alzheimer's disease, recent research has demonstrated reasonable performance in the identification of other types of dementia remains a major challenge. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2018-12-10

    Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial

    ✓ Peer-reviewed Clinical trials Clinical nutrition (Edinburgh, Scotland)

    Key finding: Overall, we found that probiotic and selenium co-supplementation for 12 weeks to patients with AD improved cognitive function and some metabolic profiles. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2018-12-10

    Factors influencing attrition in 35 Alzheimer's Disease Centers across the USA: a longitudinal examination of the National Alzheimer's Coordinating Center's Uniform Data Set

    ✓ Peer-reviewed Long-term cohort studies Aging clinical and experimental research

    Key finding: A lack of understanding of the causes of attrition in longitudinal studies of older adults may lead to higher attrition rates and bias longitudinal study results. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2018-12-09

    Oxidative Stress and the Microbiota-Gut-Brain Axis

    ✓ Peer-reviewed Disease mechanisms Oxidative medicine and cellular longevity

    Key finding: The gut-brain axis is increasingly recognized as an important pathway of communication and of physiological regulation, and gut microbiota seems to play a significant role in this mutual relationship. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2018-12-07

    The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: We summarise the literature fluctuating from the protective and detrimental properties that cytokines, leukocytes and glial cells play in the acute and chronic stages of TBI, including the intrinsic factors that influence cytokine responses and microglial functions relative to genetics, sex, and age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2018-12-07

    Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke

    ✓ Peer-reviewed TREM2 and immune genetics Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

    Key finding: We previously showed that TREM2 deficiency worsened outcomes from experimental stroke and impeded phagocytosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →