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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,651–25,675 of 27,380 studies, newest first · page 1027 of 1096.

November 1999 5

  1. 1999-11-01

    The Clock Drawing Test: utility for dementia detection in multiethnic elders

    ✓ Peer-reviewed Disparities The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Overall, the CDT may be as effective as the MMSE or CASI as a first-level dementia screen for clinical use in multiethnic, multilingual samples of older adults. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-11-01

    Comorbidity in arthritis

    ✓ Peer-reviewed Caregiving The Journal of rheumatology

    Key finding: These data indicate that the burden of illness among people with arthritis is higher than for nonarthritics and that this burden appears to be increasing over time, particularly in RA. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-11-01

    Validation of a 6 item cognitive impairment test with a view to primary care usage

    ✓ Peer-reviewed Getting a diagnosis International journal of geriatric psychiatry

    Key finding: Two hundred and eighty-seven patients were tested: 135 controls (GDS 1-2), 70 with mild dementia (GDS 3-5) and 82 with more severe dementia (GDS 6-7).

    Full summary, score breakdown and related studies → Original source

  4. 1999-11-01

    Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion

    ✓ Peer-reviewed Treatments Methods and findings in experimental and clinical pharmacology

    Key finding: Citicoline has been extensively used for the treatment of neurodegenerative disorders associated with head trauma, stroke, brain aging, cerebrovascular pathology and Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 1999-11-01

    Encephalopathy with idiopathic hyperammonaemia and Alzheimer type II astrocytes in equidae

    ✓ Peer-reviewed Biomarkers Equine veterinary journal

    Key finding: Histologically, all 3 cases revealed diffuse Alzheimer type II astrocytes in the cerebral grey matter.

    Full summary, score breakdown and related studies → Original source

October 1999 16

  1. 1999-10-22

    β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

    ✓ Peer-reviewed Disease mechanisms Science

    Key finding: A transmembrane aspartic protease with all the known characteristics of beta-secretase was cloned and characterized. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-10 month only

    Rivastigmine, a brain-region selective acetylcholinesterase inhibitor for treating Alzheimer's disease: review and current status

    ✓ Peer-reviewed Treatments Expert opinion on investigational drugs

    Key finding: Early studies demonstrated that rivastigmine improved cognition and was relatively well-tolerated at moderate doses. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-10-01

    Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?

    ✓ Peer-reviewed Drug development Biological psychiatry

    Key finding: Chronic lithium treatment has been demonstrated to markedly increase the levels of the major neuroprotective protein, bcl-2 in rat frontal cortex, hippocampus, and striatum. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1999-10-01

    Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration

    ✓ Peer-reviewed Drug development The Journal of biological chemistry

    Key finding: These findings indicate that MAP kinase mediates multiple aspects of betaA-induced neurotoxicity and indicates that calcium influx initiates neurodegeneration in AD. betaA increased MAP kinase-mediated phosphorylation of membrane-associated proteins and reduced phosphorylation of cytosolic proteins without increasing overall MAP kinase activity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 1999-10-01

    Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: These findings require further work to determine if the abnormalities are an expression of the genetic liability to schizophrenia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 1999-10-01

    Clinical and quantitative pathologic correlates of dementia with Lewy bodies

    ✓ Peer-reviewed Clinical safety Neurology

    Key finding: There is a consistent pattern of vulnerability to LB formation across subcortical, paralimbic, and neocortical structures that is similar for DLB cases with or without concomitant AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 1999-10-01

    Psychiatric medication and abnormal behavior as predictors of progression in probable Alzheimer disease

    ✓ Peer-reviewed Clinical safety Archives of neurology

    Key finding: These findings indicate that the use of antipsychotic agents and sedatives can affect the natural course of Alzheimer disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 1999-10-01

    The risk of dementia and death after delirium

    ✓ Peer-reviewed Clinical safety Age and ageing

    Key finding: Design prospective cohort study. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 1999-10-01

    Alpha-synuclein in Lewy body disease and Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Brain pathology (Zurich, Switzerland)

    Key finding: Previous studies have shown that cognitive alterations in these disorders are associated with synaptic loss. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 1999-10-01

    Gonadal function in young women with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    Key finding: The patients were at stage V of sexual development. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 1999-10-01

    Overlap between pathology of Alzheimer disease and vascular dementia

    ✓ Peer-reviewed Risk factors Alzheimer disease and associated disorders

    Key finding: There is overwhelming evidence to suggest that the neuropathology of Alzheimer disease (AD) extends beyond amyloid plaques and neurofibrillary tangles. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 1999-10-01

    Cellular co-localization of phosphorylated tau- and NACP/alpha-synuclein-epitopes in lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies

    ✓ Peer-reviewed Disparities Brain research

    Key finding: Double-immunofluorescence study and peroxidase-immunohistochemical study in serial sections, performed to examine the co-localization of tau- and NACP-epitopes in the brainstem of PD and DLB, demonstrated that four different epitopes of tau including phosphorylation-dependent and independent ones were present in a minority of LBs, but more often than previously considered. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 1999-10-01

    Self-reported exercise tolerance and the risk of serious perioperative complications

    ✓ Peer-reviewed Prevention and risk Archives of internal medicine

    Key finding: Impaired exercise tolerance during formal testing is predictive of perioperative complications.

    Full summary, score breakdown and related studies → Original source

  14. 1999-10-01

    Clinical trials of propentofylline in vascular dementia. European/Canadian Propentofylline Study Group

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: In addition, the inclusion of patients with possible VaD in this trial greatly increased the number of eligible patients; subgroup analyses revealed no substantial differences between patients with probable versus possible VaD, justifying their inclusion in the study. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 1999-10-01

    Evidence for an interaction between apolipoprotein E genotype, gender, and Alzheimer disease

    ✓ Peer-reviewed Genetics Alzheimer disease and associated disorders

    Key finding: Carriers of the apolipoprotein E (APOE) epsilon4 allele show significantly higher risk of Alzheimer disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 1999-10-01

    Cerebrospinal fluid markers of pathogenetic processes in vascular dementia, with special reference to the subcortical subtype

    ✓ Peer-reviewed Biomarkers Alzheimer disease and associated disorders

    Key finding: The clinical diagnosis of subcortical VaD may be difficult because the clinical manifestation of this disorder is often similar to that of Alzheimer disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

September 1999 4

  1. 1999-09-15

    Longitudinal stability of CSF tau levels in Alzheimer patients

    ✓ Peer-reviewed Tau biomarkers Biological psychiatry

    Key finding: Despite significant changes in the clinical measures consistent with progression of the disease, no significant overall change in CSF tau levels (548 +/- 355 vs. 557 +/- 275 pg/mL, NS) was observed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 1999-09-01

    Health benefits of docosahexaenoic acid (DHA)

    ✓ Peer-reviewed Risk factors Pharmacological research

    Key finding: The inclusion of plentiful DHA in the diet improves learning ability, whereas deficiencies of DHA are associated with deficits in learning. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 1999-09-01

    Astrocytes expressing hyperphosphorylated tau protein without glial fibrillary tangles in argyrophilic grain disease

    ✓ Peer-reviewed Drug development Acta neuropathologica

    Key finding: We now extend earlier studies on glial pathology in AgD (20 cases) and compare the results with glial changes in old age (10 cases) and Alzheimer's disease (AD; 7 cases). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 1999-09-01

    The physiological approach: functional architecture of working memory and disordered cognition in schizophrenia

    ✓ Peer-reviewed Genetics Biological psychiatry

    Key finding: Limitations of this approach include the inability to unequivocally identify the cell under investigation, though location by cytoarchitectonic area and cortical depth is possible. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →