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Life Expectancy With and Without Dementia: A Population-Based Study of Dementia Burden and Preventive Potential
Wolters FJ, Tinga LM, Dhana K, Koudstaal PJ, Hofman A, Bos D, Franco OH, Ikram MA.. American journal of epidemiology, 2019-02-01
Topic: Risk, prevention and care in population studies
Reliable population estimates of life expectancy with dementia are required for shaping health-care policy. From the Dutch, population-based Rotterdam Study, 10,348 persons were followed during 1990-2015 for dementia and death. We created multistate lifetables, and assessed the effect of postponing disease onset.
Key findings
- From the Dutch, population-based Rotterdam Study, 10,348 persons were followed during 1990-2015 for dementia and death.
- We created multistate lifetables, and assessed the effect of postponing disease onset.
- During 120,673 person-years, 1,666 persons developed dementia, and 6,150 died.
- Overall life expectancy of women ranged from 18.0 years (95% confidence interval (CI): 17.8, 18.2) at age 65 to 2.3 years (95% CI: 2.2, 2.3) at age 95.
Why it matters
This population-based study estimated life expectancy with and without dementia and assessed the effect of postponing disease onset. It is about planning health care and does not show that any specific treatment or prevention works.
Study details
- Participants10,348
- Effect size5.7%; 42.1%; 3.7%
- Evidence strengthLow
How this study scored 53/100
Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (American journal of epidemiology) |
| Journal's citation record | 3 / 4 | American Journal of Epidemiology: journal h-index 416 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2019 — within 10 year(s) of the newest study here |
| Sample size | 4 / 4 | 10,348 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 4 / 7 | Cited 50 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 5.6 citations a year over 9 year(s) since 2019 |
| Impact for its field and year | 2 / 6 | Cited 2.8× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 2 other studies in this library |
| Still being cited | 2 / 4 | Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author M. Arfan Ikram: h-index 167 (OpenAlex, whole career) |
| Institution's track record | 3 / 3 | Harvard University: institution h-index 3,235 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 3 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 30299452) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 53 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1093/aje/kwy234
- PubMed: 30299452
- Original source →
- Free full text: American Journal of Epidemiology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 8 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Wolters, F. J., Tinga, L. M., Dhana, K., Koudstaal, P. J., Hofman, A., Bos, D., et al. (2019). Life Expectancy With and Without Dementia: A Population-Based Study of Dementia Burden and Preventive Potential. American journal of epidemiology. https://doi.org/10.1093/aje/kwy234
Vancouver
Wolters FJ, Tinga LM, Dhana K, Koudstaal PJ, Hofman A, Bos D, et al. Life Expectancy With and Without Dementia: A Population-Based Study of Dementia Burden and Preventive Potential. American journal of epidemiology. 2019. doi:10.1093/aje/kwy234. PMID: 30299452.
BibTeX
@article{wolters2019-30299452,
author = {Wolters, F. J. and Tinga, L. M. and Dhana, K. and Koudstaal, P. J. and Hofman, A. and Bos, D. and Franco, O. H. and Ikram, M. A.},
title = {{Life Expectancy With and Without Dementia: A Population-Based Study of Dementia Burden and Preventive Potential}},
journal = {American journal of epidemiology},
year = {2019},
doi = {10.1093/aje/kwy234},
pmid = {30299452},
url = {https://doi.org/10.1093/aje/kwy234}
}
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