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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,976–13,000 of 27,380 studies, newest first · page 520 of 1096.

March 2019 25

  1. 2019-03-29

    Current and Future Treatments in Alzheimer's Disease

    ✓ Peer-reviewed Treatments Seminars in neurology

    Key finding: When combined, pharmacologic and nonpharmacologic treatments can meaningfully mitigate symptoms and reduce clinical progression and care burden. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-03-29

    Association of Sensory and Cognitive Impairment With Healthcare Utilization and Cost in Older Adults

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Older adults with sensory and cognitive impairments constitute a particularly prevalent and vulnerable population who are at increased risk of hospitalization and contribute to higher healthcare spending. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-03-29

    Alzheimer's Disease Including Focal Presentations

    ✓ Peer-reviewed Disease mechanisms Seminars in neurology

    Key finding: The main clinical phenotype at presentation is the amnestic phenotype targeting episodic memory. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-03-29

    Radiomics: a novel feature extraction method for brain neuron degeneration disease using 18F-FDG PET imaging and its implementation for Alzheimer's disease and mild cognitive impairment

    ✓ Peer-reviewed Long-term cohort studies Therapeutic advances in neurological disorders

    Key finding: Alzheimer's disease (AD) is the most common form of progressive and irreversible dementia, and accurate diagnosis of AD at its prodromal stage is clinically important. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-03-29

    Progressive Tau Accumulation in Alzheimer Disease: 2-Year Follow-up Study

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: In contrast to no change in global cortical SUVR in the CU- and CU+ groups during the 2-y period, global cortical SUVR increased by 0.06 (2.9%) in the MCI+ group and 0.19 (8.0%) in the DEM+ group at follow-up. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-03-28

    A pilot study of fluorescence lifetime imaging ophthalmoscopy in preclinical Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Eye (London, England)

    Key finding: This prospective, observational study enrolled patients with early AD undergoing Alzheimer's biomarker analysis and matched controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-03-28

    A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth

    ✓ Peer-reviewed TREM2 and immune genetics Cell stem cell

    Key finding: Here, we show that Oncostatin M (OSM), an IL-6 family cytokine, negatively regulates hair growth by signaling through JAK-STAT5 to maintain HFSC quiescence. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-03-28

    Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia

    ✓ Peer-reviewed Digital health tools Annals of neurology

    Key finding: Postmortem cortical pathology was left-lateralized in both FTLD-TDP (beta = -0.15, standard error [SE] = 0.05, p = 0.007) and FTLD-Tau (beta = -0.09, SE = 0.04, p = 0.015), but the degree of lateralization decreased with greater overall dementia severity before death (beta = -8.18, SE = 3.22, p = 0.015). +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2019-03-27

    Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies

    ✓ Peer-reviewed Brain scans and imaging EJNMMI research

    Key finding: [18F]Flutemetamol and [18F]florbetaben data demonstrated an increased bias in amyloid estimate for larger intervals and higher noise levels. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-03-27

    Mobile-Health Applications for the Efficient Delivery of Health Care Facility to People with Dementia (PwD) and Support to Their Carers: A Survey

    ✓ Peer-reviewed Prevention trials BioMed research international

    Key finding: The comprehensive study concluded that mobile health apps appear as feasible AT intervention for PwD and their carers irrespective of limited available research, but these apps have potential to provide different resources and strategies to help this community.

    Full summary, score breakdown and related studies → Original source

  11. 2019-03-27

    PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca2+ homeostasis

    ✓ Peer-reviewed Risk genes beyond APOE Autophagy

    Key finding: In addition to its well-known role within the γ-secretase complex (the enzyme ultimately responsible for Aβ peptides formation), PSEN2 is endowed with some γ-secretase-independent functions in distinct cell signaling pathways, such as the modulation of intracellular Ca 2+ homeostasis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-03-27

    Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: Our results demonstrate that endogenous expression of E4 by stem-cell-derived forebrain excitatory neurons predisposes neurons to calcium dysregulation and ultimately cell death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-03-26

    The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models

    ✓ Peer-reviewed Tau biomarkers Frontiers in neuroscience

    Key finding: Recent research evidence is now emerging in support of its therapeutic potential for different pathologies including neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-03-26

    Analysis of 50 Neurodegenerative Genes in Clinically Diagnosed Early-Onset Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics International journal of molecular sciences

    Key finding: Previous studies revealed that many causative mutations in AD, PD, and FTD/ALS genes could be found in clinical familial and sporadic AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-03-26

    Characterization of White Matter Hyperintensities in Large-Scale MRI-Studies

    ✓ Peer-reviewed Disparities Frontiers in neurology

    Key finding: Our search resulted in the inclusion and full-text review of 137 articles. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-03-26

    Long-Term Outcomes of the Benefit-Finding Group Intervention for Alzheimer Family Caregivers: A Cluster-Randomized Double-Blind Controlled Trial

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Benefit-finding reduces depressive symptoms as well as global burden in the long-term and increases psychological well-being in the medium-term.

    Full summary, score breakdown and related studies → Original source

  17. 2019-03-25

    Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

    ✓ Peer-reviewed Brain scans and imaging eLife

    Key finding: We employed targeted protein degradation technology to convert a tau PET-probe into a functional degrader of pathogenic tau. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-03-25

    Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model

    ✓ Peer-reviewed TREM2 and immune genetics Nature communications

    Key finding: A proteolytic product, soluble TREM2 (sTREM2), is abundant in the cerebrospinal fluid and its levels positively correlate with neuronal injury markers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2019-03-25

    SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data

    ✓ Peer-reviewed Risk genes beyond APOE Acta neuropathologica

    Key finding: SORL1 encodes SorLA, a key protein involved in the processing of the amyloid-beta (Aβ) precursor protein (APP) and the secretion of the Aβ peptide, the aggregation of which triggers AD pathophysiology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2019-03-25

    Cognitive training for people with mild to moderate dementia

    ✓ Peer-reviewed Caregiving The Cochrane database of systematic reviews

    Key finding: Relative to a control condition, we found moderate-quality evidence showing a small to moderate effect of CT on our first primary outcome, composite measure of global cognition at end of treatment (standardised mean difference (SMD) 0.42, 95% confidence interval (CI) 0.23 to 0.62), and high-quality evidence showing a moderate effect on the secondary outcome of verbal semantic fluency (SMD 0.52, 95% CI 0.23 to 0.81) at end of treatment, with these gains retained in the medium term (3 to 12 months post treatment). +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-03-24

    Neurofilament light chain as a blood biomarker to differentiate psychiatric disorders from behavioural variant frontotemporal dementia

    ✓ Peer-reviewed Biomarkers Journal of psychiatric research

    Key finding: The schizophrenia, depression and bipolar patients did not show significant changes in serum NfL levels in comparison to the control group (p > 0.99). +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2019-03-23

    Safety and efficacy of active and passive immunotherapy in mild-to-moderate Alzheimer's disease: A systematic review and network meta-analysis

    ✓ Peer-reviewed Treatments Clinical and investigative medicine. Medecine clinique et experimentale

    Key finding: In terms of efficacy, the review showed a statistically, but not clinically significant, improvement in favor of immunotherapy versus placebo. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-03-23

    Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment BMJ open

    Key finding: Recent failures of potential novel therapeutics for Alzheimer's disease (AD) have prompted a drive towards clinical studies in prodromal or preclinical states. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2019-03-23

    Causes and outcomes of hospitalization in Lewy body dementia: A retrospective cohort study

    ✓ Peer-reviewed End-of-life care Parkinsonism & related disorders

    Key finding: The most common reasons for hospitalization in LBD are potentially modifiable. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2019-03-22

    The role of ABCA7 in Alzheimer's disease: evidence from genomics, transcriptomics and methylomics

    ✓ Peer-reviewed Genetics Acta neuropathologica

    Key finding: Methylation at several CpG sites in the ABCA7 locus is significantly associated with AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →