Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 501–525 of 27,380 studies, newest first · page 21 of 1096.
September 2026 25
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2026-09-10
Digital motor and cognitive variability as early markers of the prodromal Parkinson’s disease spectrum
16/100 ⚠ Preprint — not yet peer-reviewed Mild cognitive impairment medRxiv
Key finding: Performance variability precedes measurable linear decline across PD-risk stratified groups. +3 more findings
Scored 39 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
nterpretable Alzheimer’s Disease Detection from CHAT Transcripts Using Criterion-Guided LLM Prompting and In-Context Learning
16/100 ⚠ Preprint — not yet peer-reviewed Digital health tools Research Square
Key finding: Early detection of Alzheimer’s disease (AD) from spontaneous speech remains a clinically significant challenge.
Scored 24 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Brain Iron Accumulation and Its Cognitive and Olfactory Correlates in Late-Life Depression
16/100 ⚠ Preprint — not yet peer-reviewed Risk factors Research Square
Key finding: Late-life depression (LLD) is associated with cognitive impairment, olfactory dysfunction and dementia risk, while brain iron accumulation has been linked to depressive symptoms, cognitive impairment and Alzheimer’s disease progression. +2 more findings
Scored 27 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Coronary artery disease and neurocognitive performance among older adults in Uganda
16/100 ⚠ Preprint — not yet peer-reviewed Risk factors Research Square
Key finding: CAD was not associated with global or domain-level neurocognitive performance. +4 more findings
Scored 47 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Hypertension is associated with better brain health outcomes in older-age asymptomatic carotid disease populations - A Multi-Cohort Study
16/100 ⚠ Preprint — not yet peer-reviewed Risk factors Research Square
Key finding: Hypertension is associated with lower risk of dementia-related outcomes in aECAD patients. +4 more findings
Scored 26 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Development and feasibility of a theory-driven multidomain intervention for community-dwelling older adults with mild cognitive impairment: a quasi-experimental pilot study based on the Multi-Theory Model
16/100 ⚠ Preprint — not yet peer-reviewed Prevention trials Research Square
Key finding: Forty participants completed the study (intervention, n = 21; control, n = 19). +3 more findings
Scored 37 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
MRI-derived periventricular diffusivity contextualizes plasma pTau217 associations with Alzheimer pathology: a discovery–validation study
16/100 ⚠ Preprint — not yet peer-reviewed Brain scans and imaging Research Square
Key finding: PVeD reproducibly contextualized associations between plasma pTau217 and PET-defined Alzheimer pathology across cohorts with different participant composition, pTau217 assays, PET tracers, and cognitive measures. +1 more finding
Scored 29 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Efficacy of care management in reducing needs of caregivers of people with dementia
16/100 ⚠ Preprint — not yet peer-reviewed Cognitive tests and assessment Research Square
Key finding: Our study delivers ambivalent results for the efficacy of care management for caregivers. +2 more findings
Scored 53 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Amplitude of physiological brain pulsations in Alzheimer’s disease
16/100 ⚠ Preprint — not yet peer-reviewed Tau biomarkers Research Square
Key finding: The very low frequency (< 0.1 Hz) vasomotor waves, respiratory and cardiac frequencies and cardiorespiratory modulation all displayed significantly higher amplitudes in overlapping brain structures of AD patients compared to the controls. +1 more finding
Scored 21 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Comparison of Expert Reads Versus Local Clinical Reads of Amyloid PET Scans in the IDEAS Study
37/100 ✓ Peer-reviewed Health systems and care delivery Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Key finding: Participants were a median age of 75 y (range, 65-96 y), 51.4% were female, and 60.5% had mild cognitive impairment. +4 more findings
Full summary, score breakdown and related studies → Original source
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2026-09-10
Endocannabinoid System Genes in Dementia: A Systematic Mendelian Randomization Study of Functional Variants and Tissue-Specific Expression Across Clinical, Molecular, and Neuroimaging Phenotypes
16/100 ⚠ Preprint — not yet peer-reviewed Lewy body dementia medRxiv (preprint)
Key finding: ResultsThe CNR2 missense variant rs4649124 was associated with increased vascular dementia risk (BH-adjusted P = 0.049) after correction at the 5% false discovery rate (FDR) threshold, with additional associations at the 10% FDR threshold for all-cause dementia risk (BH-adjusted P = 0.051) and lower +4 more findings
Scored 23 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Structural, Functional and Cognitive Validation of a Deep-Learning MCI-to-AD Conversion Model in OASIS-3
16/100 ⚠ Preprint — not yet peer-reviewed Brain scans and imaging medRxiv (preprint)
Key finding: Risk also tracked the multi-year rate of cognitive decline and, at baseline, was associated with reduced within-network functional-connectivity integrity, concentrated in salience and default-mode hubs; longitudinal functional analyses were underpowered.
Scored 34 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Errorless learning of a video call in Alzheimer Disease: verbal motor error dissociation as a potential marker of procedural learning (a pilot study)
16/100 ⚠ Preprint — not yet peer-reviewed Risk genes beyond APOE medRxiv (preprint)
Key finding: Verbal and motor errors followed significantly different courses across steps: verbal errors were present from the first trial and fell close to zero by the last step of the second session, whereas motor errors increased.
Scored 19 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-10
Effects of sex, treatment resistance, and antidepressant treatment on monoamine oxidase B total distribution volume
16/100 ⚠ Preprint — not yet peer-reviewed How common it is medRxiv (preprint)
Key finding: A subset of NTR-MDE and TRD (n=13) were scanned before and after treatment with phenelzine, rasagiline, or duloxetine. [11C]SL25.1188 VT was higher in grey matter regions in females (10%, p<.001). [11C]SL25.1188 VT was also higher in prefrontal cortex in TRD compared to HC (23%, p<.001) and TRD comp +1 more finding
Scored 29 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
How Reliable and Explainable Are Machine Learning Models for Dementia Detection? A Leakage-Aware Evaluation
16/100 ⚠ Preprint — not yet peer-reviewed Cognitive tests and assessment Research Square
Key finding: MMSE alone gives mean fold ROC-AUC of 0.85 to 0.86. +4 more findings
Scored 32 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
Characterization of MTHFR Coding Variants in Indonesian Patients With Vascular Dementia: An Exploratory Sequencing Study
59/100 ✓ Peer-reviewed Vascular contributions F1000Res
Key finding: Multiple MTHFR coding variants were identified in this small Indonesian VaD cohort. +1 more finding
Full summary, score breakdown and related studies → Original source
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2026-09-09
Comparative comorbidity burden in hospitalized primary Parkinson's disease and secondary parkinsonism: a cross-sectional study from Southwest China
16/100 ⚠ Preprint — not yet peer-reviewed Risk factors Research Square
Key finding: The study evaluated 1,457 PD patients (1,050 primary; 407 secondary) alongside 2,100 matched non-PD controls. +4 more findings
Scored 27 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
Association Between Combined Multiple Behaviors and Cognitive Impairment in Older Adults: A 10-Year Cohort Study
16/100 ⚠ Preprint — not yet peer-reviewed Risk factors Preprints.org
Key finding: Of total 8,321 participants, 24.88% (2,070) developed cognitive impairment during a 10-year follow-up. +4 more findings
Scored 48 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
A Physicist's Perspective on Metabolic Rejuvenation After 50
16/100 ⚠ Preprint — not yet peer-reviewed Brain scans and imaging Preprints.org
Key finding: Our liver acts as an emergency overflow reservoir, converting excess glucose into triglycerides, leading to visceral adiposity, which systematically suffocates our pancreas and gallbladder. +4 more findings
Scored 21 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
Universal Dimensional Scaling in Information-Geometric Rendering: Substrate-Independent Metric Conservation Across Holographic, Biological, and Engineered Manifolds
16/100 ⚠ Preprint — not yet peer-reviewed Brain scans and imaging PsyArXiv
Key finding: In the primary visual cortex (V1), we show that cortical magnification (M) is a deterministic Riemannian coordinate transformation (M \propto 1/\sqrt{\det g}) that equalizes information pressure between the spherical retina and planar cortex.2. +4 more findings
Scored 21 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
[Antibody therapy in Alzheimer's disease]
45/100 ✓ Peer-reviewed Treatments Zeitschrift fur Gerontologie und Geriatrie
Key finding: Both reduce Aβ plaques and slow cognitive decline. +4 more findings
Full summary, score breakdown and related studies → Original source
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2026-09-09
Smartphone barrier: uncovering the digital divide in mHealth prevention among disadvantaged middle-aged and older-aged UK communities
51/100 ✓ Peer-reviewed Risk factors BMJ digital health & AI
Key finding: Individuals in mid-to-late life at increased risk of developing dementia based on their risk profile. +1 more finding
Full summary, score breakdown and related studies → Original source
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2026-09-09
Expert opinion on Alzheimer's disease diagnostics and management in Central Eastern European countries representing 88 million population
44/100 ✓ Peer-reviewed Health systems and care delivery Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Key finding: The panel suggested that CEE countries should involve various stakeholders, policymakers, implement routine screening, combine advanced diagnostic tools and use telemedicine and remote monitoring technologies, invest in research to develop AI-based analyses, new AD diagnostic and monitoring methods, digital tools and wearables.
Full summary, score breakdown and related studies → Original source
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2026-09-09
Sex-aware Cross-tissue Regulatory Transformer Identified Sexually Dimorphic Alzheimer's Disease Risk Loci and Causal Cellular Circuit
16/100 ⚠ Preprint — not yet peer-reviewed Genetics medRxiv (preprint)
Key finding: Sex-stratified analyses identified eight female and three male genome-wide-significant signals provisionally classified as novel. +2 more findings
Scored 31 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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2026-09-09
Rare extreme polygenic risk scores strongly indicate Alzheimer's disease risk
16/100 ⚠ Preprint — not yet peer-reviewed Genetics medRxiv (preprint)
Key finding: ResultsIndividuals in the extreme upper PRS tail were significantly enriched for AD in all ancestries: Admixed American (Padj=0.02727), African (Padj=0.004827), East Asian (Padj=0.02824), and European (Padj=2.3068x10-13).
Scored 18 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.
Full summary, score breakdown and related studies → Original source
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