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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,251–19,275 of 27,380 studies, newest first · page 771 of 1096.

September 2012 7

  1. 2012-09-01

    Treatment strategies targeting amyloid β-protein

    ✓ Peer-reviewed Risk genes beyond APOE Cold Spring Harbor perspectives in medicine

    Key finding: This effort fully matured when it was clarified that the Aβ is a normal product of cleavage of the amyloid precursor protein, and well-defined proteases for this process were identified. +2 more findings

  2. 2012-09-01

    Plasma microRNA biomarkers for detection of mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Aging

    Key finding: Early stages of many neurodegenerative diseases, such as Alzheimer's disease, vascular and frontotemporal dementia, and Parkinson's disease, are frequently associated with Mild Cognitive Impairment (MCI). +1 more finding

  3. 2012-09-01

    Derivation and validation of automated electronic search strategies to extract Charlson comorbidities from electronic medical records

    ✓ Peer-reviewed Digital health tools Mayo Clinic proceedings

    Key finding: Our results suggest that search strategies that use automated electronic search strategies to extract Charlson comorbidities from the clinical notes contained within the electronic medical record are feasible and reliable. +2 more findings

  4. 2012-09-01

    Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia

    ✓ Peer-reviewed Disparities Archives of neurology

    Key finding: Among well-functioning older adults, DM and poor glucose control among those with DM are associated with worse cognitive function and greater decline. +4 more findings

  5. 2012-09-01

    Neuropathological correlates of dopaminergic imaging in Alzheimer's disease and Lewy body dementias

    ✓ Peer-reviewed Caregiving Brain : a journal of neurology

    Key finding: Stepwise linear regression was performed to identify significant pathological predictors of striatal binding. +2 more findings

  6. 2012-09-01

    Meta-analysis of nonpharmacological interventions for neuropsychiatric symptoms of dementia

    ✓ Peer-reviewed Caregiving The American journal of psychiatry

    Key finding: The successful interventions identified included approximately nine to 12 sessions tailored to the needs of the person with dementia and the caregiver and were delivered individually in the home using multiple components over 3-6 months with periodic follow-up.

  7. 2012-09-01

    Increased cerebral metabolism after 1 year of deep brain stimulation in Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Archives of neurology

    Key finding: Increased connectivity after 1 year of DBS is observed, which is in contrast to the decreased connectivity observed over the course of AD. +1 more finding

August 2012 18

  1. 2012-08-30

    Interrelationship of oral health status, swallowing function, nutritional status, and cognitive ability with activities of daily living in Japanese elderly people receiving home care services due to physical disabilities

    ✓ Peer-reviewed Clinical safety Community dentistry and oral epidemiology

    Key finding: A lower number of teeth are positively related to swallowing dysfunction, whereas denture wearing contributes to recovery of swallowing function. +2 more findings

  2. 2012-08-30

    Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women

    ✓ Peer-reviewed TREM2 and immune genetics American journal of human genetics

    Key finding: CRP levels are higher in African Americans and Hispanic Americans than in European Americans, but the genetic determinants of CRP in these admixed United States minority populations are largely unknown. +3 more findings

  3. 2012-08-30

    Docosahexaenoic acid-concentrated fish oil supplementation in subjects with mild cognitive impairment (MCI): a 12-month randomised, double-blind, placebo-controlled trial

    ✓ Peer-reviewed Mild cognitive impairment Psychopharmacology

    Key finding: Studies with larger sample sizes, longer intervention periods, different fish oil dosages and genetic determinations should be investigated before definite recommendations can be made.

  4. 2012-08-29

    Glucagon-Like Peptide-1 Decreases Intracerebral Glucose Content by Activating Hexokinase and Changing Glucose Clearance during Hyperglycemia

    ✓ Peer-reviewed Drug development Journal of Cerebral Blood Flow & Metabolism

    Key finding: Reports indicate that glucagon-like peptide-1 (GLP-1) may be neuroprotective in models of AD and stroke: Although the mechanism is unclear, glucose homeostasis appears to be important.

  5. 2012-08-29

    Investigating structural brain changes of dehydration using voxel-based morphometry

    ✓ Peer-reviewed Mild cognitive impairment PloS one

    Key finding: A significant decrease of GM and WM volume associated with dehydration was found in various brain regions, most prominently, in temporal and sub-gyral parietal areas, in the left inferior orbito-frontal region, and in the extra-nuclear region. +2 more findings

  6. 2012-08-29

    Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

    ✓ Peer-reviewed Lewy body dementia Proceedings of the National Academy of Sciences of the United States of America

    Key finding: We show that rapamycin treatment effectively rescues the learning/memory impairment of these mice at 3 mo of age, and it significantly slows down the age-dependent loss of their motor function. +2 more findings

  7. 2012-08-28

    Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?

    ✓ Peer-reviewed Down syndrome and Alzheimer's ACS chemical neuroscience

    Key finding: The DYRK1A gene is located within the Down syndrome critical region (DSCR) on human chromosome 21 and current research suggests that overexpression of DYRK1A may be a significant factor leading to cognitive deficits in people with Alzheimer's disease (AD) and Down syndrome (DS). +2 more findings

  8. 2012-08-28

    Neuropsychiatric symptoms and global functional impairment along the Alzheimer's continuum

    ✓ Peer-reviewed Mild cognitive impairment Dementia and geriatric cognitive disorders

    Key finding: These results suggest that increased baseline hallucinations, apathy and anxiety are associated with current and future disease progression in AD. +2 more findings

  9. 2012-08-27

    Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

    Key finding: Hyper-phosphorylated-tau (p-tau) contributes to neuronal damage, and both p-tau and total-tau (t-tau) levels are elevated in AD cerebrospinal fluid (CSF) compared to cognitively normal controls. +4 more findings

  10. 2012-08-24

    Exosomal cell-to-cell transmission of alpha synuclein oligomers

    ✓ Peer-reviewed Brain tissue and pathology Molecular neurodegeneration

    Key finding: Our data suggest that αsyn may be secreted via different secretory pathways. +2 more findings

  11. 2012-08-24

    Mitochondria-associated ER membranes in Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Molecular and cellular neurosciences

    Key finding: Alzheimer disease (AD) is associated with the accumulation in the brain of extracellular neuritic plaques composed mainly of β-amyloid (Aβ) and of intracellular neurofibrillary tangles composed of hyperphosphorylated forms of the microtubule-associated protein tau. +4 more findings

  12. 2012-08-23

    Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

    ✓ Peer-reviewed Brain scans and imaging Neuropsychologia

    Key finding: Accumulating evidence suggests that subjective cognitive complaints (SCC) may indicate subtle cognitive decline characteristic of individuals with preclinical Alzheimer's disease (AD). +3 more findings

  13. 2012-08-22
  14. 2012-08-22

    Donepezil in Parkinson's disease dementia: a randomized, double-blind efficacy and safety study

    ✓ Peer-reviewed Treatments Movement disorders : official journal of the Movement Disorder Society

    Key finding: This report presents an efficacy and safety study of the acetylcholinesterase inhibitor donepezil hydrochloride in PDD. +3 more findings

  15. 2012-08-22

    Correlations of CSF tau and amyloid levels with Alzheimer pathology in neuropathologically verified dementia with Lewy bodies

    ✓ Peer-reviewed Tau biomarkers International journal of geriatric psychiatry

    Key finding: The presence of concomitant Alzheimer pathology has been linked to earlier death in cases with dementia with Lewy bodies (DLB). +3 more findings

  16. 2012-08-22

    Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: The cross-sectional difference in 2 independent neuroimaging modalities indicates early AD pathology in SMI. +1 more finding

  17. 2012-08-21

    Hyperphosphorylation of Tau induced by naturally secreted amyloid-β at nanomolar concentrations is modulated by insulin-dependent Akt-GSK3β signaling pathway

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: Although there is growing evidence for the pathogenic role of soluble Aβ species in AD, the major question of how Aβ induces hyperphosphorylation of Tau remains unanswered. +3 more findings

  18. 2012-08-20

    Advance care planning and dying in nursing homes in Flanders, Belgium: a nationwide survey

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: Prevalence of ACPs and formal authorization of a legal representative was low among the deceased NH residents in Flanders, Belgium. +1 more finding

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