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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,251–10,275 of 27,380 studies, newest first · page 411 of 1096.

May 2021 11

  1. 2021-05-04

    Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning

    ✓ Peer-reviewed Digital health tools BMC endocrine disorders

    Key finding: The study consists of 25,186 patients (mean age = 63.0, interquartile range [IQR] of age = 15.1 years, male = 50%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-05-04

    Prevalence of depression, anxiety, and apathy symptoms across dementia stages: A systematic review and meta-analysis

    ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry

    Key finding: Depression, anxiety, and apathy symptoms are highly prevalent across dementia stages. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2021-05-03

    Outdoor green space exposure and brain health measures related to Alzheimer's disease: a rapid review

    ✓ Peer-reviewed Risk factors BMJ open

    Key finding: PubMed, Embase and Web of Science Core Collection were searched for articles meeting the criteria published on/before 13 February 2020. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-05-03

    Protein and Imaging Biomarkers in the Eye for Early Detection of Alzheimer's Disease

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease reports

    Key finding: Herein, primary findings in the literature regarding AD biomarkers associated with the lens, retina, and other ocular structures are reviewed.

    Full summary, score breakdown and related studies → Original source

  5. 2021-05-02

    Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The calibrated model predicts that endogenous plaque turnover is slow, with an estimated half-life of 2.75 years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-05-02

    Spastic paraplegia preceding PSEN1-related familial Alzheimer's disease

    ✓ Peer-reviewed Risk genes beyond APOE Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: We identified a PSEN1 variant (p.Thr291Pro) in an individual presenting with pure SP at 30 years of age. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-05-01

    Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease

    ✓ Peer-reviewed Drug development Science translational medicine

    Key finding: Higher concentrations of systemic tau were observed after dosing in AD participants compared to healthy control participants.

    Full summary, score breakdown and related studies → Original source

  8. 2021-05-01

    A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis

    ✓ Peer-reviewed Biomarkers Molecular neurodegeneration

    Key finding: This mass spectrometry-based plasma biomarker test: has strong diagnostic performance; can accurately distinguish brain amyloid positive from amyloid negative individuals; may aid in the diagnostic evaluation process for Alzheimer's disease; and may enhance the efficiency of enrolling participants into Alzheimer's disease drug trials.

    Full summary, score breakdown and related studies → Original source

  9. 2021-05-01

    Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study

    ✓ Peer-reviewed Clinical safety Age and ageing

    Key finding: Delirium increases risk of future cognitive decline and dementia, independent of illness severity and baseline cognition, with more episodes associated with worse cognitive outcomes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-05-01

    Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study

    ✓ Peer-reviewed Clinical safety Age and ageing

    Key finding: Age and frailty are independently associated with adverse outcomes in COVID-19. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-05-01

    Association of Intensive vs Standard Blood Pressure Control With Magnetic Resonance Imaging Biomarkers of Alzheimer Disease: Secondary Analysis of the SPRINT MIND Randomized Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Intensive treatment was associated with a small but statistically significant greater decrease in hippocampal volume compared with standard treatment, consistent with the observation that intensive treatment is associated with greater decreases in total brain volume. +4 more findings

    Full summary, score breakdown and related studies → Original source

April 2021 14

  1. 2021-04-30

    COVID-19 and Alzheimer's disease: how one crisis worsens the other

    ✓ Peer-reviewed Clinical safety Translational neurodegeneration

    Key finding: Meanwhile, COVID-19 has also been reported to cause various neurologic symptoms including cognitive impairment that may ultimately result in AD, probably through the invasion of SARS-CoV-2 into the central nervous system, COVID-19-induced inflammation, long-term hospitalization and delirium, and post-COVID-19 syndrome.

    Full summary, score breakdown and related studies → Original source

  2. 2021-04-30

    Changes in the agreement between the Minimum Data Set and hospital Medicare claims measures of dementia

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: The agreement between the two measures of dementia differed by age: in 2017, 79.2% of hospital claims for patients aged 66–74 had a diagnosis of dementia compared to older age categories that had dementia noted in over 85% of records. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-04-30

    Novel noninvasive biomarkers of prodromal Alzheimer disease: The role of optical coherence tomography and optical coherence tomography-angiography

    ✓ Peer-reviewed Tau biomarkers European journal of neurology

    Key finding: A reduction of retinal thickness and an alteration of retinal perfusion have been found in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-04-30

    Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: CSF Aβ 42 and PiB PET showed maximal correlation when collected within 6 years of each other ( R ≈ -0.5).

    Full summary, score breakdown and related studies → Original source

  5. 2021-04-29

    Functional Brain Connectivity Patterns Associated with Visual Hallucinations in Dementia with Lewy Bodies

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease reports

    Key finding: Seed-based analyses reported decreased connectivity of the lateral geniculate nucleus, the superior parietal lobule and the putamen with the medial frontal gyrus in DLB patients with VH. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-04-29

    Four distinct trajectories of tau deposition identified in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Nature medicine

    Key finding: This spreading pattern was thought to be fairly consistent across individuals, although recent work has demonstrated substantial variability in the population with AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2021-04-29

    Nanomedicine-based technologies and novel biomarkers for the diagnosis and treatment of Alzheimer's disease: from current to future challenges

    ✓ Peer-reviewed Biomarkers Journal of nanobiotechnology

    Key finding: In this review, we investigate and describe both well-established and recently discovered AD biomarkers that could potentially be used to detect AD at early stages and allow the monitoring of disease progression. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-04-29

    Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group

    ✓ Peer-reviewed Getting a diagnosis The Lancet Neurology

    Key finding: Cognitively unimpaired individuals can have biomarker evidence of both amyloid β and tau pathology but will often not develop clinical manifestations in their lifetime. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-04-28

    Intersection between Redox Homeostasis and Autophagy: Valuable Insights into Neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Antioxidants (Basel, Switzerland)

    Key finding: In this review, we discuss recent studies on the relationship between redox homeostasis and autophagy associated with neurodegenerative diseases and propose that autophagy induction through pharmacological intervention or genetic activation might be a promising strategy to treat these disorders.

    Full summary, score breakdown and related studies → Original source

  10. 2021-04-28

    A Systematic Review and Meta-Analysis of Cognitive Training in Adults with Major Depressive Disorder

    ✓ Peer-reviewed Prevention trials Neuropsychology review

    Key finding: Despite heterogeneity, qualitative and meta-analytic synthesis of study findings revealed significant improvements in cognitive and affective outcomes following cognitive training, with moderate pooled effect sizes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2021-04-28

    Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy

    ✓ Peer-reviewed Inflammation and the immune system Nature

    Key finding: Although there is no effective treatment for AD, passive immunotherapy with monoclonal antibodies against amyloid beta (Aβ) is a promising therapeutic strategy 2,3 . +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-04-27

    Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients

    ✓ Peer-reviewed Genetics Cell stem cell

    Key finding: Mapping iNs to longitudinal neuronal differentiation trajectory data demonstrated that AD iNs reflect a hypo-mature neuronal identity characterized by markers of stress, cell cycle, and de-differentiation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-04-27

    Role of ABCA7 in Human Health and in Alzheimer's Disease

    ✓ Peer-reviewed Genetics International journal of molecular sciences

    Key finding: Several studies, including genome wide association studies (GWAS), have strongly suggested a central role for the ATP-binding cassette transporter subfamily A member 7 (ABCA7) in Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-04-26

    Ambient fine particulate matter exposure and incident mild cognitive impairment and dementia

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: Modeling estimated single-year exposure, each 1 μg/m3 higher ambient PM2.5 was associated with 67% higher adjusted risk of incident dementia (hazard ratio [HR] = 1.669, 95% credible interval [CI]: 1.298, 2.136) and 75% higher adjusted risk of incident MCI (HR = 1.746, 95% CI: 1.518, 2.032). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →