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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 25,251–25,275 of 27,380 studies, newest first · page 1011 of 1096.

February 2001 3

  1. 2001-02-01

    Prevalence of Alzheimer's disease, vascular dementia and dementia with Lewy bodies in a Japanese population

    ✓ Peer-reviewed Disparities Psychiatry and clinical neurosciences

    Key finding: The overall prevalence was higher in women for AD, while that of VD was the same in both sexes. +1 more finding

  2. 2001-02-01

    A randomized, controlled trial of a home environmental intervention: effect on efficacy and upset in caregivers and on daily function of persons with dementia

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Purpose of study The authors determined short-term effects of a home environmental intervention on self-efficacy and upset in caregivers and daily function of dementia patients.

  3. 2001-02-01

    Astrocytic clasmatodendrosis in hippocampal organ culture

    ✓ Peer-reviewed Biomarkers Glia

    Key finding: More than 90 years ago Alzheimer showed that astrocytes lose their distal processes (i.e., undergo "clasmatodendrosis") when irreversibly injured by a reduction in blood flow, a process shown by Friede and van Houten (1961) to be due to energy failure and acidosis. +2 more findings

January 2001 22

  1. 2001-01-10

    Evidence for a partially folded intermediate in alpha-synuclein fibril formation

    ✓ Peer-reviewed Brain tissue and pathology The Journal of biological chemistry

    Key finding: This raises the question of how an essentially disordered protein is transformed into highly organized fibrils. +4 more findings

  2. 2001-01-09

    Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan

    ✓ Peer-reviewed Disparities Neurology

    The incidence rate for AD was significantly higher among African-American and Caribbean Hispanic elderly individuals compared white individuals.

  3. 2001-01-01

    CRMP-5 neuronal autoantibody: Marker of lung cancer and thymoma-related autoimmunity

    ✓ Peer-reviewed Disease mechanisms Annals of Neurology

    Key finding: Clinical information, obtained for 116 patients, revealed multifocal neurological signs. +1 more finding

  4. 2001-01-01

    Pericytes: Cell Biology and Pathology

    ✓ Peer-reviewed Vascular contributions Cells Tissues Organs

    Key finding: The coverage of EC by pericytes varies considerably between different microvessel types and the location of pericytes on the microvessel is not random but appears to be functionally determined. +4 more findings

  5. 2001 year only

    Late life depression

    ✓ Peer-reviewed Risk factors European archives of psychiatry and clinical neuroscience

    Key finding: Depression has an overall prevalence of 5-8%. +2 more findings

  6. 2001 year only

    Economic evaluations during early (phase II) drug development: a role for clinical trial simulations?

    ✓ Peer-reviewed Clinical trials PharmacoEconomics

    Key finding: The results demonstrate how the modelling may be of value in 'go/no-go' decisions during the drug development programme.

  7. 2001 year only

    Tacrine and rate of progression in Alzheimer's disease--relation to ApoE allele genotype

    ✓ Peer-reviewed Genetics Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: No differences were found after 6 months of treatment, but after 12 months the CIBIC scores revealed that the ApoE4 patients had declined more than the ApoE2-3 patients (p < 0.05). +1 more finding

  8. 2001-01-01

    Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: Compared with control subjects (CDR = 0), mild (early) AD (CDR = 0.5 to 1) cases had a 25% loss of synaptophysin immunoreactivity.

  9. 2001-01-01

    Down syndrome and Alzheimer's disease: a link between development and aging

    ✓ Peer-reviewed Down syndrome and Alzheimer's Mental retardation and developmental disabilities research reviews

    Key finding: A review of the existing literature indicates that oxidative damage and neuroinflammation may interact to accelerate the disease process particularly in individuals with DS over the age of 40 years.

  10. 2001-01-01
  11. 2001-01-01

    Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments

    ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry

    Key finding: BPSD are common in elderly people with dementia living in care environments. +1 more finding

  12. 2001-01-01

    Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

    ✓ Peer-reviewed Inflammation and the immune system Drugs & aging

    Key finding: Indeed, it has been shown that proteasomal inhibition increases levels of oxidative damage not only to proteins but also to other biomolecules.

  13. 2001-01-01

    A new therapeutic target in Alzheimer's disease treatment: attention to butyrylcholinesterase

    ✓ Peer-reviewed Treatments Current medical research and opinion

    Key finding: Recent evidence suggests that BuChE may also have a role in the aetiology and progression of AD beyond regulation of synaptic ACh levels.

  14. 2001-01-01

    Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

    ✓ Peer-reviewed Risk genes beyond APOE The EMBO journal

    Key finding: Our results demonstrate that in vivo overexpression of GSK-3beta results in neurodegeneration and suggest that these mice can be used as an animal model to study the relevance of GSK-3beta deregulation to the pathogenesis of Alzheimer's disease.

  15. 2001-01-01

    Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: We describe a novel class of compounds that reduce A beta production by functionally inhibiting gamma-secretase, the activity responsible for the carboxy-terminal cleavage required for A beta production. +4 more findings

  16. 2001-01-01

    Protein oxidation in the brain in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Neuroscience

    Key finding: In two brain regions severely affected by Alzheimer's disease pathology, prominent protein carbonyl immunoreactivity was localized in the cytoplasm of neurons without visual pathomorphological changes and degenerating neurons, suggesting that intracellular proteins might be significantly affected by oxidative modifications. +3 more findings

  17. 2001-01-01

    Biology of posttraumatic stress disorder

    ✓ Peer-reviewed Hippocampus size on brain scans The Journal of clinical psychiatry

    Key finding: However, over the last 10 years, biological observations have been made in PTSD that are different from what has been typically associated with chronic stress, notably certain hypothalamic-pituitary-adrenal (HPA) axis findings. +2 more findings

  18. 2001-01-01

    Neuroimaging studies of the hippocampus in schizophrenia

    ✓ Peer-reviewed Hippocampus size on brain scans Hippocampus

    Key finding: Functional neuroimaging studies have demonstrated abnormal levels of hippocampal activity at rest, during the experience of auditory hallucinations, and during the performance of memory retrieval tasks. +1 more finding

  19. 2001-01-01

    Ethnicity and end-of-life care: the use of feeding tubes

    ✓ Peer-reviewed End-of-life care Ethnicity & disease

    Key finding: Feeding tube use is significantly more common in Blacks than in Whites. +4 more findings

  20. 2001-01-01

    Family caregiving in hospice: effects on psychological and health functioning among spousal caregivers of hospice patients with lung cancer or dementia

    ✓ Peer-reviewed End-of-life care The Hospice journal

    Key finding: Hospice family caregivers are at high risk for both psychological and physical health disorders, and caregiver depression and health problems should be systematically assessed and treated by the hospice team. +3 more findings

  21. 2001-01-01

    Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro

    ✓ Peer-reviewed Inflammation and the immune system Neuroscience

    Key finding: Morphine (10nM, 100nM or 1microM) significantly increased Tat-induced (100 or 200nM) neuronal losses by about two-fold at 24h following exposure. +1 more finding

  22. 2001 no date recorded — placed by publication year

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