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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,976–12,000 of 27,380 studies, newest first · page 480 of 1096.

January 2020 25

  1. 2020-01-21

    Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment

    ✓ Peer-reviewed Risk factors Journal of clinical medicine

    Key finding: Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent upper airway obstruction during sleep resulting in intermittent hypoxemia and sleep fragmentation. +2 more findings

  2. 2020-01-21

    Liraglutide improves memory in obese patients with prediabetes or early type 2 diabetes: a randomized, controlled study

    ✓ Peer-reviewed Drug development International journal of obesity (2005)

    Key finding: Liraglutide might slow down memory function decline in diabetic patients in early, and possibly preclinical stages of the disease. +1 more finding

  3. 2020-01-21

    Road proximity, air pollution, noise, green space and neurologic disease incidence: a population-based cohort study

    ✓ Peer-reviewed Disparities Environmental health : a global access science source

    Key finding: This association may be partially mediated by air pollution, whereas noise exposure did not affect associations.

  4. 2020-01-21

    Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: A faster termination of the stress response (higher coping ability) may limit the negative effects of stress on tau deposition. +4 more findings

  5. 2020-01-20

    The novel GLP‐1/GIP analogue DA5‐CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD

    ✓ Peer-reviewed Drug development Brain and Behavior

    Key finding: Our results demonstrate that DA5‐CH has neuroprotective effects in the STZ‐induced animal model and that DA5‐CH has potential to treat neurodegenerative disorders such as AD. +3 more findings

  6. 2020-01-20

    Review of Alterations in Perlecan-Associated Vascular Risk Factors in Dementia

    ✓ Peer-reviewed Vascular contributions International journal of molecular sciences

    Key finding: VCID, a comorbidity with diverse etiology in sporadic Alzheimer's disease (AD), is thought to be a major factor that drives the overall clinical burden of dementia.

  7. 2020-01-20

    An Altered Relationship between Soluble TREM2 and Inflammatory Markers in Young Adults with Down Syndrome: A Preliminary Report

    ✓ Peer-reviewed TREM2 and immune genetics Journal of immunology (Baltimore, Md. : 1950)

    Key finding: Because TREM2 plays a role in the innate immune response and has been associated with dementia, the hypothesis of this exploratory study was that young adults with DS predementia ( n = 15, mean age = 29.5 y) would exhibit a different relationship between sTREM2 and inflammatory markers in plasma, compared with neurotypical, age-matched controls ( n = 16, mean age = 29.6 y). +2 more findings

  8. 2020-01-20

    Comparing food desert residents with non-food desert residents on grocery shopping behaviours, diet and BMI: results from a propensity score analysis

    ✓ Peer-reviewed Risk factors Public Health Nutrition

    Key finding: Residence in a food desert (11·1 %, n 411) was not significantly associated with perceived access to healthy foods, most grocery shopping behaviours or dietary behaviour, but was significantly associated with primarily shopping at a superstore or supercentre v . a large grocery store (OR = 1·32; 95 +1 more finding

  9. 2020-01-19

    Validity, reliability, and psychometric properties of a computerized, cognitive assessment test (Cognivue ® )

    ✓ Peer-reviewed Cognitive tests and assessment World journal of psychiatry

    Key finding: Cognivue ® scores ≤ 50 avoid misclassification of impairment, and scores ≥ 75 avoid misclassification of unimpairment. +2 more findings

  10. 2020-01-18

    Autophagy modulates Aβ accumulation and formation of aggregates in yeast

    ✓ Peer-reviewed Disease mechanisms Molecular and cellular neurosciences

    Key finding: Overall, our findings identify a novel role for these nutrient and stress signalling genes in the targeted elimination of Aβ42 aggregates, which offer a promising avenue for developing autophagy based therapies to suppress amyloid deposition in AD.

  11. 2020-01-18

    Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus

    ✓ Peer-reviewed Risk factors Trends in molecular medicine

    Key finding: Approximately 10% of dementia patients have idiopathic normal pressure hydrocephalus (iNPH), an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and Alzheimer's disease (AD) both exhibit sleep disturbances, build-up of brain metabolic wastes and amyloid-β (Aβ) plaques, perivascular reactive astrogliosis, and mislocalization of astrocyte aquaporin-4 (AQP4). +3 more findings

  12. 2020-01-17

    Temporal and anatomical distribution of 18F-flutemetamol uptake in canine brain using positron emission tomography

    ✓ Peer-reviewed Brain scans and imaging BMC veterinary research

    Key finding: Among the six cerebral cortical regions, the cingulate cortices and frontal lobe showed the highest SUVRs. +4 more findings

  13. 2020-01-17

    The progress of gut microbiome research related to brain disorders

    ✓ Peer-reviewed Disease mechanisms Journal of neuroinflammation

    Key finding: However, it is now becoming clear that many non-nervous system factors, including the gut-resident bacteria of the gastrointestinal tract, regulate and influence cognitive dysfunction as well as the process of neurodegeneration and cerebrovascular diseases. +4 more findings

  14. 2020-01-17

    Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Nature communications

    Key finding: In Alzheimer's diseases (AD), tau pathology is strongly associated with cognitive decline. +4 more findings

  15. 2020-01-17

    The characterisation of subjective cognitive decline

    ✓ Peer-reviewed Mild cognitive impairment The Lancet Neurology

    Key finding: The term subjective cognitive decline (SCD) was conceived in 2014 to describe cognitively unimpaired individuals who are concerned that they have reduced cognitive function. +2 more findings

  16. 2020-01-17

    Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in pharmacology

    Key finding: The aim of this study was to investigate its effects on the behavioral performance of lipopolysaccharide (LPS)-challenged rats and explore the potential mechanism. +3 more findings

  17. 2020-01-17

    The Effect of Hearing Aid Use on Cognition in Older Adults: Can We Delay Decline or Even Improve Cognitive Function?

    ✓ Peer-reviewed Digital health tools Journal of clinical medicine

    Key finding: At baseline, multiple linear regression showed hearing loss and age predicted significantly poorer executive function performance, while tertiary education predicted significantly higher executive function and visual learning performance. +4 more findings

  18. 2020-01-17

    Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology

    ✓ Peer-reviewed Genetics EMBO molecular medicine

    Key finding: We identify in this module 7 established AD risk genes (APOE, CLU, INPP5D, CD33, PLCG2, SPI1, and FCER1G) and 11 AD GWAS genes below the genome-wide significance threshold (GPC2, TREML2, SYK, GRN, SLC2A5, SAMSN1, PYDC1, HEXB, RRBP1, LYN, and BLNK), that become significantly upregulated when exposed to Aβ. +1 more finding

  19. 2020-01-16

    Stratifying risk for dementia onset using large-scale electronic health record data: A retrospective cohort study

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: A cognitive symptom measure identified in discharge notes facilitated stratification of risk for dementia up to 8 years before diagnosis. +2 more findings

  20. 2020-01-16

    Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Principle component analyses identified 3 factors: trophic (BDNF, VEGF, TGFβ), degenerative (GFAP, NfL), and inflammatory (TNFα, IL-6, IP-10, IL-10). +4 more findings

  21. 2020-01-16

    Systematic review of genetic association studies in people with Lewy body dementia

    ✓ Peer-reviewed TREM2 and immune genetics International journal of geriatric psychiatry

    Key finding: Eight thousand five hundred twenty-one articles were screened, and 75 articles were eligible to be included. +1 more finding

  22. 2020-01-16

    Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This clinical trial evaluates the efficacy and safety of a 6-week course of daily neuroAD™ therapy. +3 more findings

  23. 2020-01-16

    Choroid plexus volume is associated with levels of CSF proteins: relevance for Alzheimer's and Parkinson's disease

    ✓ Peer-reviewed Mild cognitive impairment Neurobiology of aging

    Key finding: We found negative associations between ChP volume and CSF proteins, which were stronger in healthy controls, early-MCI patients, and PD patients compared with late-MCI and AD patients. +2 more findings

  24. 2020-01-15

    Polysomnographic assessment of suvorexant in patients with probable Alzheimer's disease dementia and insomnia: a randomized trial

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Of 285 participants randomized (suvorexant, N = 142; placebo, N = 143), 277 (97%) completed the trial (suvorexant, N = 136; placebo, N = 141). +3 more findings

  25. 2020-01-14

    TDP-43 and Limbic-Predominant Age-Related TDP-43 Encephalopathy

    ✓ Peer-reviewed Brain tissue and pathology Frontiers in aging neuroscience

    Key finding: LATE is perhaps best characterized by the presence of hyperphosphorylated TDP-43, which plays multi-functional roles through interactions with DNA and RNA, leading to significant alterations in the transcription and translation of particular genes.

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