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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,851–11,875 of 27,380 studies, newest first · page 475 of 1096.

March 2020 20

  1. 2020-03-02

    Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression

    ✓ Peer-reviewed Risk factors The lancet. Diabetes & endocrinology

    Key finding: Adults with type 2 diabetes are at an increased risk of developing certain brain or mental disorders, including stroke, dementia, and depression. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-03-02

    Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia

    ✓ Peer-reviewed Getting a diagnosis Nature medicine

    Key finding: High plasma P-tau181 was associated with subsequent development of AD dementia in cognitively unimpaired and MCI subjects. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2020-03-01

    Spinosin Attenuates Alzheimer's Disease-Associated Synaptic Dysfunction via Regulation of Plasmin Activity

    ✓ Peer-reviewed Disease mechanisms Biomolecules & therapeutics

    Key finding: These results suggest that spinosin improves synaptic function in the AD hippocampus by regulating plasmin activity.

    Full summary, score breakdown and related studies → Original source

  4. 2020-03-01

    Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations

    ✓ Peer-reviewed Brain tissue and pathology Journal of neuropathology and experimental neurology

    Key finding: The present study aimed to investigate potential risk factors and neuropathological characteristics associated with LATE-NC. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-03-01

    Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD

    ✓ Peer-reviewed Brain tissue and pathology Journal of neuropathology and experimental neurology

    Key finding: In PSP, FTD-Tau, independent of copathology, associated with executive, language, motor, and visuospatial impairments, while PSP with Parkinsonism had a lower FTD-Tau burden, but this was not the case in CBD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2020-03 month only

    [Hearing and cognition: neurocognitive test batteries in otorhinolaryngology]

    ✓ Peer-reviewed Risk factors HNO

    Key finding: A multitude of different neurocognitive screening tests and detailed test batteries are available, particularly in the field of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-03 month only

    Lemborexant: First Approval

    ✓ Peer-reviewed Risk factors Drugs

    Key finding: It is also being investigated for the treatment of irregular sleep-wake rhythm disorder (ISWRD) associated with mild to moderate Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  8. 2020-03 month only

    Developing robust biomarkers for vascular cognitive disorders: adding 'V' to the AT(N) research framework

    ✓ Peer-reviewed Brain scans and imaging Current opinion in psychiatry

    Key finding: The AT(N) research framework was introduced in 2018 to define Alzheimer's disease as a biological entity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2020-03-01

    Association of Physician Orders for Life-Sustaining Treatment With ICU Admission Among Patients Hospitalized Near the End of Life

    ✓ Peer-reviewed End-of-life care JAMA

    Key finding: For evaluating factors associated with POLST-discordant care, the outcome was ICU admission contrary to POLST order for medical interventions during the last hospitalization of life. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-03-01

    US Health Care Spending by Payer and Health Condition, 1996-2016

    ✓ Peer-reviewed Risk factors JAMA

    Key finding: Total health care spending increased from an estimated $1.4 trillion in 1996 (13.3% of gross domestic product [GDP]; $5259 per person) to an estimated $3.1 trillion in 2016 (17.9% of GDP; $9655 per person); 85.2% of that spending was included in this study.

    Full summary, score breakdown and related studies → Original source

  11. 2020-03-01

    Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: We found significant group-wise differences in 11C-PK-11195 binding between each patient group and controls in frontotemporal regions, in both a regions-of-interest analysis and in the comparison of principal spatial components of binding. 18F-AV-1451 binding was increased in semantic variant primary progressive aphasia compared to controls in the temporal regions, and both semantic variant primary progressive aphasia and behavioural variant frontotemporal dementia differed from controls in the expression of principal spatial components of binding, across temporal and frontotemporal cortex, respectively. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2020-03-01

    Hospital Transfer Rates Among US Nursing Home Residents With Advanced Illness Before and After Initiatives to Reduce Hospitalizations

    ✓ Peer-reviewed End-of-life care JAMA internal medicine

    Key finding: The findings of this study suggest that concurrent with new initiatives aimed at reducing hospitalizations, hospital transfers declined between 2011 and 2017 among nursing home residents with advanced illnesses without increased mortality rates. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2020-03-01

    Computerized Cognitive Training for Older Adults at Higher Dementia Risk due to Diabetes: Findings From a Randomized Controlled Trial

    ✓ Peer-reviewed Prevention trials The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Our findings suggest that older adults at higher dementia risk due to diabetes can show improvements in both cognition and disease self-management following home-based multidomain computerized cognitive training. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-03-01

    A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

    ✓ Peer-reviewed Tau biomarkers Nature Medicine

    Key finding: We identified a pattern of tau staging where site-specific phosphorylation changes occur at different periods of disease progression and follow distinct trajectories over time. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-03-01

    Neuroimaging in the Diagnosis of Chronic Traumatic Encephalopathy: A Systematic Review

    ✓ Peer-reviewed Disease mechanisms Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

    Key finding: Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repeated subconcussive and concussive head injury. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-03-01

    Association of Intracranial Atherosclerotic Disease With Brain β-Amyloid Deposition: Secondary Analysis of the ARIC Study

    ✓ Peer-reviewed Long-term cohort studies JAMA neurology

    Key finding: Intracranial atherosclerotic disease (ICAD) is an important cause of stroke and has also been recently identified as an important risk factor for all-cause dementia, but the mechanism of its association with cognitive performance is not fully understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-03-01

    Assessing Risks of Polypharmacy Involving Medications With Anticholinergic Properties

    ✓ Peer-reviewed Long-term cohort studies Annals of family medicine

    Key finding: Anticholinergic burden (ACB), the cumulative effect of anticholinergic medications, is associated with adverse outcomes in older people but is less studied in middle-aged populations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020-03-01

    Soluble TREM2 is elevated in Parkinson's disease subgroups with increased CSF tau

    ✓ Peer-reviewed TREM2 and immune genetics Brain : a journal of neurology

    Key finding: Although Parkinson's disease commonly manifests with motor symptoms, a majority of patients with Parkinson's disease subsequently develop cognitive impairment, which often progresses to dementia, a major cause of morbidity and disability. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020-03-01

    Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation

    ✓ Peer-reviewed Risk genes beyond APOE Cell reports

    Key finding: Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020-03-01

    Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Patients in the CBS-AD group had a longer diagnostic latency, relatively benign clinical trajectory, greater cognitive impairment, and higher APOE-ε4 allele frequency than those in the CBS-non-AD group (AUC, 0.80-0.87; P Conclusions and relevance These findings suggest that studies focusing on the PSP-RS subtype are likely to miss a large number of patients with underlying PSP tau pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

February 2020 5

  1. 2020-02-29

    Current and Future Treatments in Alzheimer Disease: An Update

    ✓ Peer-reviewed Treatments Journal of central nervous system disease

    Key finding: To block the progression of the disease, therapeutic agents are supposed to interfere with the pathogenic steps responsible for the clinical symptoms, classically including the deposition of extracellular amyloid β plaques and intracellular neurofibrillary tangle formation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-02-29

    Hippocampal atrophy based Alzheimer's disease diagnosis via machine learning methods

    ✓ Peer-reviewed Digital health tools Journal of neuroscience methods

    Key finding: By using this approach, we conclude that brain MRIs can be used to distinguish the patients with Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) and Cognitive Normal (CN) from each other; while most of the studies were only able to distinguish AD from CN. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2020-02-28

    TDP-43: From Alzheimer's Disease to Limbic-Predominant Age-Related TDP-43 Encephalopathy

    ✓ Peer-reviewed Brain tissue and pathology Frontiers in molecular neuroscience

    Key finding: Because AD is complex and heterogeneous, and because of the distinct characteristics of TDP-43, mostly seen in the oldest-old and those with more severe clinical phenotype, subcategorization based on specific features or biomarkers may significantly improve diagnosis and treatment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2020-02-28

    The multiplex model of the genetics of Alzheimer's disease

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: Over 50 loci are now implicated for AD, suggesting that AD is a disease of multiple components, as supported by pathway analyses (immunity, endocytosis, cholesterol transport, ubiquitination, amyloid-β and tau processing). +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2020-02-27

    Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life

    ✓ Peer-reviewed Prevention trials The Cochrane database of systematic reviews

    Key finding: We found no data on our primary outcome of global cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →