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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,076–12,100 of 27,380 studies, newest first · page 484 of 1096.

January 2020 25

  1. 2020 year only

    Digital Biomarkers Based Individualized Prognosis for People at Risk of Dementia: the AltoidaML Multi-site External Validation Study

    ✓ Peer-reviewed Cognitive tests and assessment Advances in experimental medicine and biology

    Key finding: Although some biological measures (biomarkers) can identify Alzheimer's-related changes before significant changes in cognitive function occur, such biomarkers are not ideal as they are only able to place individuals in rudimentary stages of the disease/cognitive decline (Tarnanas et al., Alzheimers Dement (Amst) 1(4):521-532, 2015) and sometimes mistakenly diagnose individuals (Edmonds et al. 2015).

    Full summary, score breakdown and related studies → Original source

  2. 2020 year only

    Cerebrospinal Fluid Biomarkers to Differentiate Idiopathic Normal Pressure Hydrocephalus from Subcortical Ischemic Vascular Disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Lower levels of NFL, NG, Aβ42, and t-tau were found in patients with iNPH versus SIVD, while YKL-40 and p-tau were similar in the two diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020 year only

    Increased Cerebrospinal Fluid Concentration of ZnT3 Is Associated with Cognitive Impairment in Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: We found a significant increase in the concentrations of ZnT3, GluA3, and Dynamin1 in AD (p = 0.002) and of ZnT3 and Dynamin 1 in DLB (p = 0.001, p = 0.002) when compared to SCD patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020 year only

    Cerebrospinal Fluid and MRI Biomarkers in Neurodegenerative Diseases: A Retrospective Memory Clinic-Based Study

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Numerous imaging variables differed by clinical diagnosis, including hippocampal, amygdalar and inferior lateral ventricular volumes and entorhinal, lingual, inferior parietal and isthmus cingulate cortical thicknesses, at a false discovery rate (FDR)-corrected threshold for significance (analysis of covariance; p < 0.005). +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020 year only

    Challenges in Alzheimer's Disease Diagnostic Work-Up: Amyloid Biomarker Incongruences

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: CSF AβR better agreed with Amy-PET compared to CSF Aβ42 (Cohen's K 0.431 versus 0.05). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-01 month only

    Concordance of Lumipulse cerebrospinal fluid t-tau/Aβ42 ratio with amyloid PET status

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Virtually identical t-tau/Aβ42 cut-points (∼0.54) performed best in both test cohorts and with similar accuracy (areas under ROC curve [AUCs] [A/B: 0.95; C: 0.94]). +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020 year only

    Amyloid Metabolism and Amyloid-Targeting Blood-Based Biomarkers of Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Although there has been extensive research on the metabolism of Aβ in AD, new compelling results have recently emerged. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020 year only

    Pre-Analytical Sampling and Storage Conditions of Amyloid-β Peptides in Venous and Capillary Blood

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: This study shows that Aβ40, Aβ42, and Aβ42/40 levels significantly and early decrease during storage at room temperature in whole blood or plasma.

    Full summary, score breakdown and related studies → Original source

  9. 2020 year only

    Plasma Neurofilament Light and Longitudinal Progression of White Matter Hyperintensity in Elderly Persons Without Dementia

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Longitudinal analyses showed that higher baseline plasma NFL concentration was associated with accelerated progression of WMH (β=0.015, p = 0.007). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2020 year only

    Plasma Neurofilament Light: A Marker of Neurodegeneration in Mild Behavioral Impairment

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Time*MBI status was the only significant interaction to predict change in NfL concentrations (F(1,574) = 4.59, p = 0.032), even after controlling for age, mild cognitive impairment, and demographics. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-01-01

    Artificial Intelligence, Speech, and Language Processing Approaches to Monitoring Alzheimer's Disease: A Systematic Review

    ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD

    Key finding: Promising results are reported across nearly all 51 studies, but very few have been implemented in clinical research or practice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-01-01

    Clinical and Bacterial Markers of Periodontitis and Their Association with Incident All-Cause and Alzheimer's Disease Dementia in a Large National Survey

    ✓ Peer-reviewed Costs and economics Journal of Alzheimer's disease : JAD

    Key finding: Among those ≥65 years, AD incidence and mortality were consistently associated with PPD, two factors and one cluster comprised of IgG titers against Porphyromonas gingivalis (P. gingivalis), Prevotella melaninogenica (P. melaninogenica) and Campylobacter rectus (C. rectus) among others.

    Full summary, score breakdown and related studies → Original source

  13. 2020-01-01

    Air Pollution and Alzheimer's Disease: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Air pollution exposure may exacerbate AD development. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-01-01

    Heavy Metals Exposure and Alzheimer's Disease and Related Dementias

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Lead and cadmium are associated with numerous health outcomes even at low levels of exposure. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2020-01-01

    Neurobiology of COVID-19

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: There remains a challenge to determine the extent to which neurological abnormalities in COVID-19 are caused by SARS-Cov2 itself, the exaggerated cytokine response it triggers, and/or the resulting hypercoagulapathy and formation of blood clots in blood vessels throughout the body and the brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-01-01

    The Dual GLP-1/GIP Receptor Agonist DA4-JC Shows Superior Protective Properties Compared to the GLP-1 Analogue Liraglutide in the APP/PS1 Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed Drug development American journal of Alzheimer's disease and other dementias

    Key finding: The results suggest that DA4-JC may be a novel treatment for AD.

    Full summary, score breakdown and related studies → Original source

  17. 2020-01-01

    Antidiabetic Drugs for the Risk of Alzheimer Disease in Patients With Type 2 DM Using FAERS

    ✓ Peer-reviewed Drug development American journal of Alzheimer's disease and other dementias

    Key finding: The risk of AD from the use of different antidiabetic drug monotherapies compared to that of metformin monotherapy was assessed by logistic regression. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2020-01-01

    Vildagliptin Attenuates Huntington's Disease through Activation of GLP-1 Receptor/PI3K/Akt/BDNF Pathway in 3-Nitropropionic Acid Rat Model

    ✓ Peer-reviewed Drug development Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

    Key finding: In conclusion, Vilda purveyed significant anti-Huntington effect which may be mediated, at least in part, via activation of GLP-1/PI3K/Akt pathway in 3NP rat model.

    Full summary, score breakdown and related studies → Original source

  19. 2020-01-01

    Safety, Tolerability, and Pharmacokinetics of Crenezumab in Patients with Mild-to-Moderate Alzheimer's Disease Treated with Escalating Doses for up to 133 Weeks

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Crenezumab doses of ≤120 mg/kg intravenously q4w were well tolerated.

    Full summary, score breakdown and related studies → Original source

  20. 2020-01-01

    The Future of Anti-Amyloid Trials

    ✓ Peer-reviewed Treatments The journal of prevention of Alzheimer's disease

    Key finding: Studies suggest that Amyloid-Related Imaging Abnormalities - effusion type (ARIA-E) are a manageable safety concern and that caution should be exercised before terminating studies based on interim analyses. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2020-01-01

    Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer's Disease

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: We report a novel association between gut microbiota-related products and systemic inflammation with brain amyloidosis via endothelial dysfunction, suggesting that SCFAs and LPS represent candidate pathophysiologic links between the gut microbiota and AD pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2020-01-01

    Mild behavioral impairment is associated with β-amyloid but not tau or neurodegeneration in cognitively intact elderly individuals

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We demonstrate for the first time a link between MBI and early AD pathology in a cognitively intact elderly population, supporting the use of the MBI-C as a metric to enhance clinical trial enrolment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020-01-01

    Amyloid and tau imaging biomarkers explain cognitive decline from late middle-age

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: A significant group × age interaction was observed with post hoc comparisons indicating that the group with both elevated amyloid and tau pathophysiology were declining approximately three times faster in retrospective cognition compared to those with just one or no elevated biomarkers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-01-01

    Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET

    ✓ Peer-reviewed Brain scans and imaging Science translational medicine

    Key finding: Quantitative analyses showed that the global intensity of tau-PET, but not β-amyloid-PET, signal predicted the rate of subsequent atrophy, independent of baseline cortical thickness. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2020-01-01

    Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia

    ✓ Peer-reviewed Genetics Brain : a journal of neurology

    Key finding: Variants in GBA, encoding the enzyme glucocerebrosidase, are associated with Lewy body diseases such as Parkinson's disease and Lewy body dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →