alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 12,351–12,375 of 27,380 studies, newest first · page 495 of 1096.

November 2019 7

  1. 2019-11-01

    Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline

    ✓ Peer-reviewed Long-term cohort studies Journal of the American Geriatrics Society

    Key finding: Understanding how dementia risk is impacted by timing of smoking cessation has public health implications for prevention efforts. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2019-11-01

    Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging

    ✓ Peer-reviewed Tau biomarkers JAMA neurology

    Key finding: Blood biomarkers able to diagnose Alzheimer disease (AD) at the preclinical stage would enable trial enrollment when the disease is potentially reversible. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2019-11-01

    A Framework of Minority Stress: From Physiological Manifestations to Cognitive Outcomes

    ✓ Peer-reviewed Disparities The Gerontologist

    Key finding: Specifically, black persons in the United States are more likely to live with social conditions that affect their stress levels which in turn affect physiological regulation leading to conditions that result in higher levels of cognitive impairment or dementia.

    Full summary, score breakdown and related studies → Original source

  4. 2019-11-01

    Burden of Cause-Specific Mortality Associated With PM2.5 Air Pollution in the United States

    ✓ Peer-reviewed Prevention and risk JAMA network open

    Key finding: A cohort of 4 522 160 US veterans (4 243 462 [93.8%] male; median [interquartile range] age, 64.1 [55.7-75.5] years; 3 702 942 [82.0%] white, 667 550 [14.8%] black, and 145 593 [3.2%] other race) was followed up for a median (interquartile range) of 10.0 (6.8-10.2) years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-11-01

    The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer's Disease-A Review

    ✓ Peer-reviewed Prevention and risk Advances in nutrition (Bethesda, Md.)

    Key finding: A systematic search was conducted within Ovid Medline for studies published up to 27 March 2019 and reference lists from existing reviews and select articles were examined to supplement the electronic search results. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-11-01

    Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: Of 482 participants in the safety population, 140 of 158 participants (88.6%) assigned to placebo, 117 of 166 participants (70.5%) to 224 mg of edonerpic maleate, and 120 of 158 participants (76.0%) to 448 mg of edonerpic maleate completed the trial.

    Full summary, score breakdown and related studies → Original source

  7. 2019-11-01

    Staging β-Amyloid Pathology With Amyloid Positron Emission Tomography

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Among 641 participants with CSF Aβ42 data and at least two 18F-florbetapir scans, 335 (52.3%) were male. +3 more findings

    Full summary, score breakdown and related studies → Original source

October 2019 18

  1. 2019-10-31

    From EST to structure models for functional inference of APP, BACE1, PSEN1, PSEN2 genes

    ✓ Peer-reviewed Risk genes beyond APOE Bioinformation

    Key finding: Successive oxidative stress and biochemical changes results in neuronal death and neuritic plaques growth in Alzheimer's disease (AD).

    Full summary, score breakdown and related studies → Original source

  2. 2019-10-31

    Individualized clinical management of patients at risk for Alzheimer's dementia

    ✓ Peer-reviewed Prevention trials Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Individualized multidomain interventions may improve cognition and reduce AD/cardiovascular risk scores in patients at-risk for AD dementia.

    Full summary, score breakdown and related studies → Original source

  3. 2019-10-31

    ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components

    ✓ Peer-reviewed Genetics Arteriosclerosis, thrombosis, and vascular biology

    Key finding: ApoE4 impairs pericyte-mediated basement membrane formation, potentially contributing to the cerebrovascular effects of apoE4. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-10-31

    Amyloid PET, FDG-PET or MRI? - the power of different imaging biomarkers to detect progression of early Alzheimer's disease

    ✓ Peer-reviewed Biomarkers BMC neurology

    Key finding: Amyloid imaging with PET and measuring cortical thickness with MRI are suitable biomarkers to detect disease progression in early AD within a small sample. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2019-10-30

    CRISPR/Cas13a-Powered Electrochemical Microfluidic Biosensor for Nucleic Acid Amplification-Free miRNA Diagnostics

    ✓ Peer-reviewed Getting a diagnosis Advanced materials (Deerfield Beach, Fla.)

    Key finding: A dysregulation of these microRNAs can be associated with many different diseases, such as cancer, dementia, and cardiovascular conditions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2019-10-29

    Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue

    ✓ Peer-reviewed Vascular contributions Nature communications

    Key finding: However, the structure of Aβ amyloid fibrils from brain tissue is poorly understood. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-10-29

    Fewer patients undergo surgery when adding a comprehensive geriatric assessment in older patients with a hip fracture

    ✓ Peer-reviewed End-of-life care Archives of orthopaedic and trauma surgery

    Key finding: The geriatrician can have an important role in decisions for non-surgical management by shared decision making in the pre-operative period in patients ≥ 70 years with a hip fracture in the emergency room.

    Full summary, score breakdown and related studies → Original source

  8. 2019-10-29

    Distributed Patterns of Functional Connectivity Predict Working Memory Performance in Novel Healthy and Memory-impaired Individuals

    ✓ Peer-reviewed Brain scans and imaging Journal of cognitive neuroscience

    Key finding: Using n -back or rest data from the Human Connectome Project, connectome-based predictive models significantly predicted novel individuals' 2-back accuracy. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2019-10-28

    Secular trends in cognitive trajectories of diverse older adults

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Later birth year was associated with higher initial cognitive levels for Whites and Blacks, but not Hispanics. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-10-28

    Impacts of exercise intervention on various diseases in rats

    ✓ Peer-reviewed Prevention trials Journal of sport and health science

    Key finding: The collected articles were categorized into studies related to 6 systems or disease types: motor system (17 articles), metabolic system (110 articles), cardiocerebral vascular system (171 articles), nervous system (71 articles), urinary system (2 articles), and cancer (21 articles). +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-10-28

    [18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series

    ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications

    Key finding: Despite the presence of abundant tau aggregates in multiple regions in all CTE brains, only faint or no [18F]-AV-1451 binding signal could be detected by autoradiography. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2019-10-28

    Addressing the “Total Taxpayer” Problem to Translate Veterans Health Administration Innovations in Long-Term Supports

    ⚠ Report — not peer-reviewed Health systems and care delivery Public Policy & Aging Report

    Key finding: This includes adapting and disseminating care delivery innovations from one system to another, as well as measuring and sharing in the improved outcomes and reduced costs that might result. +4 more findings

    Scored 34 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  13. 2019-10-28

    Geographic Variation in Prevalence of Adult Obesity in China: Results From the 2013–2014 National Chronic Disease and Risk Factor Surveillance

    ✓ Peer-reviewed Risk factors Annals of Internal Medicine

    Key finding: Letters18 February 2020Geographic Variation in Prevalence of Adult Obesity in China: Results From the 2013–2014 National Chronic Disease and Risk Factor SurveillanceXiao Zhang, MD, PhD, Mei Zhang, MD, PhD, Zhenping Zhao, MD, Zhengjing Huang, MPH, Qian Deng, MD, PhD, Yichong Li, MD, PhD, An Pan, MD, +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-10-26

    Development of a dyadic sleep intervention for Alzheimer's disease patients and their caregivers

    ✓ Peer-reviewed Caregiving Disability and rehabilitation

    Key finding: Five out of six enrolled dyads completed the sessions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-10-25

    Genome-Wide Association Studies for Cerebrospinal Fluid Soluble TREM2 in Alzheimer's Disease

    ✓ Peer-reviewed Genetics Frontiers in aging neuroscience

    Key finding: We found CSF sTREM2 levels were elevated with the disease stages, but there was no significant difference between that of AD patients and normal participants. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-10-25

    Integrate GWAS, eQTL, and mQTL Data to Identify Alzheimer's Disease-Related Genes

    ✓ Peer-reviewed Genetics Frontiers in genetics

    Key finding: In this paper, expression quantitative trait locus (eQTL) studies and methylation quantitative trait locus (mQTL) studies are combined with GWAS to find the genes associated with Alzheimer disease in expression levels by pleiotropy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2019-10-25

    Lower CSF Amyloid-Beta1-42 Predicts a Higher Mortality Rate in Frontotemporal Dementia

    ✓ Peer-reviewed Tau biomarkers Diagnostics (Basel, Switzerland)

    Key finding: Patients who died during follow up had a significantly lower CSF amyloid-beta1-42 than those who did not. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2019-10-25

    Association between increased levels of amyloid-β oligomers in plasma and episodic memory loss in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: The elevated levels of OAβ in the plasma distinguished the AD and control groups and were associated with the severity of symptoms, especially memory performance, in patients with AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →