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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,001–11,025 of 27,380 studies, newest first · page 441 of 1096.

November 2020 20

  1. 2020-11-02

    Dynamic brain fluctuations outperform connectivity measures and mirror pathophysiological profiles across dementia subtypes: A multicenter study

    ✓ Peer-reviewed Digital health tools NeuroImage

    Key finding: Yet, traditional fMRI research on resting-state networks (RSNs) has favored static and average connectivity methods, which by overlooking the fluctuation dynamics triggered by neurodegeneration, have yielded inconsistent results. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-11-02

    Associations between physical frailty and dementia incidence: a prospective study from UK Biobank

    ✓ Peer-reviewed Prevention and risk The lancet. Healthy longevity

    Key finding: Of 502 535 participants in UK Biobank, 143 215 met the inclusion criteria and were included in our analyses. 68 500 (47·8%) of the participants were pre-frail and 5565 (3·9%) were frail. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-11-01

    Open Peer Commentary to “Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE Trials as reported by Biogen December 2019”

    ✓ Peer-reviewed Treatments Alzheimer s & Dementia

    Key finding: The results of the aducanumab studies have not been published in peer-reviewed form and both the analysis presented by Dr Knopman and collaborators and this perspective are based on data presented in 2019 at the Clinical Trials in AD (CTAD) meeting3; both discussions must be seen as tentative until full data are available. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-11-01

    Traffic-related Noise Exposure and Late-life Dementia and Cognitive Impairment in Mexican-Americans

    ✓ Peer-reviewed Risk factors Epidemiology (Cambridge, Mass.)

    Key finding: During the follow-up, we identified 159 incident dementia or CIND cases in total. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-11 month only

    New pharmacologic agents for insomnia and hypersomnia

    ✓ Peer-reviewed Risk factors Current opinion in pulmonary medicine

    Key finding: Insomnia and hypersomnia are conditions with multifactorial causes that can be difficult to treat.

    Full summary, score breakdown and related studies → Original source

  6. 2020-11-01

    PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records

    ✓ Peer-reviewed Digital health tools Journal of the American Medical Informatics Association : JAMIA

    Key finding: PheMap significantly streamlines the process of extracting research-quality phenotype information from EHRs, with comparable or better performance to current phenotyping approaches. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-11-01

    Unmet needs in Parkinson disease: Motor and non-motor

    ✓ Peer-reviewed End-of-life care Parkinsonism & related disorders

    Key finding: Compared to other neurodegenerative diseases, Parkinson's disease (PD) is distinctive in terms of marked symptomatic variability and prognosis, as well as for the wide variety of symptomatic treatment options.

    Full summary, score breakdown and related studies → Original source

  8. 2020-11-01

    Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019

    ✓ Peer-reviewed Treatments Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The sponsor claimed that subsets of participants receiving sufficiently high doses of aducanumab demonstrated benefits in both trials.

    Full summary, score breakdown and related studies → Original source

  9. 2020-11-01

    Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers The Journal of experimental medicine

    Key finding: We found p-tau-217 and p-tau-181 were highly specific for amyloid plaque pathology in the discovery cohort (n = 36, AUROC = 0.99 and 0.98 respectively).

    Full summary, score breakdown and related studies → Original source

  10. 2020-11-01

    Effectiveness of Combined Cognitive and Physical Interventions to Enhance Functioning in Older Adults With Mild Cognitive Impairment: A Systematic Review of Randomized Controlled Trials

    ✓ Peer-reviewed Prevention trials The Gerontologist

    Key finding: Intervention participants with MCI self-reported, or demonstrated, improved functioning across a range of cognitive (global cognitive function, executive function, processing speed, memory, attention, mood, emotion, motivation, brain cortex, orientation), and physical (gait, balance, mobility) outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2020-11-01

    Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

    ✓ Peer-reviewed Disease mechanisms JAMA neurology

    Key finding: Of 60 patients with PSP, 40 (66.7%) had RS (22 men [55.0%]; mean [SD] age, 71 [6] years; mean [SD] PSP rating scale score, 38 [15]; score range, 13-71) and 20 (33.3%) had PSP-non-RS (11 men [55.0%]; mean [SD] age, 71 [9] years; mean [SD] PSP rating scale score, 24 [11]; score range, 11-41). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2020-11-01

    Cognitive Assessment At Medicare’s Annual Wellness Visit In Fee-For-Service And Medicare Advantage Plans

    ✓ Peer-reviewed Health systems and care delivery Health Affairs

    Key finding: Overall, approximately one-half of beneficiaries surveyed reported having an annual wellness visit, and fewer than one-third reported having a structured cognitive assessment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2020-11-01

    Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

    ✓ Peer-reviewed Brain tissue and pathology The Journal of clinical investigation

    Key finding: Testing potential therapies in clinical trials is hampered by our inability to distinguish between patients with FTLD-TDP and FTLD-tau. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-11-01

    Long-Term Respiratory and Neurological Sequelae of COVID-19

    ✓ Peer-reviewed Brain tissue and pathology Medical science monitor : international medical journal of experimental and clinical research

    Key finding: Initially, the large number of infected people required the direction of global healthcare resources to provide supportive care for the acutely ill population in an attempt to reduce mortality. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-11-01

    Conference report: dementia research and care and its impact in Switzerland

    ✓ Peer-reviewed Drug development Swiss medical weekly

    Key finding: To study pathophysiological changes, as well as the underlying mechanism of fluid biomarker changes, excellent experimental approaches, including transgenic mouse models, are available. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-11-01

    Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

    ✓ Peer-reviewed TREM2 and immune genetics Human molecular genetics

    Key finding: We have investigated the role of TREM2 in primary microglial cultures from wild type mice by using siRNA to decrease Trem2 expression, and in parallel from knock-in mice heterozygous or homozygous for the Trem2 R47H AD risk variant. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-11-01

    Association of Delirium With Long-term Cognitive Decline: A Meta-analysis

    ✓ Peer-reviewed Risk factors JAMA neurology

    Key finding: Of 1583 articles, data subjected from the 24 studies (including 3562 patients who experienced delirium and 6987 controls who did not) were included in a random-effects meta-analysis for pooled effect estimates and random-effects meta-regressions to identify sources of study variance. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020-11-01

    A systematic literature review of automatic Alzheimer's disease detection from speech and language

    ✓ Peer-reviewed Digital health tools Journal of the American Medical Informatics Association : JAMIA

    Key finding: The systematic literature review supported the argument that language and speech could successfully be used to detect dementia automatically. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2020-11-01

    How Effective Are Dementia Caregiver Interventions? An Updated Comprehensive Meta-Analysis

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Interventions had, on average, a significant, small-to-moderate effect on the improvement of ability/knowledge, subjective well-being, burden, depression, and the caregiver's anxiety as well as symptoms of the care recipient. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2020-11-01

    Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: However, uncertainty remains regarding the optimal timepoint, combination, and an order in which these PET biomarkers should be used in diagnostic evaluations because conclusive evidence is missing. +4 more findings

    Full summary, score breakdown and related studies → Original source

October 2020 5

  1. 2020-10-31

    Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: Progressive tau accumulation may be more prominent in ε4 carriers, particularly in the medial and lateral temporal cortices.

    Full summary, score breakdown and related studies → Original source

  2. 2020-10-31

    Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)

    ✓ Peer-reviewed Biomarkers Environmental health and preventive medicine

    Key finding: The prospective cohort data from the JPSC-AD will provide valuable insights regarding the risk factors and etiology of dementia as well as for the development of predictive models and diagnostic markers for the future onset of dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2020-10-31

    Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Neurologia

    Key finding: We performed a retrospective analysis of the patients assessed at our memory unit for whom Alzheimer disease (AD) cerebrospinal fluid biomarker results were available. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-10-30

    Wine Intake in the Framework of a Mediterranean Diet and Chronic Non-Communicable Diseases: A Short Literature Review of the Last 5 Years

    ✓ Peer-reviewed Prevention trials Molecules (Basel, Switzerland)

    Key finding: Within the MedDiet, moderate wine consumption with meals is a positive item in the MedDiet score; however, recent studies have reported a dose-response association between alcohol consumption and higher risk of a large number of NCDs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2020-10-30

    microRNA-Based Biomarkers in Alzheimer's Disease (AD)

    ✓ Peer-reviewed Disease mechanisms Frontiers in neuroscience

    Key finding: Alterations in microRNA (miRNA) signaling have been implicated in the epigenetics and molecular genetics of all neurobiological processes associated with AD pathophysiology. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →