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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,001–10,025 of 27,380 studies, newest first · page 401 of 1096.

July 2021 25

  1. 2021-07-14

    The Effects of Multi-Domain Interventions on Cognition: A Systematic Review

    ✓ Peer-reviewed Prevention trials Western journal of nursing research

    Key finding: Future research is warranted to identify the optimal multi-domain intervention components that can induce clinically significant beneficial effects on cognition.

    Full summary, score breakdown and related studies → Original source

  2. 2021-07-14

    Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down syndrome

    ✓ Peer-reviewed Biomarkers Nature communications

    Key finding: Plasma p-tau181 concentration showed an area under the curve of 0.80 [95% CI 0.73-0.87] and 0.92 [95% CI 0.89-0.95] for the discrimination between asymptomatic individuals versus those in the prodromal and dementia groups, respectively. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2021-07-14

    Factors Associated With Emergency Department Visits by People With Dementia Near the End of Life: A Systematic Review

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: The review highlights characteristics that could help identify patients at risk of ED attendance near the end of life and potential service-related factors to reduce risks. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-07-13

    Association between plasma neurofilament light chain levels and cognitive function in patients with Parkinson's disease

    ✓ Peer-reviewed Biomarkers Journal of neuroimmunology

    Key finding: Our results shown that plasma NfL levels increased with an increase in cognitive impairment across the three groups of PD patients: PD with normal cognition (PD-NC), 17.9 ± 8.9 pg/ml; PD with mild cognitive impairment (PD-MCI),21.9 ± 10.3 pg/ml; and PD dementia (PDD), 35.7 ± 21.7 pg/ml. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-07-13

    Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model

    ✓ Peer-reviewed Biomarkers Theranostics

    Key finding: The data revealed that 5XFAD mice that received hMSC-EV treatment behaved significantly better in cognitive tests than saline treated 5XFAD mice, with no significant change between EV-treated 5XFAD mice and NT mice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-07-13

    Tau PET correlates with different Alzheimer's disease-related features compared to CSF and plasma p-tau biomarkers

    ✓ Peer-reviewed Mild cognitive impairment EMBO molecular medicine

    Key finding: PET, CSF and plasma biomarkers of tau pathology may be differentially associated with Alzheimer's disease (AD)-related demographic, cognitive, genetic and neuroimaging markers. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-07-13

    Machine Learning Algorithm Using Electronic Chart-Derived Data to Predict Delirium After Elderly Hip Fracture Surgeries: A Retrospective Case-Control Study

    ✓ Peer-reviewed Digital health tools Frontiers in surgery

    Key finding: About 245 patients were included and postoperative delirium affected 12.2% (30/245) of the patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-07-12

    Neighborhood racial/ethnic segregation and cognitive decline in older adults

    ✓ Peer-reviewed Disparities Social science & medicine (1982)

    Key finding: Among Latino participants, highly clustered Latino neighborhoods were associated with lower baseline scores in semantic memory, but slower declines in episodic memory; Latinos living in neighborhoods with a greater clustering of Black residents also had slower declines in episodic memory. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-07-12

    Autophagy and Tau Protein

    ✓ Peer-reviewed Drug development International journal of molecular sciences

    Key finding: This suggests that autophagy function is disturbed in AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2021-07-10

    Molecular Basis of Late-Life Depression

    ✓ Peer-reviewed Risk factors International journal of molecular sciences

    Key finding: Late-life depression (LLD), compared to depression at a young age, is more likely to have poor prognosis and high risk of progression to dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-07-10

    Activation of Glucagon-Like Peptide-1 Receptor Ameliorates Cognitive Decline in Type 2 Diabetes Mellitus Through a Metabolism-Independent Pathway

    ✓ Peer-reviewed Drug development Journal of the American Heart Association

    Key finding: We concluded that liraglutide improves cognitive decline in patients with type 2 diabetes mellitus. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-07-09

    Exposure to low-dose ambient fine particulate matter PM2.5 and Alzheimer’s disease, non-Alzheimer’s dementia, and Parkinson’s disease in North Carolina

    ✓ Peer-reviewed Risk factors PLoS ONE

    Key finding: Residents in the Study group of elevated air particulate matter (87 zip codes with PM2.5≥10μg/m3) were compared to the residents in the Control group with low levels of air particulate matter (81 zip codes with PM2.5≤7.61μg/m3), and were found to have higher age-adjusted rates of mortality and hospital admissions for AD, non-AD dementia, and PD, including a most pronounced increase in AD mortality (323/100,000 vs. 257/100,000, respectively). +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-07-09

    Dementia Syndrome of Depression: Diagnostic Challenges and Clinical Relevance

    ✓ Peer-reviewed Risk factors Focus (American Psychiatric Publishing)

    Key finding: Late-life depression is frequently associated with cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-07-08

    Hearing Loss and Dementia: A Meta-Analysis of Prospective Cohort Studies

    ✓ Peer-reviewed Risk factors Frontiers in aging neuroscience

    Key finding: Fourteen cohorts including 726,900 participants were analyzed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-07-08

    Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: In this study, we generated a genomic atlas of protein levels in three tissues relevant to neurological disorders (brain, cerebrospinal fluid and plasma) by profiling thousands of proteins from participants with and without Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-07-08

    Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease

    ✓ Peer-reviewed Genetics Nature genetics

    Key finding: Here, we present a multi-omic single-nucleus study of 191,890 nuclei in late-stage Alzheimer's disease (AD), accessible through our web portal, profiling chromatin accessibility and gene expression in the same biological samples and uncovering vast cellular heterogeneity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-07-08

    Developing the ATX(N) classification for use across the Alzheimer disease continuum

    ✓ Peer-reviewed Disease mechanisms Nature reviews. Neurology

    Key finding: The AT(N) system is a symptom-agnostic classification scheme that categorizes individuals using biomarkers that chart core AD pathophysiological features, namely the amyloid-β (Aβ) pathway (A), tau-mediated pathophysiology (T) and neurodegeneration (N). +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-07-07

    Blood biomarkers for the diagnosis of amnestic mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis

    ✓ Peer-reviewed Biomarkers Neuroscience and biobehavioral reviews

    Key finding: Finally, 150 articles were included, which demonstrated T-tau (average ratio: 1.25-1.62), P-tau 181 (1.36-2.16) and NfL (1.24-1.86) were increased, and AβPPr (0.65-0.88) were decreased from controls to amnestic mild cognitive impairment (aMCI) to AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2021-07-07

    BNT162b2 vaccine breakthrough: clinical characteristics of 152 fully vaccinated hospitalized COVID-19 patients in Israel

    ✓ Peer-reviewed Prevention and risk Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    Key finding: We found that severe COVID-19 infection, associated with a high mortality rate, might develop in a minority of fully vaccinated individuals with multiple co-morbidities. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-07-07

    Investigation of the effects of interventions made according to the Progressively Lowered Stress Threshold Model on the care outcomes of Alzheimer patients and their families: a randomized clinical trial

    ✓ Peer-reviewed Treatments Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

    Key finding: As a result of the PLST training, there was a decrease in the behavioural problems of Alzheimer's patients, along with a decrease in the care burden of the caregivers and an increase in their care satisfaction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-07-06

    Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading

    ✓ Peer-reviewed Inflammation and the immune system Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Our results reveal an essential role for microglial autophagy in regulating lipid homeostasis, neuroinflammation, and tau pathology.

    Full summary, score breakdown and related studies → Original source

  22. 2021-07-06

    Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain

    ✓ Peer-reviewed Inflammation and the immune system Journal of neuroinflammation

    Key finding: Administration of DSS induced colitis, impaired spatial and recognition memory, activated microglia, and increased A1-like astrocyte numbers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-07-05

    Plasma biomarker profiles and the correlation with cognitive function across the clinical spectrum of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Plasma p-tau181 had correlations with broader cognitive domains, suggesting its potential as a promising clinical-relevant blood-based biomarker. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2021-07-04

    Exploring Differential Perceptions and Barriers to Advance Care Planning in Dementia among Asian Patient-Caregiver Dyads-A Mixed-Methods Study

    ✓ Peer-reviewed End-of-life care International journal of environmental research and public health

    Key finding: Post-ACP counseling, caregivers were significantly more likely to acknowledge barriers to ACP discussions than patients (57.9% versus 10.5%, p = 0.005). +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2021-07-03

    The Relationship Between the Gut Microbiome and Neurodegenerative Diseases

    ✓ Peer-reviewed Disease mechanisms Neuroscience bulletin

    Key finding: Many recent studies have shown that the gut microbiome plays important roles in human physiology and pathology. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →