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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,226–11,250 of 27,380 studies, newest first · page 450 of 1096.

September 2020 25

  1. 2020-09-04

    Cost-effectiveness of the Namaste care family program for nursing home residents with advanced dementia in comparison with usual care: a cluster-randomized controlled trial

    ✓ Peer-reviewed Treatments BMC health services research

    Key finding: The Namaste Care Family program is dominant over usual care and, thus, cost-effective, although statistical uncertainty was considerable. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-09-04

    Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain

    ✓ Peer-reviewed Genetics Nature communications

    Key finding: The molecular signatures of cells in the brain have been revealed in unprecedented detail, yet the ageing-associated genome-wide expression changes that may contribute to neurovascular dysfunction in neurodegenerative diseases remain elusive. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-09-03

    Associations Between Multidomain Lifestyle Interventions and Intrinsic Capacity Domains During Aging: A Narrative Review

    ✓ Peer-reviewed Prevention trials JAR life

    Key finding: Multidomain interventions were associated with improvements on locomotion (as measured by performance-based tests of lower-limb function) and vitality (as measured by handgrip strength); benefits on cognitive function were also found, in particular among populations at increased risk of dementia and when operationalizing strong multidomain interventions (eg, using regular exercise training instead of physical activity advices). +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-09-03

    A Multi-Domain Intervention Protocol for the Potential Reversal of Cognitive Frailty: "WE-RISE" Randomized Controlled Trial

    ✓ Peer-reviewed Prevention trials Frontiers in public health

    Key finding: Ambulating, community dwelling older adults aged 60 years and above with cognitive frailty are randomized into two groups; (1) intervention group: which receives an instructor based "WE-RISE" intervention for the first 3 months, and then a home-based "WE-RISE at Home" intervention for the following 3 months; (2) control group: usual care with no modifications to their daily routine. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-09-02

    [Dementia prevention and primary care: Estimation of the target population]

    ✓ Peer-reviewed Risk factors Fortschritte der Neurologie-Psychiatrie

    Key finding: In a sample of 2,398,405 patients receiving primary care, the target population relevant for dementia prevention measures in 2018 consisted of 191,883 patients with hypertension, 23,308 with obesity, 5,059 with hearing loss, 120,200 with diabetes and 43,233 with depression. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-09-02

    Association of genetic risk for Alzheimer disease and hearing impairment

    ✓ Peer-reviewed Risk factors Neurology

    Key finding: Poor speech-in-noise hearing (>-5.5-dB speech reception threshold; prevalence 14%) was associated with lower cognitive scores (ß = -1.28; 95% confidence interval [CI] -1.54 to -1.03). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-09-02

    The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease

    ✓ Peer-reviewed Brain tissue and pathology Nature

    Key finding: Here we identify interferon-induced transmembrane protein 3 (IFITM3) as a γ-secretase modulatory protein, and establish a mechanism by which inflammation affects the generation of amyloid-β. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-09-01

    Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: Another proposed neuropathological feature related to TDP-43 proteinopathy in aged individuals is 'Alpha' versus 'Beta' in amygdala. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020-09 month only

    Dietary Interventions to Prevent or Delay Alzheimer's Disease: What the Evidence Shows

    ✓ Peer-reviewed Prevention and risk Current nutrition reports

    Key finding: A variety of potentially modifiable risk factors have been investigated in an attempt to delay/prevent Alzheimer's disease (AD).

    Full summary, score breakdown and related studies → Original source

  10. 2020-09 month only

    Considerations for integrative multi-omic approaches to explore Alzheimer's disease mechanisms

    ✓ Peer-reviewed Genetics Brain pathology (Zurich, Switzerland)

    Key finding: In a growing number of cases, the same samples were profiled with multiple different approaches, yielding genetic, transcriptomic, epigenomic and proteomic data. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-09-01

    ApoE Lipidation as a Therapeutic Target in Alzheimer's Disease

    ✓ Peer-reviewed Genetics International journal of molecular sciences

    Key finding: To perform its normal functions, apoE must be secreted and properly lipidated, a process influenced by the structural differences associated with apoE isoforms. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2020-09-01

    Inflammatory effects of particulate matter air pollution

    ✓ Peer-reviewed Risk factors Environmental science and pollution research international

    Key finding: Inflammation is a common hallmark in the pathogenesis of many of these diseases associated with exposure to a variety of air pollutants, including PM.

    Full summary, score breakdown and related studies → Original source

  13. 2020-09-01

    Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans

    ✓ Peer-reviewed Genetics Cell reports

    Key finding: Our comparison of microglia from single cells and single nuclei of four human subjects reveals that, although most genes show similar relative abundances in cells and nuclei, a small population of genes (∼1%) is depleted in nuclei compared to whole cells. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2020-09-01

    Phosphorylated tau interactome in the human Alzheimer's disease brain

    ✓ Peer-reviewed Genetics Brain : a journal of neurology

    Key finding: Twenty-nine of these proteins have been previously associated with phosphorylated tau, therefore validating our proteomic approach. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-09-01

    Are We There Yet? Immersive Virtual Reality to Improve Cognitive Function in Dementia and Mild Cognitive Impairment

    ✓ Peer-reviewed Prevention trials The Gerontologist

    Key finding: Our search identified a total of 2,824 citations, following screening for duplicates and application of inclusion and exclusion criteria, five studies were included for analysis.

    Full summary, score breakdown and related studies → Original source

  16. 2020-09-01

    Dietary Factors and Neurodegenerative Disorders: An Umbrella Review of Meta-Analyses of Prospective Studies

    ✓ Peer-reviewed Prevention trials Advances in nutrition (Bethesda, Md.)

    Key finding: Diet has been hypothesized to be associated with neurodegenerative disorders. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-09-01

    Die Entwicklung der geschätzten Anzahl an Demenz erkrankter Menschen auf Kreisebene in Deutschland für 2030

    ✓ Peer-reviewed Risk factors Psychiatrische Praxis

    Key finding: In 2030 it is expected that approx. 2.170.000 PwD above age 65 are living in Germany. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020-09-01

    Activation of 574 new Alzheimer’s special care unit beds in the Metropolitan City of Milan

    ✓ Peer-reviewed Health systems and care delivery European Journal of Public Health

    Key finding: Preliminary results indicate 29 residential care facilities applied for evaluation in 2019.

    Full summary, score breakdown and related studies → Original source

  19. 2020-09-01

    Inflammation, apoptosis and autophagy as critical players in vascular dementia

    ✓ Peer-reviewed Inflammation and the immune system European review for medical and pharmacological sciences

    Key finding: Hence, vascular damage is a critical cause of neuronal loss and synaptic disintegration. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020-09-01

    18F-MK-6240 PET for early and late detection of neurofibrillary tangles

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: It is expected that Braak staging using brain imaging can stratify living individuals according to their individual patterns of tau deposition, which may prove crucial for clinical trials and practice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2020-09-01

    Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: Cross-sectional data, including CSF analytes, molecular imaging of cerebral fibrillar β-amyloid (Aβ) with PET using the [ 11 C] benzothiazole tracer Pittsburgh compound B (PiB), MRI-based brain structures, and clinical/cognitive outcomes harmonized from 8 studies, collectively involving 3,284 cognitively normal individuals 18 to 101 years of age, were analyzed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2020-09-01

    Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of clinical investigation

    Key finding: Beyond tau and Aβ, evidence suggests that microglia play an important role in AD pathogenesis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020-09-01

    Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of experimental medicine

    Key finding: The R47H variant of human TREM2 impairs ligand binding and increases Alzheimer's disease (AD) risk. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-09-01

    Derivatives of diisopropyl phenoxyphosphate with controlled reactivity for enhancement of Acetylcholine (ACh) neurotransmitter

    ✓ Peer-reviewed Down syndrome and Alzheimer's Pakistan journal of pharmaceutical sciences

    Key finding: This led to structural design of derivatives of diisopropyl phenoxyphosphate with controlled reactivity stemming from para substituted phenoxide leaving group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2020-09-01

    Differential Associations of Apolipoprotein E ε4 Genotype With Attentional Abilities Across the Life Span of Individuals With Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's JAMA network open

    Key finding: The ε4 allele of the apolipoprotein E gene (APOE ε4) is associated with an additional risk for AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →