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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,626–10,650 of 27,380 studies, newest first · page 426 of 1096.

January 2021 25

  1. 2021-01-25

    Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Our study highlights factors associated with the development of CMHs in individuals with DIAD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-01-25

    The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: P-tau181 detected AD at MCI and dementia stages and was strongly associated with cognitive decline and gray matter loss. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-01-25

    The Immunopathogenesis of Alzheimer's Disease Is Related to the Composition of Gut Microbiota

    ✓ Peer-reviewed Prevention trials Nutrients

    Key finding: In patients with Alzheimer's disease (AD) significant alterations of the gut microbiota have been demonstrated. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2021-01-25

    Screening of Alzheimer's disease by facial complexion using artificial intelligence

    ✓ Peer-reviewed Digital health tools Aging

    Key finding: Despite the increasing incidence and high morbidity associated with dementia, a simple, non-invasive, and inexpensive method of screening for dementia is yet to be discovered. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-01-25

    In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model

    ✓ Peer-reviewed Biomarkers Journal of neuroscience methods

    Key finding: Congo Red (CR) has been used for its binding affinity to amyloid fibrils for the better part of a century. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-01-23

    Head-to-head comparison of amplified plasmonic exosome Aβ42 platform and single-molecule array immunoassay in a memory clinic cohort

    ✓ Peer-reviewed Biomarkers European journal of neurology

    Key finding: Compared to Simoa biomarkers, APEX-Aβ42 showed significantly higher correlations with amyloid PET retention values and excellent diagnostic performance (sensitivity 100%, specificity 93.3%, area under the curve 0.995). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-01-22

    Decoding Mast Cell-Microglia Communication in Neurodegenerative Diseases

    ✓ Peer-reviewed Inflammation and the immune system International journal of molecular sciences

    Key finding: Mast cells act as 'first responders' to a pathogenic stimuli and respond by degranulation and releasing these mediators into the extracellular milieu. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-01-22

    α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Misfolded protein aggregates in the form of Lewy bodies, comprised mainly of α-synuclein (αSyn), are associated with disease progression, and have also been linked to other neurodegenerative diseases, including Lewy body dementia, Alzheimer's disease, and frontotemporal dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-01-22

    The effect of direct cognitive assessment in the Medicare annual wellness visit on dementia diagnosis rates

    ✓ Peer-reviewed Risk factors Health Services Research

    Key finding: Annual Wellness Visit utilization was associated with an increased probability of new dementia diagnosis with effects varying by racial group (categorized as white, black, Hispanic/Latino, or Asian based on Social Security Administration data). +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-01-21

    Characteristics of Advance Care Planning Interventions Across Dementia Stages: A Systematic Review

    ✓ Peer-reviewed End-of-life care Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing

    Key finding: Three ACP interventions focused on mild dementia and seven on advanced dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-01-21

    Bilingualism's Effects on Resting-State Functional Connectivity in Mild Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging Brain connectivity

    Key finding: We found no significant differences between the groups in age, sex, education, or cognitive level, but bilinguals showed higher FC than monolinguals between the posterior part of the superior temporal gyrus and the precuneus, positively correlated with Mini-Mental State Examination scores, and higher fALFF in the thalamus bilaterally. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2021-01-21

    Modeling autosomal dominant Alzheimer's disease with machine learning

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The Relief algorithm identified the caudate, cingulate, and precuneus as the strongest predictors among all modalities. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-01-21

    Red-to-blue paper-based colorimetric sensor integrated with smartphone for point-of-use analysis of cerebral AChE upon Cd2+ exposure

    ✓ Peer-reviewed Cognitive tests and assessment Nanoscale

    Key finding: Herein, combined with a pervasive smartphone installed with a color recognition app, dual-responsive CDs@Eu/GMP ICPs were designed as a red-to-blue paper-based colorimetric sensor for the point-of-use analysis of cerebral acetylcholinesterase (AChE) upon Cd2+ exposure. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-01-21

    The economic cost of delirium: A systematic review and quality assessment

    ✓ Peer-reviewed Clinical safety Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This review found significant variation among the cost estimates and methodological quality. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2021-01-21

    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

    ✓ Peer-reviewed Clinical safety Cell

    Key finding: We developed a platform to interrogate the chromatin accessibility landscape and transcriptional program within neurons during degeneration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-01-21

    Suggested Patient Selection Criteria for Initial Clinical Trials of Pig Kidney Xenotransplantation in the United States

    ✓ Peer-reviewed Risk factors Transplantation

    Key finding: Chronic dialysis is associated with relatively high mortality and increased comorbidities that may render the patient unsuitable for renal transplantation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-01-21

    Deep Learning-Based Classification and Voxel-Based Visualization of Frontotemporal Dementia and Alzheimer's Disease

    ✓ Peer-reviewed Long-term cohort studies Frontiers in neuroscience

    Key finding: Previous studies suggest that the deep learning (DL) techniques have the potential to solve the differential diagnosis problem of FTD, AD and normal controls (NCs), but its performance is still unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-01-20

    An Integrated Multi-omics Approach Identifies Therapeutic Potential for ATP6V1A in Late Onset Alzheimer's Disease

    ✓ Peer-reviewed Drug development Neuron

    Key finding: In this issue of Neuron, Wang et al. employ an impressive multi-omics approach, including gene co-expression network analyses and drug repositioning, to normalize disease-disrupted gene modules and identify a therapeutically relevant driver of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  19. 2021-01-20

    Restoring metabolism of myeloid cells reverses cognitive decline in ageing

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: The ageing brain is also vulnerable to inflammation, as demonstrated by the high prevalence of age-associated cognitive decline and Alzheimer's disease 4-6 . +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-01-20

    Past, Present, and Future of Non-invasive Brain Stimulation Approaches to Treat Cognitive Impairment in Neurodegenerative Diseases: Time for a Comprehensive Critical Review

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: We here review evidence gathered for nearly a decade on non-invasive brain stimulation (NIBS), a less known therapeutic strategy aiming to limit cognitive decline associated with neurodegenerative conditions.

    Full summary, score breakdown and related studies → Original source

  21. 2021-01-20

    Long-term exposure to ambient air pollution and risk of dementia: Results of the prospective Three-City Study

    ✓ Peer-reviewed Disparities Environment international

    Key finding: In this large cohort of older adults, long-term PM2.5 exposure was associated with increased dementia incidence. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-01-19

    Psychosis Management in Lewy Body Dementia: A Comprehensive Clinical Approach

    ✓ Peer-reviewed End-of-life care Journal of geriatric psychiatry and neurology

    Key finding: Lewy body dementia (LBD) is asynucleinopathy that results in clinical manifestation of motor and neuropsychiatric symptoms. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-01-19

    rs1990622 variant associates with Alzheimer's disease and regulates TMEM106B expression in human brain tissues

    ✓ Peer-reviewed Long-term cohort studies BMC medicine

    Key finding: It has been well established that the TMEM106B gene rs1990622 variant was a frontotemporal dementia (FTD) risk factor. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2021-01-19

    Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway

    ✓ Peer-reviewed Biomarkers Autophagy

    Key finding: Autophagy induction by crocetin significantly increased Aβ clearance in N9 cells. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2021-01-19

    Serum markers glial fibrillary acidic protein and neurofilament light for prognosis and monitoring in cognitively normal older people: a prospective memory clinic-based cohort study

    ✓ Peer-reviewed Biomarkers The lancet. Healthy longevity

    Key finding: Both high baseline GFAP (hazard ratio 3·6, 95% CI 2·2-5·7; p 42/40 , both GFAP (2·6, 1·4-5·0; p=0·0026) and amyloid β 42/40 (2·1, 1·2-3·6; p=0·0091) were independently associated with incident dementia whereas NfL was not (1·4, 0·8-2·5; p=0·28). +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →