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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,126–11,150 of 27,380 studies, newest first · page 446 of 1096.

October 2020 16

  1. 2020-10-01

    Selected Articles from This Issue

    ✓ Peer-reviewed Risk factors Cancer Epidemiology Biomarkers & Prevention

    Key finding: Overall cancer mortality rates were 12.3% higher in persistent poverty counties versus all others, and 9.6% higher in persistent versus current poverty counties, with even greater disparities observed for specific cancer sites. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-10-01

    Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases

    ✓ Peer-reviewed Inflammation and the immune system Science (New York, N.Y.)

    Key finding: To date, however, no early biomarkers or effective therapies exist. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-10-01

    Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants

    ✓ Peer-reviewed Long-term cohort studies JAMA network open

    Key finding: Several clinical trials are planned for familial forms of frontotemporal lobar degeneration (f-FTLD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-10-01

    Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity

    ✓ Peer-reviewed Long-term cohort studies Brain imaging and behavior

    Key finding: The deleterious effects of this genotype on brain structure may increase in magnitude into older age. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-10-01

    Parkinson's disease determinants, prediction and gene-environment interactions in the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Journal of neurology, neurosurgery, and psychiatry

    Key finding: We identified individuals with an incident diagnosis of PD (n=1276) and controls (n=500 406) in UK Biobank. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-10-01

    Glymphatic failure as a final common pathway to dementia

    ✓ Peer-reviewed Risk factors Science (New York, N.Y.)

    Key finding: Sleep is evolutionarily conserved across all species, and impaired sleep is a common trait of the diseased brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-10-01

    Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort

    ✓ Peer-reviewed How common it is The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: There are specific high-risk preexisting comorbidities for COVID-19 hospitalization and related deaths in community-based older men and women. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-10-01

    Effect of Aspirin vs Placebo on the Prevention of Depression in Older People: A Randomized Clinical Trial

    ✓ Peer-reviewed Disparities JAMA psychiatry

    Key finding: Low-dose aspirin did not prevent depression in this large-scale study of otherwise healthy older adults. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020-10-01

    Assessment of Rural-Urban Differences in Health Care Use and Survival Among Medicare Beneficiaries With Alzheimer Disease and Related Dementia

    ✓ Peer-reviewed Disparities JAMA network open

    Key finding: Study results suggest that, after diagnosis, rural Medicare beneficiaries with ADRD spend more time in nursing homes and less time in the community, receive less home health care, and have shorter survival than their urban counterparts. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-10-01

    Association of Receipt of Palliative Care Interventions With Health Care Use, Quality of Life, and Symptom Burden Among Adults With Chronic Noncancer Illness: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Caregiving JAMA

    Key finding: In this systematic review and meta-analysis of randomized clinical trials of patients with primarily noncancer illness, palliative care, compared with usual care, was statistically significantly associated with less acute health care use and modestly lower symptom burden, but there was no significant difference in quality of life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-10-01

    Translating genetic risk of Alzheimer's disease into mechanistic insight and drug targets

    ✓ Peer-reviewed Prevention and risk Science (New York, N.Y.)

    Key finding: However, the definition of AD has been confounded with dementia in many studies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-10-01

    Medical Care of Adults With Down Syndrome: A Clinical Guideline

    ✓ Peer-reviewed Prevention and risk JAMA

    Key finding: From 11 295 literature citations associated with 10 PICO questions, 20 relevant studies were identified.

    Full summary, score breakdown and related studies → Original source

  13. 2020-10-01

    Physical Activity and Exercise in Mild Cognitive Impairment and Dementia: An Umbrella Review of Intervention and Observational Studies

    ✓ Peer-reviewed Prevention and risk Journal of the American Medical Directors Association

    Key finding: Supported by very low-to-moderate certainty of evidence, physical activity/exercise has a positive effect on several cognitive and noncognitive outcomes in people with MCI and dementia, but RCTs, with low risk of bias/confounding, are still needed to confirm these relationships. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2020-10-01

    Benefit-Finding Intervention Delivered Individually to Alzheimer Family Caregivers: Longer-Term Outcomes of a Randomized Double-Blind Controlled Trial

    ✓ Peer-reviewed Treatments The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Benefit-finding is an efficacious intervention for depressive symptoms in Alzheimer caregivers, with strong effects in the medium-term post-intervention and possible moderate effects in the longer-term post-intervention. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2020-10-01

    Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: However, the clinical presentation, associated factors, frequency in community-based cohorts, genetic characteristics, and cognitive trajectories associated with the quadruple misfolded proteins phenotype are not well understood. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-10-01

    Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: The largest cohort, the Anti-Amyloid Treatment in Asymptomatic Alzheimer Disease Study (n = 3154), was the PET screening cohort used for a secondary prevention trial designed to slow cognitive decline associated with brain amyloidosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

September 2020 9

  1. 2020-09-30

    Intervention Fidelity of a Volunteer-Led Montessori-Based Intervention in a Canadian Long-Term Care Home

    ✓ Peer-reviewed Health systems and care delivery Canadian journal on aging = La revue canadienne du vieillissement

    Key finding: We found good evidence that volunteers attended scheduled visits, made use of pre-designed activities, and attended to training recommendations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2020-09-30

    Neurodegenerative hospital admissions and long-term exposure to ambient fine particle air pollution

    ✓ Peer-reviewed Risk factors Annals of epidemiology

    Key finding: Increases in ambient PM2.5 concentrations were not consistently associated with increased hospital admissions rates. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-09-30

    Practical nursing recommendations for palliative care for people with dementia living in long-term care facilities during the COVID-19 pandemic: A rapid scoping review

    ✓ Peer-reviewed End-of-life care International journal of nursing studies

    Key finding: We found no papers that informed the 'cultural aspects of care' domain. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2020-09-30

    Tau Protein and Its Role in Blood-Brain Barrier Dysfunction

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in molecular neuroscience

    Key finding: Neuropathology of tauopathies is defined as intracellular accumulation of neurofibrillary tangles (NFTs) consisting of aggregated hyper- and abnormal phosphorylation of tau protein and neuroinflammation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-09-30

    Astaxanthin Suppresses PM2.5-Induced Neuroinflammation by Regulating Akt Phosphorylation in BV-2 Microglial Cells

    ✓ Peer-reviewed TREM2 and immune genetics International journal of molecular sciences

    Key finding: Recent studies suggest that fine particulate matter of less than 2.5 (PM2.5), common in air pollution, can reach the brain, potentially resulting in the development and acceleration of various neurological disorders including Alzheimer's disease, Parkinson's disease, and other forms of dementia, but the underlying pathological mechanisms are not clear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-09-29

    Developments in the Market for Assisted Living: Residential Care Availability in 2017

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association

    Key finding: In comparison to counties with the lowest AL penetration, high-penetration counties had higher high school and college education attainment (mean 25.3% vs 18.5%) and median annual income ($56,000 vs $46,800), and lower poverty (12.8% vs 17.3%) and unemployment rates (3.9% vs 5.1%). +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-09-29

    Development and evaluation of an automated quantification tool for amyloid PET images

    ✓ Peer-reviewed Brain scans and imaging EJNMMI physics

    Key finding: Compared with manual step-by-step processing, our developed automated quantification tool reduced processing time by 85%. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-09-29

    Visual interpretation of [18F]Florbetaben PET supported by deep learning-based estimation of amyloid burden

    ✓ Peer-reviewed Brain scans and imaging European journal of nuclear medicine and molecular imaging

    Key finding: Inter-reader agreements for the visual reading based on a 3-point scale (BAPL score) calculated by Fleiss kappa coefficients were 0.46 and 0.76 for the visual reading without and with the deep learning system, respectively. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020-09-29

    COVID-19 Artificial Intelligence Diagnosis Using Only Cough Recordings

    ✓ Peer-reviewed Digital health tools IEEE open journal of engineering in medicine and biology

    Key finding: When validated with subjects diagnosed using an official test, the model achieves COVID-19 sensitivity of 98.5% with a specificity of 94.2% (AUC: 0.97). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →