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Selected Articles from This Issue
Cancer Epidemiology Biomarkers & Prevention, 2020-10-01
Topic: Risk, prevention and care in population studies
Overall cancer mortality rates were 12.3% higher in persistent poverty counties versus all others, and 9.6% higher in persistent versus current poverty counties, with even greater disparities observed for specific cancer sites. Persistent poverty counties have exceptionally high cancer mortality, and targeted research, policy, and intervention efforts are needed to reduce these geographic disparities in cancer.Many studies have shown that patients with Alzheimer disease are at decreased risk of cancer, but this inverse relation is likely to be biased by surveillance and survival bias. They showed that higher levels of plasma amyloid-β were associated with a higher risk of cancer, suggesting a potential biological link between Alzheimer disease and cancer. In three prospective cohorts including eight types of cancer, the total number of SEMs was associated with increased risk of breast, lung, and mature B-cell cancers in pre-diagnostic blood samples. Low and high serum calcium resulted in increased risk, whereas high serum 25(OH)D was a protective factor.
Key findings
- Overall cancer mortality rates were 12.3% higher in persistent poverty counties versus all others, and 9.6% higher in persistent versus current poverty counties, with even greater disparities observed for specific cancer sites.
- Persistent poverty counties have exceptionally high cancer mortality, and targeted research, policy, and intervention efforts are needed to reduce these geographic disparities in cancer.Many studies have shown that patients with Alzheimer disease are at decreased risk of cancer, but this inverse relation is likely to be biased by surveillance and survival bias.
- They showed that higher levels of plasma amyloid-β were associated with a higher risk of cancer, suggesting a potential biological link between Alzheimer disease and cancer.
- In three prospective cohorts including eight types of cancer, the total number of SEMs was associated with increased risk of breast, lung, and mature B-cell cancers in pre-diagnostic blood samples.
- Low and high serum calcium resulted in increased risk, whereas high serum 25(OH)D was a protective factor.
Why it matters
This summary highlights a study finding that higher levels of plasma amyloid-beta were linked to higher cancer risk, suggesting a possible biological link between Alzheimer's disease and cancer. It does not test any treatment, cure, or prevention for Alzheimer's disease.
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Study details
- Effect size12.3%; 9.6%
- Evidence strengthLow
How this study scored 27/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, studied in people and randomised / blinded because the record does not state it. We have no data on senior author's track record and institution's track record, so those were left out: it earned 25 of the 93 points we could judge it on, which is 27 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Cancer Epidemiology Biomarkers & Prevention) |
| Journal's citation record | 2 / 4 | Cancer Epidemiology Biomarkers & Prevention: journal h-index 210 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2020 — within 10 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 8 year(s) since 2020 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 0 institution(s) in 0 countries — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 25 / 93 | Scored on 18 of 20 parts. We have no data for the rest, so they are left out: 25 of the 93 points we could judge it on is 27 out of 100. |
| Total | 27 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. This record has no authors, so the citation leaves them out. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Selected Articles from This Issue. (2020). Cancer Epidemiology Biomarkers & Prevention. https://doi.org/10.1158/1055-9965.1841.29.10
Vancouver
Selected Articles from This Issue. Cancer Epidemiology Biomarkers & Prevention. 2020. doi:10.1158/1055-9965.1841.29.10.
BibTeX
@article{study2020-e9489aa9,
title = {{Selected Articles from This Issue}},
journal = {Cancer Epidemiology Biomarkers \& Prevention},
year = {2020},
doi = {10.1158/1055-9965.1841.29.10},
url = {https://doi.org/10.1158/1055-9965.1841.29.10}
}