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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,101–11,125 of 27,380 studies, newest first · page 445 of 1096.

October 2020 25

  1. 2020-10-08

    Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: The Apolipoprotein E ε4 allele (i.e. ApoE4) is the strongest genetic risk factor for sporadic Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-10-08

    Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1-42

    ✓ Peer-reviewed TREM2 and immune genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Triggering receptor expressed on myeloid cells-2 (TREM2) is an immune receptor expressed on microglia that also can become soluble (sTREM2). +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-10-08

    A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response

    ✓ Peer-reviewed TREM2 and immune genetics Nature communications

    Key finding: Most cancer patients do not respond to ICT and the availability of the predictive biomarkers is limited. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-10-08

    Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Vascular contributions to cognitive impairment and dementia (VCID) are characterized by the aging neurovascular unit being confronted with and failing to cope with biological insults due to systemic and cerebral vascular disease, proteinopathy including Alzheimer's biology, metabolic disease, or immune response, resulting in cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-10-07

    Hydroxytyrosol improves mitochondrial energetics of a cellular model of Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Nutritional neuroscience

    Key finding: Adherence to a Mediterranean diet is associated with lower incidence of cognitive decline and AD and extra virgin olive oil's (poly)phenols such as oleuropein and hydroxytyrosol (HT) are being actively studied in this respect. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-10-07

    Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica communications

    Key finding: GPNMB levels were significantly increased in the cerebrospinal fluid of FTD-GRN patients, but not in MAPT or C9orf72 carriers, suggesting GPNMB could be a biomarker specific to FTD-GRN to monitor disease onset, progression, and drug response. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2020-10-06

    Brain Amyloid Burden and Resting-State Functional Connectivity in Late Middle-Aged Hispanics

    ✓ Peer-reviewed Brain scans and imaging Frontiers in neurology

    Key finding: We found no significant linear or non-linear associations between Aβ, measured either continuously or categorically, with rsFC in the examined networks.

    Full summary, score breakdown and related studies → Original source

  8. 2020-10-06

    Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease

    ✓ Peer-reviewed Treatments Neuropharmacology

    Key finding: Overall, the efficacy of the three ChE-Is available in the market is similar and the benefit of administration of these compounds is mild and may not be clinically significant.

    Full summary, score breakdown and related studies → Original source

  9. 2020-10-06

    Associations of quantitative susceptibility mapping with Alzheimer's disease clinical and imaging markers

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: Altered iron metabolism has been hypothesized to be associated with Alzheimer's disease pathology, and prior work has shown associations between iron load and beta amyloid plaques. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-10-06

    Predicting the progression of mild cognitive impairment using machine learning: A systematic, quantitative and critical review

    ✓ Peer-reviewed Digital health tools Medical image analysis

    Key finding: We found that using cognitive, fluorodeoxyglucose-positron emission tomography or potentially electroencephalography and magnetoencephalography variables significantly improved predictive performance compared to not including them, whereas including other modalities, in particular T1 magnetic resonance imaging, did not show a significant effect.

    Full summary, score breakdown and related studies → Original source

  11. 2020-10-05

    Genetic Risk of Alzheimer's Disease and Sleep Duration in Non-Demented Elders

    ✓ Peer-reviewed Long-term cohort studies Annals of neurology

    Key finding: We studied whether genetic liability for AD predicts sleep duration using a genetic risk score (GRS) for AD (AD-GRS), in 406,536 UK Biobank participants with European ancestry and without dementia at enrollment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-10-03

    PM2.5 and hospital admissions among Medicare enrollees with chronic debilitating brain disorders

    ✓ Peer-reviewed Risk factors The Science of the total environment

    Key finding: We observed significant increases in all-cause hospital admissions (2.53% in PD and 2.49% in AD/dementia) attributable to high PM2.5 exposure. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2020-10-02

    Associations between gut microbiota and Alzheimer's disease, major depressive disorder, and schizophrenia

    ✓ Peer-reviewed Genetics Journal of neuroinflammation

    Key finding: These data for the first time provide evidence of potential causal links between gut microbiome and AD, MDD, and SCZ. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-10-02

    Cerebrospinal fluid A beta 1-40 peptides increase in Alzheimer's disease and are highly correlated with phospho-tau in control individuals

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: These results indicate that an increase in the baseline level of amyloid peptides, which are associated with an increase in p-tau (181), may be a biological characteristic and possibly a risk factor for AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-10-02

    Shared decision-making in advance care planning for persons with dementia in nursing homes: a cross-sectional study

    ✓ Peer-reviewed End-of-life care BMC geriatrics

    Key finding: At ward level, professionals and residents rated the average achieved level of shared decision-making 71.53/100 (σ = 16.09) and 81.11/100 (σ = 19.18) respectively. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2020-10-02

    Retinal Degeneration and Alzheimer's Disease: An Evolving Link

    ✓ Peer-reviewed Inflammation and the immune system International journal of molecular sciences

    Key finding: Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the retina and a significant cause of irreversible blindness in developed countries. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2020-10-02

    Glymphatic failure as a final common pathway to dementia

    ✓ Peer-reviewed Laboratory science Science

    Key finding: Glymphatic clearance is primarily active during sleep and declines with age +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020-10-01

    Neurological disorders vis-à-vis climate change

    ✓ Peer-reviewed Risk factors Early human development

    Key finding: People exposed to air pollutants have a higher risk of developing dementia and AD, but not PD.

    Full summary, score breakdown and related studies → Original source

  19. 2020-10 month only

    Does bilingualism protect against dementia? A meta-analysis

    ✓ Peer-reviewed Risk factors Psychonomic bulletin & review

    Key finding: Evidence suggests that bilingualism may contribute to neuroplasticity and cognitive reserve, allowing individuals to resist cognitive decline associated with Alzheimer's disease progression, although the idea remains controversial. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020-10-01

    Digitization of neuropsychological diagnostics: a pilot study to compare three paper-based and digitized cognitive assessments

    ✓ Peer-reviewed Cognitive tests and assessment Aging clinical and experimental research

    Key finding: Between the two versions (paper-based vs. digital) statistically significant correlations were found in all tests, e.g., TMT-A r(48) = 0.63, p < 0.01; TMT-B rs(48) = 0.77, p < 0.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2020-10-01

    Unilateral Cochlear Implants for Severe, Profound, or Moderate Sloping to Profound Bilateral Sensorineural Hearing Loss: A Systematic Review and Consensus Statements

    ✓ Peer-reviewed Risk factors JAMA otolaryngology-- head & neck surgery

    Key finding: These 20 consensus statements on the use of unilateral cochlear implantation in adults with SNHL were relevant to the following 7 key areas of interest: level of awareness of cochlear implantation (1 consensus statement); best practice clinical pathway from diagnosis to surgery (3 consensus statements); best practice guidelines for surgery (2 consensus statements); clinical effectiveness of cochlear implantation (4 consensus statements); factors associated with postimplantation outcomes (4 consensus statements); association between hearing loss and depression, cognition, and dementia (5 consensus statements); and cost implications of cochlear implantation (1 consensus statement). +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2020-10-01

    A systematic review of physical activity and quality of life and well-being

    ✓ Peer-reviewed Prevention trials Translational behavioral medicine

    Key finding: Strong evidence (predominantly from randomized controlled trials [RCTs]) demonstrated that, for adults aged 18-65 years and older adults (primarily 65 years and older), PA improves QoL and well-being when compared with minimal or no-treatment controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020-10-01

    Predicting future rates of tau accumulation on PET

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: In the cognitively unimpaired group, only higher baseline amyloid PET was a significant independent predictor of higher tau accumulation rates (P < 0.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-10-01

    The Effect of Adherence to the Mediterranean Diet on Late-Life Cognitive Disorders: A Systematic Review

    ✓ Peer-reviewed Prevention trials Journal of the American Medical Directors Association

    Key finding: The review's analysis confirmed that adherence to the MedDiet is associated with some improvement in cognitive health. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2020-10-01

    Approach to Cognitive Impairment in Parkinson's Disease

    ✓ Peer-reviewed Prevention trials Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

    Key finding: Dopaminergic medications and deep brain stimulation help motor dysfunction, but may have potential cognitive side effects. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →