Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 17,376–17,400 of 27,380 studies, newest first · page 696 of 1096.
January 2015 25
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2015-01-01
Insulin Resistance is Associated with Higher Cerebrospinal Fluid Tau Levels in Asymptomatic APOEɛ4 Carriers
45/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: IR among asymptomatic APOEɛ4 carriers was associated with higher P-Tau181 and T-Tau in late-middle age. +4 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Lithium as a Treatment for Alzheimer's Disease: A Systematic Review and Meta-Analysis
72/100 ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD
Key finding: The results indicate that lithium treatment may have beneficial effects on cognitive performance in subjects with MCI and AD dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Mediterranean Diet and Risk of Dementia
50/100 ✓ Peer-reviewed Prevention trials Current Alzheimer research
Key finding: Among the various dietary patterns that were tested for their effects on cognition, the traditional Mediterranean diet (MeDi) has shown promising results. +1 more finding
Full summary, score breakdown and related studies → Original source
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2015-01-01
Olive Oil Phenols as Promising Multi-targeting Agents Against Alzheimer's Disease
36/100 ✓ Peer-reviewed Prevention trials Advances in experimental medicine and biology
Key finding: Amyloid diseases are characterized by the deposition of typically aggregated proteins/peptides in tissues, associated with degeneration and progressive functional impairment. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Randomized controlled trial of a healthy brain ageing cognitive training program: effects on memory, mood, and sleep
72/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: The HBA-CT program improves cognitive, mood, and sleep functions in older adults 'at risk' of dementia, and therefore offers promise as a secondary prevention strategy.
Full summary, score breakdown and related studies → Original source
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2015-01-01
Dietary patterns and cognitive dysfunction in a 12-year follow-up study of 70 year old men
48/100 ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD
Key finding: We found no strong associations with development of cognitive dysfunction for any of the dietary patterns investigated. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Helicobacter pylori filtrate induces Alzheimer-like tau hyperphosphorylation by activating glycogen synthase kinase-3β
36/100 ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD
Key finding: The results showed that H. pylori filtrate induced significant tau hyperphosphorylation at several AD-related tau phosphorylation sites, such as Thr205, Thr231, and Ser404, both in mouse neuroblastoma N2a cells and rat brains with activation of glycogen synthase kinase-3β (GSK-3β). +1 more finding
Full summary, score breakdown and related studies → Original source
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2015-01-01
Synaptic therapy in Alzheimer's disease: a CREB-centric approach
36/100 ✓ Peer-reviewed Disease mechanisms Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Key finding: Disruption of these mechanisms in AD results in a reduction of CREB activation with accompanying memory impairment.
Full summary, score breakdown and related studies → Original source
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2015-01-01
Neurobiology of Alzheimer's Disease: Integrated Molecular, Physiological, Anatomical, Biomarker, and Cognitive Dimensions
40/100 ✓ Peer-reviewed Disease mechanisms Current Alzheimer research
Key finding: This review highlights the progression of biological changes underlying AD and their association with the clinical syndrome.
Full summary, score breakdown and related studies → Original source
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2015-01-01
Brain Aging in African-Americans: The Atherosclerosis Risk in Communities (ARIC) Experience
52/100 ✓ Peer-reviewed Long-term cohort studies Current Alzheimer research
Key finding: We will provide evidence from ARIC studies that disproportionate rates of vascular risk factors explain at least some of these observed disparities by race, but particular risk factors, including diabetes, may differentially affect the brain in African-American versus white participants.
Full summary, score breakdown and related studies → Original source
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2015 no date recorded — placed by publication year
Choice of Received Long-Term Care – Individual Responses to Regional Nursing Home Provisions
13/100 ⚠ Preprint — not yet peer-reviewed Health systems and care delivery Not indexed
Key finding: We find that the decision for long-term in-patient care is significantly correlated with the regional supply of nursing home places, while controlling for physical and psychological conditions of the individual.
Full summary, score breakdown and related studies → Original source
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2015 no date recorded — placed by publication year
Retail Grocery Evolution: What Can We Learn From Store Counts Data?
12/100 ⚠ Preprint — not yet peer-reviewed Risk factors Not indexed
Key finding: These results facilitate fast and reliable counterfactual simulations.
Full summary, score breakdown and related studies → Original source
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2015-01-01
Metabolic signals and innate immune activation in obesity and exercise
35/100 ✓ Peer-reviewed Prevention and risk Exercise immunology review
Key finding: Intensive research during the last two decades has revealed that a characteristic feature of obesity linking it to insulin resistance is the presence of chronic low-grade inflammation being indicative of activation of the innate immune system. +1 more finding
Full summary, score breakdown and related studies → Original source
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2015-01-01
Prevalence and Severity of Dementia in Nursing Home Residents
45/100 ✓ Peer-reviewed Health systems and care delivery Dementia and Geriatric Cognitive Disorders
Key finding: The odds of the occurrence and of a greater severity of dementia were higher in 2010/2011 than in 2004/2005. +2 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation?
43/100 ✓ Peer-reviewed Inflammation and the immune system Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Key finding: Among these, the association with Alzheimer disease has the strongest support. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
2003-2013: a decade of body mass index, Alzheimer's disease, and dementia
49/100 ✓ Peer-reviewed Brain tissue and pathology Journal of Alzheimer's disease : JAD
Key finding: The year 2013 marked a decade of epidemiologic observational reports on the association between BMI and late-onset dementias. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Latent Classes of Neuropsychiatric Symptoms in NACC Controls and Conversion to Mild Cognitive Impairment or Dementia
47/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: A number of studies have linked neuropsychiatric symptoms to increase risk of dementia. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Cognitive Impairment Precedes and Predicts Functional Impairment in Mild Alzheimer's Disease
60/100 ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD
Key finding: The temporal relationship of cognitive deficit and functional impairment in Alzheimer's disease (AD) is not well characterized. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Risk factors of caregiver burden among patients with Alzheimer's disease or related disorders: a cross-sectional study
53/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: Caregivers play a major role in the care of patients with dementia and are themselves at higher risk of disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Optimal cutoff scores for dementia and mild cognitive impairment of the Montreal Cognitive Assessment among elderly and oldest-old Chinese population
49/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: All versions of the Montreal Cognitive Assessment (MoCA) lack population-based data of 80-plus individuals. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease
72/100 ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD
Key finding: As tau aggregation pathology correlates with clinical dementia in Alzheimer's disease (AD), a tau aggregation inhibitor (TAI) could have therapeutic utility. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells
40/100 ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD
Key finding: While AD genetic studies implicate inflammation-relevant genes and fibrillar amyloid-β protein promotes inflammation, our understanding of AD neuroinflammation nevertheless remains incomplete. +3 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Auditory Verbal Learning Test is Superior to Rey-Osterrieth Complex Figure Memory for Predicting Mild Cognitive Impairment to Alzheimer's Disease
43/100 ✓ Peer-reviewed Mild cognitive impairment Current Alzheimer research
Key finding: The delayed recall of auditory verbal learning test (AVLT_DR) identified 116 subjects as MCI, resulted in the conversion rate as 44% over the roughly 30-month time interval, missed 7.8% incipient Alzheimer's disease (AD) patients in SCD group who eventually converted to dementia. +2 more findings
Full summary, score breakdown and related studies → Original source
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2015-01-01
Olfactory cortex degeneration in Alzheimer's disease and mild cognitive impairment
41/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: Decline in olfactory activity was correlated with the AD structural degeneration in the POC. +1 more finding
Full summary, score breakdown and related studies → Original source
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2015-01-01
Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease
45/100 ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD
Key finding: Individuals in the early stages of AD showed a significant decline in synaptic numbers compared to individuals with no cognitive impairment (NCI). +4 more findings
Full summary, score breakdown and related studies → Original source
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