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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 4,876–4,900 of 27,380 studies, newest first · page 196 of 1096.

March 2025 25

  1. 2025-03-21

    Cerebrovascular health impacts processing speed through anterior white matter alterations: a UK biobank study

    ✓ Peer-reviewed Long-term cohort studies Scientific Reports

    Key finding: Cerebrovascular disease is associated with an increased likelihood of developing dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2025-03-21

    Cerebrospinal fluid HSP90AA1, HSPA4, and STUB1/CHIP levels in Alzheimer's disease, mild cognitive impairment, and frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia Journal of Alzheimer s Disease

    Key finding: The STUB1/CHIP holds promise as a potential biomarker for distinguishing between SCI subjects, AD, and FTD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-03-21

    Alzheimer-typical temporo-parietal atrophy and hypoperfusion are associated with a more significant cholinergic impairment in amnestic neurodegenerative syndromes

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer s Disease

    Key finding: However, postmortem investigations indicate that the AD-typical progressive amnestic syndrome may also result from predominantly limbic non-AD neuropathology such as TDP-43 proteinopathy and argyrophilic grain disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2025-03-21

    Classification method based on surf and sift features for alzheimer diagnosis using diffusion tensor magnetic resonance imaging

    ✓ Peer-reviewed Brain scans and imaging Scientific Reports

    Key finding: Promising preliminary results demonstrate the potential of the proposed system as a useful tool to capture the AD leanness with achieving accuracies of 87.5%, 87.4%, 89%, and 95.2% for MD, FA, RD, and fusion of features respectively for the multiclass system using SIFT features. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2025-03-21

    Behavioural and cognitive profiles in frontotemporal dementia and Alzheimer’s disease: a longitudinal study

    ✓ Peer-reviewed Getting a diagnosis Journal of Neurology

    Key finding: Linear mixed modelling of time effects found progression of all CBI-R domains, aside from sleep, beliefs and mood domains, and all ACE-III domains. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-03-21

    Reliability and Validity of Self‐Reported Risk Factors for Stroke and Dementia

    ✓ Peer-reviewed Getting a diagnosis Journal of the American Heart Association

    Key finding: We used cross-sectional data from the NHANES (National Health and Nutrition Examination Survey) from 1999 to 2018 linked to National Death Index records. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2025-03-21

    Application of mini-mental state examination and Montreal Cognitive Assessment in the diagnosis of dementia with Lewy bodies and Alzheimer’s disease

    ✓ Peer-reviewed Getting a diagnosis Applied Neuropsychology Adult

    Key finding: We observed distinct cognitive performances in subjects from both the DLB and AD groups across different stages of dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2025-03-21

    Biomarkers in Contrast-Induced Nephropathy: Advances in Early Detection, Risk Assessment, and Prevention Strategies

    ✓ Peer-reviewed Prevention and risk International Journal of Molecular Sciences

    Key finding: Contrast-induced nephropathy (CIN) represents a significant complication associated with the use of iodinated contrast media (ICM), especially in individuals with preexisting renal impairment.

    Full summary, score breakdown and related studies → Original source

  9. 2025-03-21

    Digital gait biomarkers in Parkinson’s disease: susceptibility/risk, progression, response to exercise, and prognosis

    ✓ Peer-reviewed Prevention and risk npj Parkinson s Disease

    Key finding: The review of the literature to date suggests that upper body characteristics of gait (e.g., arm swing, trunk motion) may indicate susceptibility/risk of PD, while pace aspects (e.g., gait speed, stride length) are informative for tracking disease progression, exercise response, and fall likelihood.

    Full summary, score breakdown and related studies → Original source

  10. 2025-03-20

    Maximizing the benefit and managing the risk of anti-amyloid monoclonal antibody therapy for Alzheimer's disease: Strategies and research directions

    ✓ Peer-reviewed Treatments Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

    Key finding: Amyloid positron emission tomography reveals marked reductions in amyloid plaque burden; reductions below a threshold of 15-25 Centiloids are associated with clinical benefit. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2025-03-20

    Cerebrospinal fluid proteomics identification of biomarkers for amyloid and tau PET stages

    ✓ Peer-reviewed Brain scans and imaging Cell reports. Medicine

    Key finding: These signatures outperform the established CSF biomarkers (area under the curve [AUC]: 0.92 versus 0.67-0.70) and accurately predicted disease progression over a decade. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2025-03-20

    Mapping the impact of age and APOE risk factors for late onset Alzheimer's disease on long range brain connections through multiscale bundle analysis

    ✓ Peer-reviewed Risk factors Brain structure & function

    Key finding: We found that the third level subdivision in the bundle hierarchy provided the most sensitive ability to detect age and genotype differences associated with risk factors. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2025-03-20

    Associations of KLOTHO-VS heterozygosity and α-Klotho protein with cerebrospinal fluid Alzheimer's disease biomarkers

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer s Disease

    Key finding: KL -VSHET may help protect against amyloid pathology, particularly in the presence of APOE ε4, and regardless of APOE status in aMCI-AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2025-03-20

    Rock inhibitors in Alzheimer’s disease

    ✓ Peer-reviewed Disease mechanisms Frontiers in Aging

    Key finding: Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and cause of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2025-03-20

    Neuroprotective effects of SGLT2 inhibitors empagliflozin and dapagliflozin on Aβ 1–42 -induced neurotoxicity and neuroinflammation in cellular models of Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer s Disease

    Key finding: SGLT2i empagliflozin and dapagliflozin exhibited neuroprotective actions against human Aβ 1–42 -induced neurotoxicity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2025-03-20

    Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD mice

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in Pharmacology

    Key finding: IBC effectively ameliorates AD pathology through autophagy-mediated clearance of Aβ and suppressing neuroinflammation in 5x-FAD mice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2025-03-20

    Mediation Analyses Link Cardiometabolic Factors and Liver Fat With White Matter Hyperintensities and Cognitive Performance: A UK Biobank Study

    ✓ Peer-reviewed Long-term cohort studies Biological Psychiatry Global Open Science

    Key finding: Our findings indicate that liver fat mediates associations between cardiometabolic factors and WMHs and that WMHs mediate the association between liver fat and cognitive performance. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2025-03-20

    TBG096 Ameliorates Memory Deficiency in AD Mouse Model via Promoting Neurogenesis and Regulation of Hsc70/HK2/PKM2/LAMP2A Signaling Pathway

    ✓ Peer-reviewed Risk genes beyond APOE International Journal of Molecular Sciences

    Key finding: Recently, a lead compound named TBG096 was discovered with significant NGF-mimic activity, low toxicity, and ability to pass through the blood–brain barrier (BBB). +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-03-20

    Altered face perception in amnestic mild cognitive impairment: Evidence from representational similarity analysis of event-related potential

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer s Disease

    Key finding: Also, compared to HCs, aMCI patients exhibited a lack of right hemisphere advantage in N170 in response to faces. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2025-03-20

    Identifying Exercise Interventions That May Slow the Progression of Cognitive Decline in Older Adults With Mild Cognitive Impairment: A Scoping Review

    ✓ Peer-reviewed Mild cognitive impairment Cureus

    Key finding: Symptoms of MCI can include problems with thinking, judgment, memory, and language, but the loss does not significantly interfere with the ability to handle everyday activities. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2025-03-20

    Dopaminergic changes in the subgenual cingulate cortex in dementia with lewy bodies associates with presence of depression

    ✓ Peer-reviewed Lewy body dementia Translational Psychiatry

    Key finding: STED imaging demonstrated the presence of α-synuclein within individual dopaminergic terminals in the sgACC, α-synuclein presence showing a significant positive correlation with increased synaptosomal associated protein 25 kDa (SNAP25) volumes in depressed DLB cases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2025-03-20

    Autonomic Dysfunction in Patients With Dementia With Lewy Bodies and Its Relationship With Nigrostriatal Denervation

    ✓ Peer-reviewed Lewy body dementia Neurology

    Key finding: Despite the absence of overt nOH, patients with DLB show covert dysautonomia encompassing adrenergic, parasympathetic, and sudomotor dysfunction, highlighting the importance of standardized autonomic evaluation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2025-03-20

    The role of autophagy in the pathogenesis and treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)

    ✓ Peer-reviewed Lewy body dementia Autophagy Reports

    Key finding: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two extremes of a neurodegenerative disease spectrum characterised by overlapping genetic, clinical, and neuropathological features. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2025-03-20

    Physical exercise and epigenetic modifications in skeletal muscle, brain, and heart

    ✓ Peer-reviewed Prevention and risk Epigenetics & Chromatin

    Key finding: Epigenetic modifications have recently gained prominence as a significant mediator between genetic information and environmental factors, influencing the occurrence and progression of disease.

    Full summary, score breakdown and related studies → Original source

  25. 2025-03-20

    Hearing Loss and Falls

    ✓ Peer-reviewed Prevention and risk JAMA Otolaryngology–Head & Neck Surgery

    Key finding: A total of 5 071 935 participants were included from 27 studies; approximately 49.2% of participants were female, and 14 studies were conducted in Asia, 7 in North America, 3 in Europe, and 3 in Oceania, represented by Australia. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →