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Medical Care of Adults With Down Syndrome: A Clinical Guideline
Tsou AY, Bulova P, Capone G, Chicoine B, Gelaro B, Harville TO, Martin BA, McGuire DE et al.. JAMA, 2020-10-01
Topic: Risk, prevention and care in population studies
Findings From 11 295 literature citations associated with 10 PICO questions, 20 relevant studies were identified.
Key findings
- Findings From 11 295 literature citations associated with 10 PICO questions, 20 relevant studies were identified.
Why it matters
This clinical guideline identified 20 relevant studies from 11,295 literature citations on medical care of adults with Down syndrome. It provides no findings in the given text about treating, curing, or preventing Alzheimer's disease.
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Study details
- Participants13
- Evidence strengthLow
How this study scored 59/100
Published in a top-tier journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 57 of the 96 points we could judge it on, which is 59 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 10 / 10 | Tier 1 — top-tier general journal (JAMA) |
| Journal's citation record | 4 / 4 | JAMA: journal h-index 1,011 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2020 — within 10 year(s) of the newest study here |
| Sample size | 1 / 4 | 13 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 5 / 7 | Cited 206 times (OpenAlex, 2026-10-10) |
| Citations per year | 4 / 5 | 25.8 citations a year over 8 year(s) since 2020 |
| Impact for its field and year | 4 / 6 | Cited 16.2× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 3 / 6 | Cited by 10 other studies in this library |
| Still being cited | 3 / 4 | Cited 112 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | — / 4 | OpenAlex's profile for last-listed author Michelle Sie Whitten holds only 4 work(s), too few to judge a track record — left out of this score |
| Institution's track record | 2 / 3 | Johns Hopkins University: institution h-index 2,306 (OpenAlex) |
| Multi-centre collaboration | 3 / 3 | OpenAlex lists 11 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 33079159) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 57 / 96 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 57 of the 96 points we could judge it on is 59 out of 100. |
| Total | 59 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
May need a subscription OpenAlex found no free copy of the full text (checked 6 Feb 1020), so the publisher may charge for it. The PubMed abstract is free.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Tsou, A. Y., Bulova, P., Capone, G., Chicoine, B., Gelaro, B., Harville, T. O., et al. (2020). Medical Care of Adults With Down Syndrome: A Clinical Guideline. JAMA. https://doi.org/10.1001/jama.2020.17024
Vancouver
Tsou AY, Bulova P, Capone G, Chicoine B, Gelaro B, Harville TO, et al. Medical Care of Adults With Down Syndrome: A Clinical Guideline. JAMA. 2020. doi:10.1001/jama.2020.17024. PMID: 33079159.
BibTeX
@article{tsou2020-33079159,
author = {Tsou, A. Y. and Bulova, P. and Capone, G. and Chicoine, B. and Gelaro, B. and Harville, T. O. and Martin, B. A. and McGuire, D. E. and others},
title = {{Medical Care of Adults With Down Syndrome: A Clinical Guideline}},
journal = {JAMA},
year = {2020},
doi = {10.1001/jama.2020.17024},
pmid = {33079159},
url = {https://doi.org/10.1001/jama.2020.17024}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.
Later studies that cite this one
10 studies in the alzhub library list this one in their references. Showing the 8 highest-scoring.
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Also tagged “down”
527 studies in the library carry the topic tag “down”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 527 tagged studies.