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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,476–10,500 of 27,380 studies, newest first · page 420 of 1096.

March 2021 8

  1. 2021-03-01

    Coronavirus disease 2019 and neurodegenerative disease: what will the future bring?

    ✓ Peer-reviewed Inflammation and the immune system Current opinion in psychiatry

    Key finding: Further studies are needed to determine whether COVID-19 may lead to an increased risk of developing NDD in susceptible individuals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-03-01

    Lamotrigine and Stevens-Johnson Syndrome Prevention

    ✓ Peer-reviewed Prevention and risk Psychopharmacology Bulletin

    Key finding: Furthermore, patients of Japanese origin with HLAB*31:01 and Koreans with HLA-B*44:03 are also at increased risk of SJS after receiving the same two drugs. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2021-03-01

    Neurogranin as a Novel Biomarker in Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Laboratory medicine

    Key finding: In this study, we investigated the possible role of 2 novel biomarkers of synaptic damage, namely, neurogranin and α-synuclein, in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-03-01

    Dementia Caregiving During the "Stay-at-Home" Phase of COVID-19 Pandemic

    ✓ Peer-reviewed Disparities The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: Use of the transactional model of stress responses yielded important insights about families coping with dementia.

    Full summary, score breakdown and related studies → Original source

  5. 2021-03-01

    Trends in Relative Incidence and Prevalence of Dementia Across Non-Hispanic Black and White Individuals in the United States, 2000-2016

    ✓ Peer-reviewed Disparities JAMA neurology

    Key finding: This study did not find evidence to suggest that the ratio of dementia risk across Black and White individuals changed in the US between 2000 and 2016. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-03-01

    Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: Kaplan-Meier analysis showed that patients with IRBD who were α-synuclein negative had lower risk for developing Parkinson's disease or dementia with Lewy bodies at 2, 4, 6, 8, and 10 years of follow-up than patients with IRBD who were α-synuclein positive (log-rank test p=0·028; hazard ratio 0·143, 95% CI 0·019-1·063). +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2021-03-01

    Hormonal and Metabolic Changes of Aging and the Influence of Lifestyle Modifications

    ✓ Peer-reviewed Prevention and risk Mayo Clinic proceedings

    Key finding: Unfortunately, hormone replacement therapy is not a panacea, as it often results in various adverse events that outweigh its potential health benefits.

    Full summary, score breakdown and related studies → Original source

  8. 2021-03-01

    Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial

    ✓ Peer-reviewed Treatments JAMA neurology

    Key finding: change from baseline in Preclinical Alzheimer Cognitive Composite score. +4 more findings

    Full summary, score breakdown and related studies → Original source

February 2021 17

  1. 2021-02-28

    Early-onset familial Alzheimer's disease in a family with mutation of presenilin 2 gene

    ✓ Peer-reviewed Risk genes beyond APOE Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

    Key finding: A family with a total of 3 patients were admitted to the Department of Neurology of Xiangya Hospital, Central South University in 2018. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-02-27

    The oralome and its dysbiosis: New insights into oral microbiome-host interactions

    ✓ Peer-reviewed Disease mechanisms Computational and structural biotechnology journal

    Key finding: However, the microbial composition is significantly affected by interspecies and host-microbial interactions, which in turn, can impact the health and disease status of the host. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2021-02-27

    The Bidirectional Relationship between Vision and Cognition: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Risk factors Ophthalmology

    Key finding: Topic Visual impairment (VI) and cognitive impairment (CIM) are prevalent age-related conditions that impose substantial burden on the society. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2021-02-27

    Burden of illness among patients with dementia-related psychosis

    ✓ Peer-reviewed Health systems and care delivery Journal of Managed Care & Specialty Pharmacy

    Key finding: A significantly higher percentage of DRP patients had ≥1 diagnosis for behavioral health conditions in the pre-index period compared with dementia-only patients (depression: 32.4% vs. 22.8%; anxiety: 19.1% vs. 11.5%; and insomnia: 9.0% vs. 6.3%; P < 0.001 for all comparisons). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-02-26

    Cholesterol profiles and incident cognitive decline among older adults: the Shanghai Aging Study

    ✓ Peer-reviewed Risk factors Age and ageing

    Key finding: among VRFs-free participants, TC (HR 0.62, 95%CI 0.40-0.95) and LDL-C (HR 0.47, 95%CI 0.28-0.80) were inversely associated with incident dementia, LDL-C was inversely associated with incident AD (HR 0.50, 95%CI 0.28-0.90). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2021-02-26

    C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels

    ✓ Peer-reviewed Drug development Autophagy

    Key finding: We suggest that dysfunction of the autophagy-lysosome pathway synergizes with toxicity from C9orf72 repeat RNA and DPRs to drive disease pathogenesis.

    Full summary, score breakdown and related studies → Original source

  7. 2021-02-26

    Clinical Relevance of [18F]Florbetaben and [18F]FDG PET/CT Imaging on the Management of Patients with Dementia

    ✓ Peer-reviewed Tau biomarkers Molecules (Basel, Switzerland)

    Key finding: The aim of this retrospective analysis was to evaluate clinical relevance of [ 18 F ] FBB, [ 18 F ] FDG PET and complimentary CSF measurements in patients with suspected dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2021-02-26

    Targeting Microglia-Synapse Interactions in Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics International journal of molecular sciences

    Key finding: We present evidence that ramified microglia, classically believed to be "resting" (i.e., inactive), are instead strongly implicated in dynamic and plastic processes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-02-26

    Using a distribution-based approach and systematic review methods to derive minimum clinically important differences

    ✓ Peer-reviewed Treatments BMC medical research methodology

    Key finding: A distribution-based approach using data included in a systematic review approximated known MCIDs. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-02-25

    Artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in MPP+-treated SH-SY5Y cells

    ✓ Peer-reviewed Disease mechanisms Journal of biological research (Thessalonike, Greece)

    Key finding: No significant cytotoxicity was observed at ART concentrations up to 40 μM. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-02-25

    Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis

    ✓ Peer-reviewed Treatments BMJ (Clinical research ed.)

    Key finding: Pooled evidence from available trials reporting both reduction in amyloid levels and change in cognition suggests that amyloid reduction strategies do not substantially improve cognition. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-02-25

    Endosome Dysregulation in Down Syndrome: A Potential Contributor to Alzheimer Disease Pathology

    ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of neurology

    Key finding: Studies have shown that the majority of Down syndrome subjects develop AD pathology and manifest altered morphology and number of endosomes, and abnormalities in lysosome acidification and exosome secretion, suggesting that dysfunction of one of these pathways could play a functional role in the AD-like phenotype of the syndrome.

    Full summary, score breakdown and related studies → Original source

  13. 2021-02-24

    Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages

    ✓ Peer-reviewed TREM2 and immune genetics Diabetes

    Key finding: Overexpression of the triggering receptor expressed on myeloid cells 2 (TREM2) reportedly increases adiposity, worsening health. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-02-24

    Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1

    ✓ Peer-reviewed TREM2 and immune genetics Brain, behavior, & immunity - health

    Key finding: Alzheimer's disease (AD) is associated with abnormal tau and amyloid-β accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and extracellular amyloid-β plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-02-24

    A Risk Prediction Model Based on Machine Learning for Cognitive Impairment Among Chinese Community-Dwelling Elderly People With Normal Cognition: Development and Validation Study

    ✓ Peer-reviewed Digital health tools Journal of medical Internet research

    Key finding: This simple and feasible cognitive impairment prediction model could identify community-dwelling elderly people at the greatest 3-year risk for cognitive impairment, which could help community nurses in the early identification of dementia.

    Full summary, score breakdown and related studies → Original source

  16. 2021-02-24

    Association of Memory Impairment With Concomitant Tau Pathology in Patients With Cerebral Amyloid Angiopathy

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: These results suggest that the presence of objective memory impairment in patients with probable CAA could serve as a marker for underlying tau pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2021-02-23

    Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Molecular imaging and biology

    Key finding: Transgenic animals displayed higher total exposure, calculated as the AUC based on SUV determined at 24h, 48h, and 72h post injection, of PET radioligand [124I]mAb1729-scFv8D3CL than WT mice. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →