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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,026–10,050 of 27,380 studies, newest first · page 402 of 1096.

July 2021 23

  1. 2021-07-03

    Understanding Elderspeak: An Evolutionary Concept Analysis

    ✓ Peer-reviewed Digital health tools Innovation in aging

    Key finding: Eighty-three theoretical or research articles from 1981 to 2020 were identified.

    Full summary, score breakdown and related studies → Original source

  2. 2021-07-02

    Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Free radical biology & medicine

    Key finding: Emerging evidence suggests that misfolded proteins accumulate in the diseased brain at least in part as a consequence of excessively generated reactive oxygen species (ROS) and reactive nitrogen species (RNS).

    Full summary, score breakdown and related studies → Original source

  3. 2021-07 month only

    Aducanumab and disease modifying treatments for Alzheimer's disease

    ✓ Peer-reviewed Treatments Progress in Neurology and Psychiatry

    Key finding: Aducanumab has recently been licensed by the Food and Drug Administration (FDA) in the USA under its ‘accelerated approval’ pathway (to provide earlier access to treatments that fulfil an unmet need based on a surrogate endpoint) for treatment of Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  4. 2021-07 month only

    Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial

    ✓ Peer-reviewed Clinical trials The Lancet. Neurology

    Key finding: Between Aug 28, 2013, and Dec 21, 2015, we enrolled 3494 participants (3061 at high risk and 433 at low risk). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2021-07-01

    [18F]Flortaucipir PET Across Various MAPT Mutations in Presymptomatic and Symptomatic Carriers

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: [18F]Flortaucipir BPND images showed overall highest binding in the symptomatic carriers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2021-07-01

    Plasmonic Interferometers as TREM2 Sensors for Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Biosensors

    Key finding: We report an effective surface immobilization protocol for capture of Triggering Receptor Expressed on Myeloid Cells 2 (TREM2), a receptor whose elevated concentration in cerebrospinal fluid has recently been associated with Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2021-07-01

    Healthy Aging-Nutrition Matters: Start Early and Screen Often

    ✓ Peer-reviewed Risk factors Advances in nutrition (Bethesda, Md.)

    Key finding: This narrative review summarizes consistent evidence indicating that healthy dietary patterns and maintenance of a healthy weight in the years leading to old age are associated with broad prevention of all the archetypal diseases and impairments associated with aging including: noncommunicable diseases, sarcopenia, cognitive decline and dementia, osteoporosis, age-related macular degeneration, diabetic retinopathy, hearing loss, obstructive sleep apnea, urinary incontinence, and constipation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2021-07-01

    Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial

    ✓ Peer-reviewed Treatments JAMA network open

    Key finding: Racial/ethnic groups differed in sources of recruitment, reasons for screen failure, and overall probability of eligibility in a preclinical AD trial. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2021-07-01

    Change in CAIDE Dementia Risk Score and Neuroimaging Biomarkers During a 2-Year Multidomain Lifestyle Randomized Controlled Trial: Results of a Post-Hoc Subgroup Analysis

    ✓ Peer-reviewed Prevention trials The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: It was previously associated with imaging biomarkers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2021-07-01

    Going back home digitally: gift for patients with end-stage heart failure

    ✓ Peer-reviewed Risk factors European Heart Journal - Digital Health

    Key finding: Fortunately, in our experience, five of the six patients were likely to be satisfied with these digital experiences. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2021-07-01

    Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia

    ✓ Peer-reviewed Inflammation and the immune system Cell reports

    Key finding: However, the underlying mechanism of TauO-induced aging-related neuroinflammation remains unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2021-07-01

    [Aducanumab and Alzheimer's disease: a critical reflection.]

    ✓ Peer-reviewed Drug development Recenti progressi in medicina

    Key finding: This decision was achieved through the Accelerated Approval Pathway and was essentially motivated by the evidence that aducanumab reduces brain amyloid plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2021-07-01

    Alzheimer's trials: A cul-de-sac with no end in sight

    ✓ Peer-reviewed Drug development Advances in clinical and experimental medicine : official organ Wroclaw Medical University

    Key finding: The absence of disease-modifying treatments for Alzheimer today is due to the amyloid hypothesis, a misguided hypothesis of Alzheimer’s disease etiology, which has dominated Alzheimer research, drug development, and clinical trials for 30 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2021-07-01

    Amyloid and tau positive mild cognitive impairment: clinical and biomarker characteristics of dementia progression

    ✓ Peer-reviewed Tau biomarkers Chinese medical journal

    Key finding: According to the amyloid, tau, neurodegeneration research framework classification, amyloid and tau positive (A+T+) mild cognitive impairment (MCI) individuals are defined as prodromal Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2021-07-01

    Acute Trem2 reduction triggers increased microglial phagocytosis, slowing amyloid deposition in mice

    ✓ Peer-reviewed TREM2 and immune genetics Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Amyloid beta-depositing mouse models haploinsufficient or null for Trem2 have identified important relationships among TREM2, microglia, and AD pathology; however, results are challenging to interpret in the context of varying microglial phenotypes and disease progression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2021-07-01

    An Update on Medical and Surgical Treatments of Parkinson's Disease

    ✓ Peer-reviewed Digital health tools Aging and disease

    Key finding: Management of PD is complex but there have been significant advancements in the treatment of motor and non-motor symptoms over the past few years.

    Full summary, score breakdown and related studies → Original source

  17. 2021-07-01

    Machine learning for modeling the progression of Alzheimer disease dementia using clinical data: a systematic literature review

    ✓ Peer-reviewed Digital health tools JAMIA open

    Key finding: Identifying individuals at risk for progression of AD dementia could potentially help to personalize disease management to plan future care. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2021-07-01

    Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative

    ✓ Peer-reviewed Digital health tools JAMA network open

    Key finding: This cohort study found that COVID-19 mortality decreased over time during 2020 and that patient demographic characteristics and comorbidities were associated with higher clinical severity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2021-07-01

    Parkinson disease-associated cognitive impairment

    ✓ Peer-reviewed How common it is Nature reviews. Disease primers

    Key finding: Other risk factors for early progression to dementia include visual hallucinations, older age and biomarker changes such as cortical atrophy, as well as Alzheimer-type changes on functional imaging and in cerebrospinal fluid, and slowing and frequency variation on EEG. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2021-07-01

    Systematic Review and Meta-Analysis of Racial and Ethnic Differences in Dementia Caregivers' Well-Being

    ✓ Peer-reviewed Disparities The Gerontologist

    Key finding: Random-effects models revealed small but statistically significant effects with better psychological well-being in African American caregivers compared with white caregivers in both population-based (d = -0.22) and convenience sample studies (d = -0.21). +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2021-07-01

    Impact of dementia: Health disparities, population trends, care interventions, and economic costs

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Significant research gaps remain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2021-07-01

    Meat consumption and risk of incident dementia: cohort study of 493,888 UK Biobank participants

    ✓ Peer-reviewed Genetics The American journal of clinical nutrition

    Key finding: Worldwide, the prevalence of dementia is increasing and diet as a modifiable factor could play a role. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2021-07-01

    Association of Sleep and β-Amyloid Pathology Among Older Cognitively Unimpaired Adults

    ✓ Peer-reviewed Biomarkers JAMA network open

    Key finding: Amyloid PET and sleep duration information was acquired on 4425 cognitively unimpaired participants (mean [SD] age, 71.3 [4.7] years; 2628 [59.4%] female; 1509 [34.1%] tested Aβ positive). +3 more findings

    Full summary, score breakdown and related studies → Original source

June 2021 2

  1. 2021-06-30

    Aducanumab for Alzheimer's disease: An update

    ✓ Peer-reviewed Treatments Neuroscience Research Notes

    Key finding: The US FDA approved Aducanumab in June 2021 as the first Alzheimer's disease (AD) drug under its accelerated approval pathway. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2021-06-30

    Metabolic Syndrome: Is It Time to Add the Central Nervous System?

    ✓ Peer-reviewed Risk factors Nutrients

    Key finding: IR can affect multiple tissues and organs, from the classic "triumvirate" (myocyte, adipocyte, and hepatocyte) to possible effects on organs considered more recently, such as the central nervous system (CNS). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →