alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,376–7,400 of 27,380 studies, newest first · page 296 of 1096.

September 2023 25

  1. 2023-09-06

    Plasma Neurofilament Light Chains as Blood-Based Biomarkers for Early Diagnosis of Canine Cognitive Dysfunction Syndrome

    ✓ Peer-reviewed Biomarkers International journal of molecular sciences

    Key finding: The number of elderly dogs is increasing significantly worldwide, and many elderly dogs develop canine cognitive dysfunction syndrome (CCDS). +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-09-06

    Plasma Alzheimer's biomarkers and brain amyloid in Hispanic and non-Hispanic older adults

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Three-hundred seventy nine participants underwent blood draw (71.9 ± 7.8 years old, 60.2% female, 57% Hispanic of which 88% were Cuban or South American) and 240 completed Aβ-PET.

    Full summary, score breakdown and related studies → Original source

  3. 2023-09-05

    Caregiver experiences of hospice dementia care: a systematic review and meta-ethnography

    ✓ Peer-reviewed End-of-life care Aging & mental health

    Key finding: Two third-order constructs were generated through meta-ethnography: expectations of care and barriers to quality of care. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-09-05

    Targeting NLRP3 inflammasome for neurodegenerative disorders

    ✓ Peer-reviewed Inflammation and the immune system Molecular psychiatry

    Key finding: The studies suggest that targeting NLRP3 inflammasome could be a novel approach for the disease modification.

    Full summary, score breakdown and related studies → Original source

  5. 2023-09-05

    Hypertension and Stroke as Mediators of Air Pollution Exposure and Incident Dementia

    ✓ Peer-reviewed Risk factors JAMA network open

    Key finding: Among 27 857 participants (mean [SD] age at baseline, 61 [10] years; 15 747 female participants [56.5%]; 19 249 non-Hispanic White participants [69.1%]), 4105 (14.7%) developed dementia during the follow-up period (mean [SD], 10.2 [5.6] years). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023-09-05

    Health care utilization before and after a dementia diagnosis in Medicare Advantage versus traditional Medicare

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: Among 454,508 beneficiaries diagnosed with ADRD in 2017, 250,837 (55%) were in TM and 203,671 (45%) in MA. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-09-05

    Video Intervention and Goals-of-Care Documentation in Hospitalized Older Adults: The VIDEO-PCE Randomized Clinical Trial

    ✓ Peer-reviewed Treatments JAMA network open

    Key finding: Goals-of-care documentation during the intervention phase occurred among 3744 of 6023 patients (62.2%) compared with 2396 of 4779 patients (50.1%) in the usual care phase (P Conclusions and relevance In this stepped-wedge cluster randomized clinical trial of older adults, a GOC video intervention delivered by PCEs resulted in higher rates of GOC documentation compared with usual care, including among Black or African American individuals, Hispanic or Latino individuals, non-English speakers, and people living with Alzheimer disease and related dementias. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-09-04

    Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists

    ✓ Peer-reviewed Drug development Theranostics

    Key finding: The cross-linking pathways between diabetes and dementia suggest that antidiabetic medications can potentially treat dementia.

    Full summary, score breakdown and related studies → Original source

  9. 2023-09-04

    Aging Exacerbates Oxidative Stress and Liver Fibrosis in an Ani-Mal Model of Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Aging

    Key finding: Oxidative stress in DS is associated with neurodevelopmental defects, neuronal dysfunction, and the onset of dementia re-sembling Alzheimer's disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2023-09-04

    Emerging diagnostics and therapeutics for Alzheimer disease

    ✓ Peer-reviewed Treatments Nature medicine

    Key finding: We review recent results that enable pathological staging of AD with neuroimaging and fluid-based biomarkers, with a particular emphasis on the role of amyloid, tau and neuroinflammation in disease pathogenesis.

    Full summary, score breakdown and related studies → Original source

  11. 2023-09-02

    Determining Evidence for Family Caregiver Communication: Associating Communication Behaviors With Breakdown and Repair

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Breakdown (coded as 0) was associated with caregivers changing topic (median = -11.45, 95% credibility interval [CrI; -24.34, -4.37]), ignoring (median = -11.49, 95% CrI [-24.49, -4.72]), giving commands (median = -10.74, 95% CrI [-24.22, -3.38]), and taking over the task (median = -4.06, 95% CrI [-7.28, -1.77]). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2023-09-02

    Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial

    ✓ Peer-reviewed Prevention and risk The Lancet

    Key finding: 977 adults aged 70-84 with untreated hearing loss randomized to hearing intervention (counseling + hearing aids) vs. health education control +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-09 month only

    Health Care Costs Associated With Hospice Use For People With Dementia In The US

    ✓ Peer-reviewed Costs and economics Health affairs (Project Hope)

    Key finding: Yet this perspective fails to incorporate potential cost savings associated with hospice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2023-09 month only

    Exploring factors contributing to caregiver burden in family caregivers of congolese adults with suspected dementia

    ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry

    Key finding: Average caregiver burden on the ZBI was 36.1 (SD = 14.6; range = 12-58). +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-09 month only

    Effects of lithium on serum Brain-Derived Neurotrophic Factor in Alzheimer's patients with agitation

    ✓ Peer-reviewed Drug development International journal of geriatric psychiatry

    Key finding: BDNF levels did not change significantly and were not associated with improvement in overall neuropsychiatric symptoms or in cognitive function. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2023-09 month only

    Lecanemab (Leqembi) is not the right drug for patients with Alzheimer's disease

    ✓ Peer-reviewed Treatments Advances in clinical and experimental medicine : official organ Wroclaw Medical University

    Key finding: This is especially significant because women have a twofold increased risk of AD compared to men, that is, there are 2 times more women than men living with AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2023-09-01

    Genome-wide association study of abnormal elevation of ALT in patients exposed to atabecestat

    ✓ Peer-reviewed Genetics BMC genomics

    Key finding: No variant passed the genome-wide significance threshold (p = 5 × 10- 8) in the case-control GWAS. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-09-01

    Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion

    ✓ Peer-reviewed Genetics Cell

    Key finding: We develop methods for multimodal integration and detecting regulatory modules using peak-to-gene linking. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-09-01

    Early Alzheimer's disease pathology in human cortex involves transient cell states

    ✓ Peer-reviewed Genetics Cell

    Key finding: Finally, both oligodendrocytes and pyramidal neurons upregulated genes associated with β-amyloid production and processing during this early hyperactive phase.

    Full summary, score breakdown and related studies → Original source

  20. 2023-09-01

    Human microglial state dynamics in Alzheimer's disease progression

    ✓ Peer-reviewed Genetics Cell

    Key finding: Overall, we provide insights underlying microglial states, including state-specific and AD-stage-specific microglial alterations at unprecedented resolution.

    Full summary, score breakdown and related studies → Original source

  21. 2023-09-01

    Combined exercise and cognitive interventions for adults with mild cognitive impairment and dementia: A systematic review and network meta-analysis

    ✓ Peer-reviewed Prevention trials International journal of nursing studies

    Key finding: This review suggests the advantage of combined interventions over exercise with comparable effects when compared with cognitive interventions in the population with mild cognitive impairment and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-09-01

    Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology

    ✓ Peer-reviewed Brain tissue and pathology Cell

    Key finding: To address this, we generated a single-cell transcriptomic atlas of the aged human prefrontal cortex covering 2.3 million cells from postmortem human brain samples of 427 individuals with varying degrees of AD pathology and cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2023-09-01

    Sedentary Behavior and Incident Dementia Among Older Adults

    ✓ Peer-reviewed Digital health tools JAMA

    Key finding: During this time, 414 individuals were diagnosed with incident all-cause dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2023-09-01

    Dementia Risk and Disadvantaged Neighborhoods

    ✓ Peer-reviewed Disparities JAMA neurology

    Key finding: Among the 1 637 484 Veterans Health Administration patients, the mean (SD) age was 68.6 (7.7) years, and 1 604 677 (98.0%) were men. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2023-09-01

    Amyloid-related Imaging Abnormalities in Alzheimer Disease Treated with Anti-Amyloid-β Therapy

    ✓ Peer-reviewed Brain scans and imaging Radiographics : a review publication of the Radiological Society of North America, Inc

    Key finding: ARIA is thought to be caused by increased vascular permeability following an inflammatory response, leading to the extravasation of blood products and proteinaceous fluid. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →