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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,651–8,675 of 27,380 studies, newest first · page 347 of 1096.

July 2022 25

  1. 2022-07-21

    Inhibition of Microtubule Affinity Regulating Kinase 4 by Metformin: Exploring the Neuroprotective Potential of Antidiabetic Drug through Spectroscopic and Computational Approaches

    ✓ Peer-reviewed Drug development Molecules (Basel, Switzerland)

    Key finding: MARK4 is known for its major role in tau phosphorylation via phosphorylating Ser262 residue in the KXGS motif, which results in the detachment of tau from microtubule. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-07-21

    Hippocampus- and thalamus-related fiber-specific white matter reductions in mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Cerebral cortex (New York, N.Y. : 1991)

    Key finding: Early diagnosis of mild cognitive impairment (MCI) fascinates screening high-risk Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2022-07-21

    Early-phase 18F-Florbetapir and 18F-Flutemetamol images as proxies of brain metabolism in a memory clinic setting

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: Positive correlations were found between eFBP/eFMM and 18F-FDG-PET SUVR independently of Aβ status and Aβ radiotracer (R>0.72, p<0.001). eFBP/eFMM single-subject analysis revealed clusters of significant hypoperfusion with good correspondence to hypometabolism topographies, independently of the underlying neurodegenerative patterns. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2022-07-21

    If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?

    ✓ Peer-reviewed Treatments PLoS biology

    Key finding: Microglia that are potentially involved in alternative mechanisms are actually integral to the amyloid cascade. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-07-21

    Plasma Aβ42/40 ratio, p-tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross-sectional and longitudinal study in the AIBL cohort

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These findings suggest that plasma biomarkers are altered cross-sectionally and longitudinally, along the AD continuum, and are prospectively associated with cognitive decline and brain Aβ-PET load. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-07-21

    A Machine-Learning Based Approach for Predicting Older Adults' Adherence to Technology-Based Cognitive Training

    ✓ Peer-reviewed Prevention trials Information processing & management

    Key finding: In this study we built machine learning models to predict participants' adherence at different levels (overall and weekly) using data collected from a previous cognitive training intervention. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2022-07-21

    Mediterranean Diet on Sleep: A Health Alliance

    ✓ Peer-reviewed Prevention trials Nutrients

    Key finding: The Mediterranean diet is a plant-based, antioxidant-rich, unsaturated fat dietary pattern that has been consistently associated with lower rates of noncommunicable diseases and total mortality, so that it is considered one of the healthiest dietary patterns. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2022-07-21

    [The Cost of Early Diagnosis of Cognitive Decline in German Memory Clinics]

    ✓ Peer-reviewed Health systems and care delivery Fortschritte der Neurologie-Psychiatrie

    Key finding: This results in total average costs of € 1.394,43 per case as the mean across all centres (personnel costs € 351,72, costs for diagnostic procedures € 1.042,71). +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2022-07-21

    The hearing hippocampus

    ✓ Peer-reviewed Digital health tools Progress in neurobiology

    Key finding: In examining imaging, recording, and lesion studies in species from rodents to humans, we uncover a hierarchy of hippocampal responses to sound including during passive exposure, active listening, and the learning of associations between sounds and other stimuli. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2022-07-21

    Blots on a field?

    ✓ Peer-reviewed Laboratory science Science

    Key finding: Independent forensic analysts (Elisabeth Bik, Jana Christopher) identified apparent duplicated bands and composited images across roughly 20 of Lesné's papers, about 10 involving Aβ*56 +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2022-07-20

    Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration

    ✓ Peer-reviewed TREM2 and immune genetics Cell death & disease

    Key finding: A common feature of some of these activated phenotypes is the upregulation of galectin-3. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2022-07-20

    Cognability: An Ecological Theory of neighborhoods and cognitive aging

    ✓ Peer-reviewed Disparities Social science & medicine (1982)

    Key finding: Access to civic and social organizations, recreation centers, fast-food and coffee establishments, arts centers, museums, and highways were significantly associated with cognitive function. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2022-07-20

    [Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]

    ✓ Peer-reviewed Biomarkers Fortschritte der Neurologie-Psychiatrie

    Key finding: Determining blood biomarkers represents less invasive and less costly diagnostics for Alzheimer´s disease.

    Full summary, score breakdown and related studies → Original source

  14. 2022-07-19

    Olfactory Bulb Amyloid-β Correlates With Brain Thal Amyloid Phase and Severity of Cognitive Impairment

    ✓ Peer-reviewed Clinical trials Journal of neuropathology and experimental neurology

    Key finding: OB Aβ and tau pathology significantly predicted a Thal phase greater than 3, a Braak NF stage greater than 4, and an MMSE score lower than 24.

    Full summary, score breakdown and related studies → Original source

  15. 2022-07-19

    The relationship between plasma biomarkers and amyloid PET in dementia with Lewy bodies

    ✓ Peer-reviewed Biomarkers Parkinsonism & related disorders

    Key finding: All four plasma markers significantly correlated with 18F-florbetapir SUVR (|β| = 0.40-0.49; p < .05). +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2022-07-19

    Modifiable risk factors for incident dementia and cognitive impairment: An umbrella review of evidence

    ✓ Peer-reviewed Risk factors Journal of affective disorders

    Key finding: Modifiable risk factors identified in this study, especially those with high-level evidence, should be considered in dementia prevention. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2022-07-19

    Amyloid-beta misfolding and GFAP predict risk of clinical Alzheimer's disease diagnosis within 17 years

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Aβ misfolding and GFAP showed a strong ability to predict clinical AD risk and may be important early AD risk markers.

    Full summary, score breakdown and related studies → Original source

  18. 2022-07-19

    Digital Cognitive Biomarker for Mild Cognitive Impairments and Dementia: A Systematic Review

    ✓ Peer-reviewed Digital health tools Journal of clinical medicine

    Key finding: The dementia population is increasing as the world's population is growing older.

    Full summary, score breakdown and related studies → Original source

  19. 2022-07-18

    Effects of cerebral amyloid angiopathy on the brain vasculome

    ✓ Peer-reviewed Vascular contributions Aging cell

    Key finding: Microarray profiling of these endothelial transcriptomes demonstrated that accumulation of vascular Aβ in the aging APPswe/PSEN1dE9 mouse is associated with impaired endothelial expression of neurotransmitter receptors and calcium signaling transductors, while the genes involved in cell cycle and inflammation were upregulated. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2022-07-18

    Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice

    ✓ Peer-reviewed Treatments Molecular brain

    Key finding: We found that intraperitoneal injection of donepezil (1 mg/kg, i.p.) exhibited significant reductions in Aβ plaque number in the cortex and hippocampal DG region. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2022-07-18

    Investigating the Genetic Characteristics of Hippocampal Volume and Plasma β-Amyloid in a Chinese Community-Dwelling Population

    ✓ Peer-reviewed Genetics Neurology

    Key finding: A total of 1,261 participants from a Chinese community cohort were included and we identified 1 gene, PTPRT, for HV, with the top significant SNPs by whole genome-wide association study (GWAS). rs6030076 (p = 5.48 × 10-8, β = -0.092, SE 0.017) from WES and rs6030088 (p = 8.24 × 10-9, β = -105.22, SE 18.09) from SNP array data were both located in this gene. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2022-07-17

    Findings of 18 F‐PI‐2620 tau PET imaging in patients with Alzheimer’s disease and healthy controls in relation to the plasma P‐tau181 levels in a Japanese sample

    ✓ Peer-reviewed Biomarkers Neuropsychopharmacology Reports

    Key finding: The uptake of 18 F‐PI‐2620 was distinctly increased in the AD group across all the ROIs. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2022-07-14

    Metformin use and brain atrophy in nondemented elderly individuals with diabetes

    ✓ Peer-reviewed Drug development Experimental gerontology

    Key finding: Among 157 subjects with a mean age of 71.8 (±7.7) included in this study, 76 individuals were stratified as metformin users. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2022-07-14

    Systematic Review on Saliva Biomarkers in Patients Diagnosed with Morbus Alzheimer and Morbus Parkinson

    ✓ Peer-reviewed Tau biomarkers Biomedicines

    Key finding: In Parkinson's disease (PD), Lewy bodies, i.e., intraneuronal protein deposits comprising the protein α-synuclein, are a typical disease feature. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2022-07-14

    Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

    ✓ Peer-reviewed TREM2 and immune genetics Hepatology (Baltimore, Md.)

    Key finding: Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →