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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,426–8,450 of 27,380 studies, newest first · page 338 of 1096.

October 2022 1

  1. 2022-10-01

    Association of Daily Step Count and Intensity With Incident Dementia in 78 430 Adults Living in the UK

    ✓ Peer-reviewed Prevention and risk JAMA Neurology

    Key finding: In this cohort study, a higher number of steps was associated with lower risk of all-cause dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

September 2022 24

  1. 2022-09-30

    The role of cognitive and brain reserve in late-life depressive events: The Rotterdam Study

    ✓ Peer-reviewed Risk factors Journal of affective disorders

    Key finding: Higher cognitive (HR: 0.91/SD, 95%CI: 0.84; 1.00) and brain reserve (HR: 0.88/SD, 95%CI: 0.77; 1.00) were associated with a lower risk of a depressive event after adjustment for baseline depressive symptoms. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-09-30

    A Pathophysiological Intersection of Diabetes and Alzheimer's Disease

    ✓ Peer-reviewed Risk factors International journal of molecular sciences

    Key finding: Diabetes is among the most prevalent diseases of the modern world and is strongly linked to an increased risk of numerous neurodegenerative disorders, although the exact pathophysiological mechanisms are not clear yet. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2022-09-30

    Locus coeruleus catecholamines link neuroticism and vulnerability to tau pathology in aging

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: Lower LC catecholamine synthesis capacity was associated with higher neuroticism, more depressive symptoms as measured by the Geriatric Depression Scale, and higher amygdala tau-PET binding. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2022-09-30

    Elevation of plasma phosphorylated tau181 during neurological illnesses affecting consciousness and kidney dysfunction

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Among participants enrolled, the median (interquartile range) age was 57 (28.5-75) years and 5.8% had AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-09-30

    Validation of the Remote Automated ki:e Speech Biomarker for Cognition in Mild Cognitive Impairment: Verification and Validation following DiME V3 Framework

    ✓ Peer-reviewed Cognitive tests and assessment Digital biomarkers

    Key finding: Our results suggest that the ki:e SB-C is an objective, scalable, and reliable indicator of cognitive decline, fit for purpose as a remote assessment in clinical early dementia trials. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-09-30

    Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities

    ✓ Peer-reviewed Long-term cohort studies Neurobiology of disease

    Key finding: However, brains from individuals clinically diagnosed with "AD-type" (amnestic) dementia usually harbor heterogeneous neuropathologies in addition to, or other than, ADNC. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2022-09-30

    Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Acta neuropathologica communications

    Key finding: Regulatory T cells (Tregs) play a neuroprotective role by suppressing microglia and macrophage-mediated inflammation and modulating adaptive immune reactions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2022-09-30

    A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study

    ✓ Peer-reviewed Caregiving The Lancet. Digital health

    Key finding: We tested the trained model using five other studies, three of which used PET as a biomarker of significant amyloid β burden (testing the deep learning model between amyloid β positive vs amyloid β negative). +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2022-09-29

    High-clearance anti-amyloid immunotherapies in Alzheimer's disease. Part 1: Meta-analysis and review of efficacy and safety data, and medico-economical aspects

    ✓ Peer-reviewed Treatments Revue neurologique

    Key finding: In 2021, aducanumab, an immunotherapy targeting amyloid-β, was approved for Alzheimer's disease (AD) by the US Food and Drug Administration thanks to positive results on a putative biological surrogate marker. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2022-09-29

    Effect of a Digital Literacy Program on Older Adults' Digital Social Behavior: A Quasi-Experimental Study

    ✓ Peer-reviewed Digital health tools International journal of environmental research and public health

    Key finding: The experimental group showed a significant increase in smartphone usage and video recording capacity than the control group. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2022-09-29

    Impact of Amyloid and Tau PET on Changes in Diagnosis and Patient Management

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: The combination of amyloid and tau PETs was associated with changes in management and diagnosis of MCI and dementia, and the second-generation tau PET has a strong impact on the changes in diagnosis and management in memory clinics. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2022-09-28

    Olfactory loss is a predisposing factor for depression, while olfactory enrichment is an effective treatment for depression

    ✓ Peer-reviewed Risk factors Frontiers in neuroscience

    Key finding: The loss of olfactory stimulation correlates well with at least 68 widely differing neurological disorders, including depression, and we raise the possibility that this relationship may be causal. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2022-09-28

    Sensory Loss and Risk of Dementia

    ✓ Peer-reviewed Risk factors The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry

    Key finding: More generally, sensory impairment could be related to factors associated with resilience against dementia.

    Full summary, score breakdown and related studies → Original source

  14. 2022-09-28

    Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer's disease? An updated meta-analysis

    ✓ Peer-reviewed Prevention trials Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    Key finding: In AD a clinical recommendation can be made for NEURO-AD TM system and for high-frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC) as probably effective protocols (B-level of evidence) and for anodal tDCS over the left DLPFC as a possibly effective. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2022-09-26

    Early life stress impairs synaptic pruning in the developing hippocampus

    ✓ Peer-reviewed TREM2 and immune genetics Brain, behavior, and immunity

    Key finding: According to the 'cumulative model' the number of early adversities can be summed up to determine the risk for developing psychopathology later in life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2022-09-26

    Potential association between frailty and pTau in community-dwelling older adults

    ✓ Peer-reviewed Biomarkers BMC geriatrics

    Key finding: Among the 12 biomarkers, only pTau was higher in frail individuals than in their not-frail peers (471.3 ± 58.1 pg/mL vs. 451.9 ± 61.1 pg/mL, p = 0.022). +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2022-09-24

    Prevalence of Comorbid Dementia in Late-life Depression and Bipolar Disorder: A Retrospective Inpatient Study

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease reports

    Key finding: A total of 66 patients with MDD (n = 50) and BD (n = 16) were analyzed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2022-09-24

    APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases

    ✓ Peer-reviewed Genetics Molecular neurodegeneration

    Key finding: Starting from the evolution of apoE to how APOE's single-nucleotide polymorphisms affect its structure, function, and involvement during health and disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2022-09-24

    Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Creatinine and BMI are related to certain plasma biomarkers levels, but they do not have clinically relevant confounding effects for the vast majority of individuals.

    Full summary, score breakdown and related studies → Original source

  20. 2022-09-24

    DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

    ✓ Peer-reviewed Inflammation and the immune system Nature communications

    Key finding: We meta-analyzed our results with those from previous studies of DNA methylation in AD cortex (total n = 2013 donors), identifying 334 cortical differentially methylated positions (DMPs) associated with AD pathology including methylomic variation at loci not previously implicated in dementia.

    Full summary, score breakdown and related studies → Original source

  21. 2022-09-24

    Prevalence and Factors Associated with Pain in Nursing Home Residents: A Systematic Review of the Literature

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: This review highlights the complexities of pain in NH residents and has implications for both clinical practice and future research. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2022-09-24

    Statins Use in Alzheimer Disease: Bane or Boon from Frantic Search and Narrative Review

    ✓ Peer-reviewed Disease mechanisms Brain sciences

    Key finding: Extensive and prolonged use of statins may affect cognitive functions in healthy subjects and dementia patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2022-09-24

    A systematic review of the cost-effectiveness of community and population interventions to reduce the modifiable risk factors for dementia

    ✓ Peer-reviewed Risk factors Maturitas

    Key finding: Evidence suggests that tackling modifiable lifecourse risk factors could prevent or delay a significant proportion of cases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2022-09-24

    Associations of grip strength, walking pace, and the risk of incident dementia: A prospective cohort study of 340212 participants

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Grip strength and walking pace have been linked to cognitive dysfunction. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →