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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 10,926–10,950 of 27,380 studies, newest first · page 438 of 1096.

November 2020 25

  1. 2020-11-27

    Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Science advances

    Key finding: Cross-sectionally, we found connectivity of tau epicenters (i.e., regions with earliest tau) to predict estimated tau spreading sequences. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-11-27

    Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: We showed that the sinergistic combination of the histone deacetilase inhibitor MS-275 with the sirtuin 1 activator resveratrol, at very low doses, restores normal RelA acetylation and elicit neuroprotection in mice subjected to transient middle cerebral artery occlusion (tMCAO) and primary cortical neurons exposed to oxygen-glucose-deprivation (OGD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2020-11-26

    Later-Onset Hypertension Is Associated With Higher Risk of Dementia in Mild Cognitive Impairment

    ✓ Peer-reviewed Risk factors Frontiers in neurology

    Key finding: However, the cox proportional hazard showed that older age was the only risk factor for MCIp (HR = 0.618, p = 0.000). +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2020-11-26

    Convolutional neural network to identify symptomatic Alzheimer's disease using multimodal retinal imaging

    ✓ Peer-reviewed Brain scans and imaging The British journal of ophthalmology

    Key finding: 284 eyes of 159 subjects (222 eyes from 123 cognitively healthy subjects and 62 eyes from 36 subjects with AD) were used to develop the model. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2020-11-26

    Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

    ✓ Peer-reviewed Inflammation and the immune system Translational neurodegeneration

    Key finding: Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.

    Full summary, score breakdown and related studies → Original source

  6. 2020-11-26

    Combined physical and cognitive training for older adults with and without cognitive impairment: A systematic review and network meta-analysis of randomized controlled trials

    ✓ Peer-reviewed Prevention trials Ageing research reviews

    Key finding: In cognitively healthy older adults and mild cognitive impairment, the effect of any combined intervention relative to control was small and statistically significant for overall cognitive (k = 41, Hedges' g = 0.22, 95 % CI 0.14 to 0.30) and physical function (k = 32, g = 0.25, 95 % CI 0.13 to 0.37). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-11-26

    Selecting the most important self-assessed features for predicting conversion to mild cognitive impairment with random forest and permutation-based methods

    ✓ Peer-reviewed Digital health tools Scientific reports

    Key finding: Mild cognitive impairment (MCI) is an intermediary stage between the expected decline of normal aging and the pathological decline associated with dementia.

    Full summary, score breakdown and related studies → Original source

  8. 2020-11-25

    Statin therapy and risk of Alzheimer's and age-related neurodegenerative diseases

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia (New York, N. Y.)

    Key finding: Benefits and risks of statins relative to neurological outcomes should be considered when prescribed for at-risk NDD populations. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2020-11-25

    The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology

    ✓ Peer-reviewed Disease mechanisms Pharmacological research

    Key finding: The microbiota, the gut, and the brain form an association, 'the microbiota-gut-brain axis,' and synchronize the gut with the central nervous system and modify the behavior and brain immune homeostasis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-11-25

    A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population

    ✓ Peer-reviewed Caregiving The Science of the total environment

    Key finding: Cognitive decline and dementia incidence have also been consistently associated with exposure to air pollution.

    Full summary, score breakdown and related studies → Original source

  11. 2020-11-24

    A case of comorbidities highlighting cerebral stroke, vision impairment, and dementia

    ✓ Peer-reviewed Risk factors SAGE open medical case reports

    Key finding: This case report is of a two-time stroke survivor with significant health comorbidities. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2020-11-24

    Computerised cognitive training in Parkinson's disease: a protocol for a systematic review and updated meta-analysis

    ✓ Peer-reviewed Cognitive tests and assessment BMJ open

    Key finding: Cognitive impairment is recognised as an important non-motor symptom in Parkinson's disease (PD) and there is a need for evidence-based non-pharmacological interventions that may prevent or slow cognitive decline in this patient group.

    Full summary, score breakdown and related studies → Original source

  13. 2020-11-24

    Digital Gaming Interventions in Psychiatry: Evidence, Applications and Challenges

    ✓ Peer-reviewed Prevention trials Psychiatry research

    Key finding: Research shows their utility in ADHD, autistic spectrum disorders, eating disorders, post-traumatic stress, impulse control disorders, depression, schizophrenia, dementia, and even healthy aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-11-24

    Integrative Brain Transcriptome Analysis Links Complement Component 4 andHSPA2to theAPOEε2 Protective Effect in Alzheimer Disease

    ✓ Peer-reviewed Tau biomarkers Molecular psychiatry

    Key finding: We analyzed gene expression data derived from autopsied brains donated by 982 individuals including 135 APOE ε 2/ε 3 carriers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-11-23

    Cerebrospinal fluid α-synuclein predicts neurodegeneration and clinical progression in non-demented elders

    ✓ Peer-reviewed Tau biomarkers Translational neurodegeneration

    Key finding: The CSF α-synuclein levels correlated with AD-specific biomarkers, CSF total tau and phosphorylated tau levels, in 651 Chinese Han participants (training set). +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-11-23

    Renal function is associated with blood neurofilament light chain level in older adults

    ✓ Peer-reviewed Biomarkers Scientific reports

    Key finding: In each group, levels of blood NfL and serum creatinine significantly correlated (coefficient r = 0.50, 0.56). +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2020-11-23

    Distinct Brain Functional Impairment Patterns Between Suspected Non-Alzheimer Disease Pathophysiology and Alzheimer's Disease: A Study Combining Static and Dynamic Functional Magnetic Resonance Imaging

    ✓ Peer-reviewed Tau biomarkers Frontiers in aging neuroscience

    Key finding: It accounts for a quarter of the elderly population and is associated with cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2020-11-23

    Clinician-Focused Overview and Developments in Polysomnography

    ✓ Peer-reviewed Digital health tools Current sleep medicine reports

    Key finding: Polysomnography (PSG) represents a fundamental diagnostic tool used in the evaluation of sleep disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020-11-23

    A comparison of machine learning methods for survival analysis of high-dimensional clinical data for dementia prediction

    ✓ Peer-reviewed Digital health tools Scientific reports

    Key finding: Machine learning models that can predict the time until a patient develops dementia are important tools in helping understand dementia risks and can give more accurate results than traditional statistical methods when modelling high-dimensional, heterogeneous, clinical data.

    Full summary, score breakdown and related studies → Original source

  20. 2020-11-23

    Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue

    ✓ Peer-reviewed Biomarkers Molecular neurodegeneration

    Key finding: This study provides new insights into the regional binding distribution of a first-generation and a second-generation Tau tracer in limbic and neocortical regions in adults with DS, as well as regional differences in Tau binding in adult with DS vs. those with AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2020-11-22

    Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

    ✓ Peer-reviewed Genetics Translational psychiatry

    Key finding: Utilizing the results from independent case-control AD GWAS to construct polygenic risk scores (PRS) revealed that AD risk variants only explain a small fraction of CSF biomarker variability. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2020-11-21

    Metabolomics analysis of microbiota-gut-brain axis in neurodegenerative and psychiatric diseases

    ✓ Peer-reviewed Disease mechanisms Journal of pharmaceutical and biomedical analysis

    Key finding: Alterations in the microbiome metabolism affect the body homeostasis and they have been associated with the development of different human neurodegenerative and neuropsychiatric disorders, such as Alzheimer's disease, autism spectrum disorder, bipolar disorder, depression, Huntington's disease, Parkinson's disease, posttraumatic stress disorder and schizophrenia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2020-11-20

    Sex Differences in the Gut-Brain Axis: Implications for Mental Health

    ✓ Peer-reviewed Disease mechanisms Current psychiatry reports

    Key finding: The purpose of this article is to highlight how sex differences in the gut-brain axis may contribute to the discrepancies in incidence of neurodevelopmental, psychiatric, and neurodegenerative disorders between females and males. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-11-20

    Cognitively Impaired Older Persons' and Caregivers' Perspectives on Dementia-Specific Advance Care Planning

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Even among patients with early cognitive impairment seen in specialty clinics and their caregivers, most were unaware of the decisions they could face, and there were many barriers to planning for these decisions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2020-11-20

    Dementia in Latin America: Paving the way toward a regional action plan

    ✓ Peer-reviewed Disparities Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →