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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,151–8,175 of 27,380 studies, newest first · page 327 of 1096.

December 2022 25

  1. 2022-12-26

    Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Carriers had higher plasma p-tau217 levels than non-carriers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-12-26

    The Differential Diagnosis and Treatment of Mild Cognitive Impairment and Alzheimer Disease

    ✓ Peer-reviewed Drug development The Journal of clinical psychiatry

    Key finding: That said, successfully navigating the associated differential diagnosis in AD is essential, as various causes of cognitive impairment require different treatment strategies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2022-12-25

    Analysis of Cerebral Small Vessel Changes in AD Model Mice

    ✓ Peer-reviewed Vascular contributions Biomedicines

    Key finding: Compared to wild-type (WT), vessel density was increased at 2 months but decreased at 9 months in J20 mice, claudin-5 levels were decreased, and vascular endothelial growth factor (VEGF) levels were increased in the cortex and hippocampus of J20 mice brain at all time points. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2022-12-23

    Cognitive and brain reserve predict decline in adverse driving behaviors among cognitively normal older adults

    ✓ Peer-reviewed Risk factors Frontiers in psychology

    Key finding: These changes indicate that those with lower BR and CR are more likely to reduce their driving exposure and limit trips as they age and may be more likely to avoid highways where speeding and aggressive maneuvers frequently occur.

    Full summary, score breakdown and related studies → Original source

  5. 2022-12-23

    Inflammation context in Alzheimer's disease, a relationship intricate to define

    ✓ Peer-reviewed Inflammation and the immune system Biological research

    Key finding: Importantly, Aβ and tau species are able to activate astrocytes and microglia, which release several proinflammatory cytokines, such as tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β), together with reactive oxygen (ROS) and nitrogen species (RNS), triggering neuroinflammation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-12-23

    TREM2 dependent and independent functions of microglia in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: In this review, we aim to summarize the genetic and functional discoveries that have advanced our understanding of microglia reactivity to AD pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2022-12-23

    Promotors and barriers to the implementation and adoption of assistive technology and telecare for people with dementia and their caregivers: a systematic review of the literature

    ✓ Peer-reviewed Digital health tools BMC health services research

    Key finding: The most crucial elements for the adoption of ATT in the future will be a focus on co-design, improved involvement of relevant stakeholders, and the adaptability (tailoring related to context) of ATT solutions over time (disease process). +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2022-12-22

    Insulin resistance in Alzheimer's disease: The genetics and metabolomics links

    ✓ Peer-reviewed Risk factors Clinica chimica acta; international journal of clinical chemistry

    Key finding: Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic burden worldwide. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2022-12-22

    Memory-driven eye movements prospectively predict dementia in people at risk of Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Baseline data predicted that 36 patients with MCI would progress to the AD clinical syndrome (ADS Progressing). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2022-12-22

    Donanemab for Alzheimer's Disease: A Systematic Review of Clinical Trials

    ✓ Peer-reviewed Treatments Healthcare (Basel, Switzerland)

    Key finding: Adult patients with Alzheimer’s disease being intervened with Donanemab compared to placebo or standard of care in the clinical trial setting were included. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2022-12-22

    Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases

    ✓ Peer-reviewed Prevention trials Nutrients

    Key finding: Certain diets, such as the Mediterranean diet, may play a significant role in healthy aging by preventing the onset of certain diseases and by improving the aging process itself. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2022-12-22

    Predicting dementia from spontaneous speech using large language models

    ✓ Peer-reviewed Digital health tools PLOS digital health

    Key finding: Together, our results suggest that GPT-3 based text embedding is a viable approach for AD assessment directly from speech and has the potential to improve early diagnosis of dementia.

    Full summary, score breakdown and related studies → Original source

  13. 2022-12-22

    African ancestry GWAS of dementia in a large military cohort identifies significant risk loci

    ✓ Peer-reviewed Disparities Molecular psychiatry

    Key finding: These two GWASs were meta-analyzed, and then subsequently compared and meta-analyzed with the results from a previous AFR AD GWAS from the Alzheimer's Disease Genetics Consortium (ADGC). +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2022-12-21

    Incretin-based therapy of metabolic disease

    ✓ Peer-reviewed Drug development Danish medical journal

    Key finding: Recent studies show that incretin hormone analogues effectively control blood glucose while producing major weight losses and reducing the risk of all-cause mortality, myocardial infarction, stroke and kidney function impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2022-12-21

    A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants

    ✓ Peer-reviewed Genetics International journal of molecular sciences

    Key finding: The analysis identified a locus in CDKN2B-AS1 (rs6475609, p = 7.13 × 10-8) that almost reached genome-wide significance and four additional loci that were suggestively significant. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2022-12-21

    Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Lecanemab treatment resulted in significant reduction in amyloid plaques and a slowing of clinical decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2022-12-21

    MIND Dietary Pattern and Its Association with Cognition and Incident Dementia in the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Nutrients

    Key finding: We measured adherence to MIND and its association with cognitive health in the UK Biobank (UKB). +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2022-12-21

    Multi-organ imaging demonstrates the heart-brain-liver axis in UK Biobank participants

    ✓ Peer-reviewed Long-term cohort studies Nature communications

    Key finding: However, most imaging research either describes a single organ system or draws on clinical cohorts with small sample sizes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2022-12-21

    Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis

    ✓ Peer-reviewed Prevention and risk European Heart Journal

    Key finding: The first single-stage individual patient data meta-analysis from randomized double-blind placebo-controlled clinical trials provides evidence to support benefits of antihypertensive treatment in late-mid and later life to lower the risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2022-12-20

    Automatic lesion detection and segmentation in 18F-flutemetamol positron emission tomography images using deep learning

    ✓ Peer-reviewed Brain scans and imaging Biomedical engineering online

    Key finding: The following intersection over union values were obtained for the various slices in the verification dataset: frontal lobe axial/sagittal: 0.733/0.804; posterior cingulate cortex and precuneus coronal/sagittal: 0.661/0.726; lateral temporal lobe axial/coronal: 0.864/0.892; parietal lobe axial/coronal: 0.542/0.759; and striatum axial/sagittal: 0.679/0.752. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2022-12-20

    Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans

    ✓ Peer-reviewed Genetics Alzheimer's & Dementia

    Key finding: Our ancestry-aware regression approach showed that AA individuals have a lower risk of AD if they inherited African ancestry admixture block at the 17p13.2 locus. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2022-12-19

    '24/7' Caregiving: A Qualitative Analysis of an Emerging Phenomenon of Interest in Caregiving

    ✓ Peer-reviewed Caregiving International journal of environmental research and public health

    Key finding: The findings revealed three themes that defined the shared experiences of '24/7' caregivers: (1) A World Overturned, which refers to the increase in caregiving intensity and burden due to the pandemic; (2) Burning on Both Ends, which refers to the impossible balance between caregiving and their personal lives; and (3) At Wits' End, which refers to an overwhelming sense of hopelessness and helplessness over their caregiving situation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2022-12-19

    A framework for concepts of reserve and resilience in aging

    ✓ Peer-reviewed Risk factors Neurobiology of aging

    Key finding: The use of a common vocabulary and operational definitions will facilitate even greater progress in understanding the factors that are associated with successful aging.

    Full summary, score breakdown and related studies → Original source

  24. 2022-12-17

    Association Between Alcohol Use Disorders and Dementia in 262,703 Dementia-free Finnish Adults: Is Cardiovascular Disease a Mediator?

    ✓ Peer-reviewed Health systems and care delivery The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: AUD was associated with a substantial increase in the risk of early-onset dementia in both men (hazard ratio: 5.67, 95% confidence interval: 4.37-7.46) and women (6.13, 4.20-8.94) after adjustments for confounding; but the elevated risk for late-onset dementia was smaller (men: 2.01, 1.80-2.25; women: 2.03, 1.71-2.40). +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2022-12-17

    Medicare Hospice Policy Changes and Beneficiaries' Rate of Live Discharge and Length-of-Stay

    ✓ Peer-reviewed Health systems and care delivery Journal of pain and symptom management

    Key finding: We compared prepolicies trends and postpolicies trends overall, within Alzheimer's disease and related dementias (ADRD) patients, within lung cancer patients, and stratified by hospice ownership (for-profit vs. nonprofit/government-owned). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →