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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,651–14,675 of 27,380 studies, newest first · page 587 of 1096.

October 2017 25

  1. 2017-10-20

    Improving Care Through Public Policy

    ✓ Peer-reviewed Risk factors The Gerontologist

    Key finding: As has been noted, Alzheimer’s and related dementias are underdiagnosed and when diagnoses are made, they are too often undisclosed by clinicians: studies suggest that fewer than half of individuals report being told of their diagnoses (Alzheimer’s Association, 2015). +4 more findings

  2. 2017-10-20

    Cognitive Frailty in China: Results from China Comprehensive Geriatric Assessment Study

    ✓ Peer-reviewed Disparities Frontiers in medicine

    Key finding: Our results provide the first empirical evidence of CF in China. +4 more findings

  3. 2017-10-19

    Neural basis of major depressive disorder: Beyond monoamine hypothesis

    ✓ Peer-reviewed Hippocampus size on brain scans Psychiatry and clinical neurosciences

    Key finding: Past studies have revealed that the volume of the hippocampus is decreased in patients with MDD, which is likely caused by the failure of the hypothalamic-pituitary-adrenal axis and following elevation of glucocorticoids.

  4. 2017-10-19

    Gut microbiome alterations in Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Scientific reports

    Key finding: Recent studies in rodents suggest that alterations in the gut microbiome may contribute to amyloid deposition, yet the microbial communities associated with AD have not been characterized in humans. +3 more findings

  5. 2017-10-19

    Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The FINGER intervention was beneficial regardless of participants' characteristics and can thus be implemented in a large elderly population at increased risk for dementia. +2 more findings

  6. 2017-10-18

    Triggering Receptor Expressed on Myeloid Cells 2 Overexpression Inhibits Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Microglia

    ✓ Peer-reviewed TREM2 and immune genetics Mediators of inflammation

    Key finding: We showed that lipopolysaccharide (LPS) stimulation significantly increases proinflammatory cytokines and suppressed TREM2 in microglia. +2 more findings

  7. 2017-10-18

    Oxidative stress and the amyloid beta peptide in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Redox biology

    Key finding: Histopathological hallmarks of AD are intracellular neurofibrillary tangles and extracellular formation of senile plaques composed of the amyloid-beta peptide (Aβ) in aggregated form along with metal-ions such as copper, iron or zinc. +4 more findings

  8. 2017-10-18

    Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Scientific reports

    Key finding: It has previously been shown that the consumption of probiotics may have beneficial effects not only on peripheral tissues but also on the central nervous system and behavior via the microbiota-gut-brain axis, raising the possibility that treatment with probiotics could be an effective therapeutic strategy for managing neurodegenerative disorders. +4 more findings

  9. 2017-10-18

    In vivo staging of regional amyloid deposition

    ✓ Peer-reviewed How common it is Neurology

    Key finding: The highly consistent regional hierarchy of PET-evidenced amyloid deposition across participants resembles neuropathologic observations and suggests a predictable regional sequence that may be used to stage an individual's progress of amyloid pathology in vivo. +1 more finding

  10. 2017-10-17

    Microbiota-Brain-Gut Axis and Neurodegenerative Diseases

    ✓ Peer-reviewed Disease mechanisms Current neurology and neuroscience reports

    Key finding: The purposes of this review were as follows: first, to provide an overview of the gut microbiota and its interactions with the gut and the central nervous system (the microbiota-gut-brain axis) in health, second, to review the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson's disease, and, finally, to assess the potential for microbiota-targeted therapies. +4 more findings

  11. 2017-10-17

    Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae

    ✓ Peer-reviewed Drug development Nature communications

    Key finding: Traumatic brain injury (TBI) is characterized by acute neurological dysfunction and associated with the development of chronic traumatic encephalopathy (CTE) and Alzheimer's disease. +3 more findings

  12. 2017-10-17

    Can we predict your future? Using scores to predict length of stay and discharge destination

    ✓ Peer-reviewed Health systems and care delivery International Journal of Integrated Care

    Key finding: 120 patients were included in the audit with a confirmed stroke on CTB/MRI. +4 more findings

  13. 2017-10-16

    The potential of solanezumab and gantenerumab to prevent Alzheimer's disease in people with inherited mutations that cause its early onset

    ✓ Peer-reviewed Treatments Expert opinion on biological therapy

    Key finding: The recent failure of several clinical trials on anti-β-amyloid (Aβ) drugs in Alzheimer's disease (AD) suggested earlier intervention in the disease course. +4 more findings

  14. 2017-10-16

    Considerations and code for partial volume correcting [ 18 F]-AV-1451 tau PET data

    ✓ Peer-reviewed Brain scans and imaging Data in brief

    Key finding: PET signal unlikely to be associated with tau also occurs in skull, meninges and soft tissue (see e.g. [4]).

  15. 2017-10-16

    Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Brain research

    Key finding: Previous studies have shown that the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) that have anti-diabetic properties show very promising effects in animal models of AD. +2 more findings

  16. 2017-10-16

    Triggering receptor expressed on myeloid cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice

    ✓ Peer-reviewed TREM2 and immune genetics Brain, behavior, and immunity

    Key finding: Patients treated with chemotherapy often report pain and paresthesias in a "glove-and-stocking" distribution. +3 more findings

  17. 2017-10-16

    TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurodegeneration

    Key finding: Here we report that TREM2 deficiency leads to accelerated and exacerbated hyperphosphorylation and aggregation of tau in a humanized mouse model of tauopathy. +3 more findings

  18. 2017-10-16

    Unravelling positive aspects of caregiving in dementia: An integrative review of research literature

    ✓ Peer-reviewed Caregiving International journal of nursing studies

    Key finding: The findings of this review provide insight into catalysing the paradigm shift from 'reducing stress' to 'optimising positive experience' in developing caregiving support services for dementia, and may guide future empirical study to explain this unique dimension of caregiving experience. +1 more finding

  19. 2017-10-14

    Gut microbiota changes in the extreme decades of human life: a focus on centenarians

    ✓ Peer-reviewed Disease mechanisms Cellular and molecular life sciences : CMLS

    Key finding: We likewise address the role of GM in neurodegenerative diseases such as Parkinson's and Alzheimer's, and its possible therapeutic use, taking advantage of the fact that centenarians are characterized by an extreme (healthy) phenotype versus patients suffering from age-related pathologies.

  20. 2017-10-14

    Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging

    ✓ Peer-reviewed TREM2 and immune genetics Biological psychiatry

    Key finding: However, the precise mechanisms by which microglia alter the course of AD neuropathology remain poorly understood. +3 more findings

  21. 2017-10-13

    Alzheimer’s Disease Biomarkers and Future Decline in Cognitive Normal Older Adults

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer s Disease

    Key finding: 14% participants increased their global Clinical Dementia Rating (CDR) score from 0 to 0.5 during follow-up. +4 more findings

  22. 2017-10-12

    Readily Identifiable Risk Factors of Nursing Home Residents' Oral Hygiene: Dementia, Hospice, and Length of Stay

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: The findings identify resident subgroups at especially high risk of poor oral health who can be targeted in quality improvement efforts related to oral hygiene; they also indicate need to improve the accuracy of how MDS items are completed. +2 more findings

  23. 2017-10-12

    End-of-life care: A qualitative study comparing the views of people with dementia and family carers

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: Seven areas were identified as important to end-of-life care for people with dementia and/or family carers.

  24. 2017-10-12

    Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Free radical biology & medicine

    Key finding: We conclude by pointing to the need for additional studies to explore the biology of signaling endosomes in normal neurons and to elucidate their role in the pathogenesis of neurodegeneration.

  25. 2017-10-11

    Building IoT Services for Aging in Place Using Standard-Based IoT Platforms and Heterogeneous IoT Products

    ✓ Peer-reviewed Cognitive tests and assessment Sensors

    Key finding: Accordingly, seniors' ability to live independently and comfortably in their current home for as long as possible has been crucial to reduce the societal cost for caregiving and thus give family members peace of mind, called 'aging in place' (AIP). +4 more findings

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