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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 8,226–8,250 of 27,380 studies, newest first · page 330 of 1096.

December 2022 17

  1. 2022-12-01

    Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial

    ✓ Peer-reviewed Hippocampus size on brain scans JAMA

    Key finding: Among older adults with subjective cognitive concerns, mindfulness training, exercise, or both did not result in significant differences in improvement in episodic memory or executive function at 6 months. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-12-01

    Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring

    ✓ Peer-reviewed Tau biomarkers Nature Medicine

    Blood biomarkers indicative of Alzheimer's disease (AD) pathology are altered in both preclinical and symptomatic stages of the disease.

    Full summary, score breakdown and related studies → Original source

  3. 2022-12-01

    How to create value with unobtrusive monitoring technology in home-based dementia care: a multimethod study among key stakeholders

    ✓ Peer-reviewed Health systems and care delivery BMC geriatrics

    Key finding: The overall design-oriented need referred to clear situation classifications including urgent care (fall- and wandering detection), non-urgent care (deviations in eating, drinking, sleeping), and future care (risk predictions). +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2022-12-01

    Testing the Association Between Neighborhood Disadvantage and White Matter Hyperintensities

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: CVD risk has been associated with white matter lesions known as white matter hyperintensities (WMH) because they produce increased signal on fluid‐attenuated inversion recovery (FLAIR) MRI scans. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-12-01

    Air pollution and dementia using longitudinal electronic health record data from the Indian Health Service

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Our study suggests that exposure to O3 is associated with the higher risk of dementia in American Indians. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-12-01

    Neighborhood Deprivation and Mortality Risk among Medicare Beneficiaries with Alzheimer’s Disease and Related Dementia

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Our findings suggest neighborhood deprivation is an important risk factor of mortality among older adults with ADRD while accounting for individuals’ demographic and clinical characteristics. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2022-12-01

    Anger expression moderates the effects of neighborhood disadvantage on cognitive decline among African‐Americans in the Jackson Heart Study and Atherosclerosis Risk in Communities study

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia

    Key finding: Dispositional inward anger expression may increase susceptibility to the detrimental impacts of neighborhood disadvantage on cognitive health. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2022-12-01

    IMPROVING DEMENTIA CARE THROUGH DIGITAL CAREGIVER EMPOWERMENT: DURABLE CLAIMS‐BASED OUTCOMES DEMONSTRATED IN A PRAGMATIC REAL‐WORLD TRIAL

    ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

    Key finding: Empowering family caregivers of patients with ADOD in a personalized DCEP provides durable reductions in patient hospitalizations and medical costs. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2022-12-01

    Factors associated with high intensity of end‐of‐life care for decedents with dementia in a Medicare Advantage plan

    ✓ Peer-reviewed Health systems and care delivery Alzheimer s & Dementia

    Key finding: We found notable differences in socio‐demographic and clinical characteristics, and utilization patterns in the year prior to death between decedents with dementia who were hospitalized in the last 30 days of life vs. those who were not. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2022-12-01

    Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke

    ✓ Peer-reviewed Long-term cohort studies JAMA neurology

    Key finding: It is uncertain whether typical variants causing monogenic stroke are associated with cerebrovascular disease in the general population and why the phenotype of these variants varies so widely. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2022-12-01

    Plasma Aβ42/Aβ40 and p-tau181 Predict Long-Term Clinical Progression in a Cohort with Amnestic Mild Cognitive Impairment

    ✓ Peer-reviewed Tau biomarkers Clinical chemistry

    Key finding: Previous studies reported the value of blood-based biomarkers in predicting Alzheimer disease (AD) progression among individuals with different disease stages. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2022-12-01

    Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan

    ✓ Peer-reviewed Tau biomarkers Brain : a journal of neurology

    Key finding: By leveraging a large harmonized database from 8 biomarker studies with longitudinal data from 2609 participants in cognition, 873 in MRI biomarkers, 519 in PET PiB imaging and 475 in CSF biomarkers for a median follow-up of 5-6 years, we estimated the longitudinal trajectories of all major Alzheimer disease biomarkers as functions of baseline age that spanned from 18 to 103 years, located the baseline age window at which the longitudinal rates of change accelerated and further examined possible modifying effects of apolipoprotein E (APOE) genotype. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2022-12-01

    Estimating the Prevalence of Dementia and Mild Cognitive Impairment in the US: The 2016 Health and Retirement Study Harmonized Cognitive Assessment Protocol Project

    ✓ Peer-reviewed Getting a diagnosis JAMA neurology

    Key finding: The mean (SD) age of the study population sample (N = 3496) was 76.4 (7.6) years, and 2095 participants (60%) were female. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2022-12-01

    Dietary fish oil increases catalase activity in patients with probable Alzheimer's disease

    ✓ Peer-reviewed Treatments Nutricion hospitalaria

    Key finding: carbonyl groups in proteins and hydroperoxides in plasma have similar values in both treatment groups at the beginning of the study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2022-12-01

    Closing the Gap Between Observational Research and Randomized Controlled Trials for Prevention of Alzheimer Disease and Dementia

    ✓ Peer-reviewed Treatments Epidemiologic reviews

    Key finding: We conclude that the questions asked and answered by observational research can be made more relevant to clinical trial design and that better use of observational data may increase the likelihood of successful, or at least definitive, trials.

    Full summary, score breakdown and related studies → Original source

  16. 2022-12-01

    Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: Among cognitively normal participants with positive biomarkers, 34.4% developed cognitive impairment (Clinical Dementia Rating > 0) as compared to 8.4% of those with negative biomarkers. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2022-12-01

    Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: In TRAILBLAZER-ALZ, 272 participants (mean [SD] age, 75.2 [5.5] years; 145 [53.3%] female) were randomized. +4 more findings

    Full summary, score breakdown and related studies → Original source

November 2022 8

  1. 2022-11-30

    The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms

    ✓ Peer-reviewed Genetics Neurobiology of disease

    Key finding: To identify ancestry-concordant and -discordant expression profiles, we compared our results to those from two independent non-Hispanic White (NHW) samples (n = 731). +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2022-11-30

    β-Synuclein as a candidate blood biomarker for synaptic degeneration in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Synaptic degeneration is an early event closely associated with the course of Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2022-11-30

    PLD3 affects axonal spheroids and network defects in Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Nature

    Key finding: Spheroid growth was associated with an age-dependent accumulation of large endolysosomal vesicles and was mechanistically linked with Pld3-a potential Alzheimer's-disease-associated risk gene 1 that encodes a lysosomal protein 2,3 that is highly enriched in axonal spheroids.

    Full summary, score breakdown and related studies → Original source

  4. 2022-11-30

    Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Performance was assessed in comparison to clinical diagnosis (blinded to plasma results) and amyloid status (CSF/PET). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2022-11-29

    Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990–2019

    ✓ Peer-reviewed Prevention and risk Frontiers in Public Health

    Key finding: Globally, in 2019, there were nearly 10 million deaths and 349 million DALYs due to neurological disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2022-11-29

    Visual disorders and driving ability in persons with dementia: A mini review

    ✓ Peer-reviewed Risk factors Frontiers in human neuroscience

    Key finding: There is consistent evidence that dementia affects driving ability. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2022-11-29

    Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: The results from the gantenerumab phase 3 programs are expected by the end of 2022 and will add critical information to the collective knowledge on the search for effective AD treatments.

    Full summary, score breakdown and related studies → Original source

  8. 2022-11-29

    Methylation differences in Alzheimer's disease neuropathologic change in the aged human brain

    ✓ Peer-reviewed Genetics Acta neuropathologica communications

    Key finding: AD neuropathologic change (ADNC) is known to be associated with numerous DNA methylation changes in the human brain, but the oldest old (> 90 years) have so far been underrepresented in epigenetic studies of ADNC. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →