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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,701–7,725 of 27,380 studies, newest first · page 309 of 1096.

May 2023 22

  1. 2023-05-04

    Correlations between kynurenines in plasma and CSF, and their relation to markers of Alzheimer's disease pathology

    ✓ Peer-reviewed Tau biomarkers Brain, behavior, and immunity

    Key finding: Altered levels of kynurenines in blood and cerebrospinal fluid (CSF) have been reported in Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-05-03

    Plasma Biomarkers of Alzheimer's Disease: A Review of Available Assays, Recent Developments, and Implications for Clinical Practice

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease reports

    Key finding: Despite the significant variability, many studies have established in-house cut-off values for the most promising available biomarkers.

    Full summary, score breakdown and related studies → Original source

  3. 2023-05-03

    TREM2 promotes cholesterol uptake and foam cell formation in atherosclerosis

    ✓ Peer-reviewed TREM2 and immune genetics Cellular and molecular life sciences : CMLS

    Key finding: Previous studies found that the expression of triggering receptor expressed on myeloid cells 2 (TREM2), a transmembrane receptor of the immunoglobulin family, is increased in mouse atherosclerotic aortic plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-05-03

    Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Pericyte damage, reflected by CSF PDGFRβ, may be involved in age-related BBB disruption together with neuroinflammation, but is not related to Alzheimer-related pathologic changes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2023-05-02

    Educational attainment, structural brain reserve and Alzheimer's disease: a Mendelian randomization analysis

    ✓ Peer-reviewed Risk factors Brain : a journal of neurology

    Key finding: Higher educational attainment is observationally associated with lower risk of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023-05-02

    Plasma neurofilament light and brain volumetric outcomes among middle-aged urban adults

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: Elevated plasma neurofilament light chain (NfL) is associated with dementia though underlying mechanisms remain unknown. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-05 month only

    [Anti-Dementia Drugs (Anti-Alzheimer's Disease Drugs)]

    ✓ Peer-reviewed Treatments Brain and nerve = Shinkei kenkyu no shinpo

    Key finding: Alzheimer's disease (AD) treatment includes both non-pharmacological and pharmacological approaches. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-05-01

    Big tau aggregation disrupts microtubule tyrosination and causes myocardial diastolic dysfunction: from discovery to therapy

    ✓ Peer-reviewed Drug development European heart journal

    Key finding: A mouse model of tauopathy and human myocardial and brain tissue from patients with HF, AD, and controls was employed in this study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023-05 month only

    Ocular manifestations of central insulin resistance

    ✓ Peer-reviewed Brain scans and imaging Neural regeneration research

    Key finding: While neither blood glucose nor serum insulin level was significantly altered in the experimental or control group, we found that injection of S961 but not buffer solution significantly increased intraocular pressure at 14 and 24 days after first injection, along with reduced porosity and aquaporin 4 expression in the trabecular meshwork, and increased tumor necrosis factor α and aquaporin 4 expression in the ciliary body. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2023-05-01

    Sex differences in the progression of glucose metabolism dysfunction in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Experimental & molecular medicine

    Key finding: Transcriptome analysis of data from Cohorts 2 and 3 (European, n = 78; Singaporean, n = 18) revealed sex differences in AD-related alterations in brain metabolism. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-05-01

    Predicting amyloid PET and tau PET stages with plasma biomarkers

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: We used multinomial regression models to estimate discrimination [concordance (C) statistics] among three amyloid PET stages (low, intermediate, high), four tau PET stages (Braak 0, 1-2, 3-4, 5-6) and a combined amyloid and tau PET stage (none/low versus intermediate/high severity) using plasma biomarkers as predictors separately within unimpaired and impaired individuals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2023-05-01

    Six-Year Cognitive Trajectory in Older Adults Following Major Surgery and Delirium

    ✓ Peer-reviewed Clinical safety JAMA internal medicine

    Key finding: This cohort study found that delirium was associated with a 40% acceleration in the slope of cognitive decline out to 72 months following elective surgery. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-05-01

    Sex Differences in Alzheimer's Disease

    ✓ Peer-reviewed Prevention and risk Neurologic clinics

    Key finding: Medical, genetic, psychosocial, and behavioral factors, in addition to hormonal factors, can differentially affect the risk and progression of AD in women versus men.

    Full summary, score breakdown and related studies → Original source

  14. 2023-05-01

    Quality of plant-based diet and the risk of dementia and depression among middle-aged and older population

    ✓ Peer-reviewed Long-term cohort studies Age and ageing

    Key finding: However, not all plant-based foods are necessarily beneficial for dementia or depression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-05-01

    Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors

    ✓ Peer-reviewed Long-term cohort studies JAMA neurology

    Key finding: Epilepsy has been associated with cognitive impairment and potentially dementia in older individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2023-05-01

    Physical Frailty, Genetic Predisposition, and Incident Parkinson Disease

    ✓ Peer-reviewed Long-term cohort studies JAMA neurology

    Key finding: Cross-sectional evidence implicates high prevalent frailty in patients with Parkinson disease (PD), whereas the longitudinal association remains unknown. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2023-05-01

    Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease

    ✓ Peer-reviewed Long-term cohort studies JAMA network open

    Key finding: An estimated 40% of dementia is potentially preventable by modifying 12 risk factors throughout the life course. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-05-01

    Association of Age at Menopause and Hormone Therapy Use With Tau and β-Amyloid Positron Emission Tomography

    ✓ Peer-reviewed Brain scans and imaging JAMA neurology

    Key finding: In this study, females exhibited higher tau compared with age-matched males, particularly in the setting of elevated Aβ. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-05-01

    Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association

    ✓ Peer-reviewed Getting a diagnosis Stroke

    Key finding: PSCI is common after stroke, especially in the first year, and ranges from mild to severe.

    Full summary, score breakdown and related studies → Original source

  20. 2023-05-01

    Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Regions with Z -scores Results Patients with AD (n = 206) had a median of 12 outlier regions (out of a possible 148), with the highest proportion of outliers (47%) in the parahippocampal gyrus. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2023-05-01

    Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Of 386 participants, 199 (52%) were female, and the mean (SD) age was 68 (8) years. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-05-01

    Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Higher eGFR was associated with increased levels of plasma p-tau217, p-tau181, Tau212-221, and Tau181-190 in individuals with cognitive impairment (cohort 1: R range, -0.24 to -0.59; P Conclusions and relevance In this study, CKD was associated with increased plasma levels of soluble tau, but for p-tau217 the associations were considerably lower than the association with Aβ positivity. +3 more findings

    Full summary, score breakdown and related studies → Original source

April 2023 3

  1. 2023-04-30

    Sensory impairment and beta-amyloid deposition in the Baltimore longitudinal study of aging

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The combinations of hearing and proprioceptive impairment and hearing, vision, and proprioceptive impairment, were positively correlated with cDVR (β = 0.087 and p = 0.036, β = 0.110 and p = 0.018, respectively). +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-04-29

    Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator

    ✓ Peer-reviewed Down syndrome and Alzheimer's Annals of neurology

    Key finding: Our studies point to increased APP gene dose as a compromising retromer function in DS and suggest a causal role for Aβ42 and Aβ40. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2023-04-28

    Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate

    ✓ Peer-reviewed Genetics Angewandte Chemie (International ed. in English)

    Key finding: Glycan microarray and SPR assays revealed that all ApoE isoforms recognized 3-O-S. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →