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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,551–7,575 of 27,380 studies, newest first · page 303 of 1096.

July 2023 4

  1. 2023-07-01

    Proteomic clusters underlie heterogeneity in preclinical Alzheimer's disease progression

    ✓ Peer-reviewed Biomarkers Brain : a journal of neurology

    Key finding: Participants grouped by CSF trajectories were re-classified using only proteomic profiles (AUCAD Biomarker Positive versus AD Biomarker Negative = 0.857, AUCAD Biomarker Positive versus Intermediate AD Biomarkers = 0.525, AUCIntermediate AD Biomarkers versus AD Biomarker Negative = 0.952). +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-07-01

    Genetic architecture of plasma Alzheimer disease biomarkers

    ✓ Peer-reviewed Biomarkers Human molecular genetics

    Key finding: GWAS and gene-based analysis was used to identify single variant and genes associated with plasma levels. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2023-07-01

    Investigating three ways of measuring the intrinsic capacity domain of vitality: nutritional status, handgrip strength and ageing biomarkers

    ✓ Peer-reviewed Biomarkers Age and ageing

    Key finding: Vitality was associated with disability primarily through the mediation of other IC domains. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2023-07-01

    Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study

    ✓ Peer-reviewed Biomarkers Alzheimer's & Dementia

    Key finding: Circulating NfL and GFAP may, independently and jointly, provide useful clinical insight regarding dementia risk and prognosis. +3 more findings

    Full summary, score breakdown and related studies → Original source

June 2023 21

  1. 2023-06-30

    Functional and structural connectivity in the Papez circuit in different stages of Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    Key finding: The FC between the retrosplenial (RSC) and parahippocampal cortices (PHC) was the earliest affected FC, while a manifest SC change in the ventral cingulum and fornix was observed in the later ADD stage. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-06-30

    Neurofilament Light Chain as a Potential Biomarker in Plasma for Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and a Meta-Analysis

    ✓ Peer-reviewed Biomarkers Journal of integrative neuroscience

    Key finding: A total of 24 published articles that included 2397 AD and 3242 MCI patients were analysed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2023-06-30

    Mortality and Discharge Location of Intensive Care Patients With Alzheimer Disease and Related Dementia

    ✓ Peer-reviewed Health systems and care delivery American Journal of Critical Care

    Key finding: A total of 145 342 adults met inclusion criteria; 10.5% had ADRD and were likely to be older, female, and have more comorbid conditions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-06-29

    Diet and lifestyle impact the development and progression of Alzheimer's dementia

    ✓ Peer-reviewed Prevention and risk Frontiers in nutrition

    Key finding: Emerging epidemiological and clinical studies suggest that lifestyle changes, including diet and physical activity, offer an alternative therapeutic route for slowing and preventing cognitive decline and dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2023-06-29

    The Impact of Loneliness and Social Isolation on Cognitive Aging: A Narrative Review

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease reports

    Key finding: Studies have shown that there is an association between loneliness, social isolation, and reduced cognitive function, in older adults, across multiple cognitive domains, as well as a heightened risk of dementia.

    Full summary, score breakdown and related studies → Original source

  6. 2023-06-29

    ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer's Disease

    ✓ Peer-reviewed Drug development Biology

    Key finding: We found that DMF treatment did not result in modulating effects on Aβ deposition at this stage. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-06-29

    Alzheimer's disease biomarkers in cerebrospinal fluid are stable with the Elecsys immunoassay to most pre-analytical influencing factors except freezing at -80 °C

    ✓ Peer-reviewed Tau biomarkers Neurological research and practice

    Key finding: Alzheimer´s disease is considered a neurodegenerative disease and is diagnosed by exclusion, while the detection of specific cerebrospinal fluid (CSF) biomarkers, namely amyloid-beta (Aβ) peptides Aβ1-42 (Aß42), phospho-tau (181P; P-tau), and total-tau (T-tau), has been shown to improve diagnostic accuracy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-06-28

    Donanemab exposure and efficacy relationship using modeling in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (New York, N. Y.)

    Key finding: The plasma p-tau217 and plasma GFAP models adequately predicted the change over time, with donanemab resulting in decreased plasma p-tau217 and plasma GFAP concentrations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023-06-27

    Microbiome Alterations and Alzheimer's Disease: Modeling Strategies with Transgenic Mice

    ✓ Peer-reviewed Disease mechanisms Biomedicines

    Key finding: However, dysbiosis may provoke immune dysregulation, impacting neuroinflammation through peripheral-central immune communication. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2023-06-26

    Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes

    ✓ Peer-reviewed Drug development Drug design, development and therapy

    Key finding: It also decreases advanced glycation end products and reactive oxygen species production in the endothelium apart from regulating the glucose and lipid metabolism in the cardiomyocytes, hence minimizing the cardiovascular risks. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-06-26

    Identifying Medicare beneficiaries with Alzheimer's disease and related dementia using home health OASIS assessments

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: The most important predictors of having a diagnosis of ADRD by the start of care OASIS assessment were a prior discharge diagnosis of ADRD among those admitted from an inpatient setting, and frequently exhibiting symptoms of confusion. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2023-06-26

    The effects of low-dose radiation therapy in patients with mild-to-moderate Alzheimer's dementia: an interim analysis of a pilot study

    ✓ Peer-reviewed Treatments Radiation oncology journal

    Key finding: One of the five patients with AD treated with LDRT experienced a temporary improvement in SNSB-II.

    Full summary, score breakdown and related studies → Original source

  13. 2023-06-24

    "Life's Essential 8" Cardiovascular Health and Dementia Risk, Cognition, and Neuroimaging Markers of Brain Health

    ✓ Peer-reviewed Long-term cohort studies Journal of the American Medical Directors Association

    Key finding: Setting and participants A total of 316,669 participants [mean (SD) age, 56.3 (8.1) years] without prior cardiovascular disease or dementia from the UK Biobank study at baseline survey (2006-2010) were enrolled. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2023-06-24

    Protective effects of sleep duration and physical activity on cognitive performance are influenced by β-amyloid and brain volume but not tau burden among cognitively unimpaired older adults

    ✓ Peer-reviewed Biomarkers NeuroImage. Clinical

    Key finding: Sleep duration is linked to amyloid-β clearance while physical activity is associated with brain volume maintenance. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-06-23

    MRI in the new era of antiamyloid mAbs for the treatment of Alzheimer's disease

    ✓ Peer-reviewed Treatments Current opinion in neurology

    Key finding: Currently, three antibeta amyloid (Aβ) mAbs are approved or under examination in USA and in Europe for the treatment of patients with early Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  16. 2023-06-22

    Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of neurology, neurosurgery, and psychiatry

    Key finding: This study provides genetic evidence supporting the potential therapeutic benefits of targeting the three druggable genes for AD treatment, which will be useful for prioritising AD drug development. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2023-06-21

    Upregulation of endocytic protein expression in the Alzheimer's disease male human brain

    ✓ Peer-reviewed Biomarkers Aging brain

    Key finding: We hypothesised that endocytic protein expression would be altered in the brains of people with AD compared to non-diseased subjects which could be linked to increased Aβ generation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-06-19

    The intestinal microbiota as an ally in the treatment of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Gut microbiome (Cambridge, England)

    Key finding: This study, developed from a thorough systematic review, sought to demonstrate the influence of the intervention on the intestinal microbiota in subjects with Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-06-19

    Crosstalk between Alzheimer's disease and diabetes: a focus on anti-diabetic drugs

    ✓ Peer-reviewed Drug development Metabolic brain disease

    Key finding: Studies have demonstrated insulin pathway alternation may interact with amyloid-β protein deposition and tau protein phosphorylation, two essential factors in AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2023-06-19

    Recent Trends in Active and Passive Immunotherapies of Alzheimer's Disease

    ✓ Peer-reviewed Drug development Antibodies (Basel, Switzerland)

    Key finding: We examine their mechanisms of action and discuss the potential perspectives and challenges associated with immunotherapies for AD.

    Full summary, score breakdown and related studies → Original source

  21. 2023-06-19

    Altered resting-state functional connectivity patterns in late middle-aged and older adults with obstructive sleep apnea

    ✓ Peer-reviewed Brain scans and imaging Frontiers in neurology

    Key finding: In the whole sample, a higher apnea-hypopnea index was significantly associated with lower FC between (i) the medial prefrontal cortex and bilateral hippocampi, and (ii) the left hippocampus and both the posterior cingulate cortex and precuneus. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →