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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,426–7,450 of 27,380 studies, newest first · page 298 of 1096.

August 2023 25

  1. 2023-08-19

    Non-invasive Biomarkers for Early Detection of Alzheimer's Disease: a New-Age Perspective

    ✓ Peer-reviewed Brain scans and imaging Molecular neurobiology

    Key finding: It gradually leads to memory loss, loss of thinking ability, and an overall cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2023-08-19

    Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging

    ✓ Peer-reviewed Risk factors Archives of toxicology

    Key finding: Increased levels of ROS/RNS, generated from both endogenous (mitochondria, NADPH oxidases) and/or exogenous sources (radiation, certain drugs, foods, cigarette smoking, pollution) result in a harmful condition termed oxidative stress ("bad stress").

    Full summary, score breakdown and related studies → Original source

  3. 2023-08-18

    ApoE4 exacerbates the senescence of hippocampal neurons and spatial cognitive impairment by downregulating acetyl-CoA level

    ✓ Peer-reviewed Genetics Aging cell

    Key finding: Using humanized ApoE4- and ApoE3- target replacement mice, we found the accumulation of senescent neurons and the activation of mTOR and endosome-lysosome-autophagy (ELA) system in the hippocampus of aged ApoE4 mice. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-08-17

    Generative Adversarial Network-Enhanced Ultra-Low-Dose [18F]-PI-2620 τ PET/MRI in Aging and Neurodegenerative Populations

    ✓ Peer-reviewed Brain scans and imaging AJNR. American journal of neuroradiology

    Key finding: The enhanced ultra-low-dose τ images showed apparent noise reduction compared with the ultra-low-dose images. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2023-08-17

    Apolipoprotein E isoform does not influence trans-synaptic spread of tau pathology in a mouse model

    ✓ Peer-reviewed Genetics Brain and neuroscience advances

    Key finding: Apolipoprotein E4 (APOE4) genotype is the strongest genetic risk factor for late-onset AD and is associated with increased tau burden. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023-08-17

    Roles of Oxidative Stress in Synaptic Dysfunction and Neuronal Cell Death in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Antioxidants (Basel, Switzerland)

    Key finding: The main histopathological hallmarks of AD are the presence of abnormal protein aggregates (Aβ and tau), synaptic dysfunction, aberrant proteostasis, cytoskeletal abnormalities, altered energy homeostasis, DNA and RNA defects, inflammation, and neuronal cell death. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-08-16

    Platelet factors attenuate inflammation and rescue cognition in ageing

    ✓ Peer-reviewed Inflammation and the immune system Nature

    Key finding: Here we show that platelet factors transfer the benefits of young blood to the ageing brain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-08-16

    Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort

    ✓ Peer-reviewed Long-term cohort studies Aging cell

    Key finding: Here, we investigate associations between a panel of inflammatory biomarkers and cognitive function and incident dementia outcomes in the well-characterized Framingham Heart Study Offspring cohort. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023-08-16

    Eligibility for Anti-Amyloid Treatment in a Population-Based Study of Cognitive Aging

    ✓ Peer-reviewed Drug development Neurology

    Key finding: Treatment options for Alzheimer disease (AD) are limited and have focused mainly on symptomatic therapy and improving quality of life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2023-08-16

    Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: Microglia, the brain's principal immune cells, have been implicated in the pathogenesis of Alzheimer's disease (AD), a condition shown to affect more females than males. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-08-15

    Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of disease

    Key finding: TREM2-R47H mice showed increased seizure activity in response to an acute excitotoxin challenge, compared to wildtype controls or knockin mice expressing the common variant of human TREM2. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2023-08-14

    Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models

    ✓ Peer-reviewed TREM2 and immune genetics The EMBO journal

    Key finding: Genetic studies in AD support that microglia act as potential cellular drivers of disease risk, but the molecular determinants of microglia-synapse engulfment associated with neuronal hyperactivity in AD are unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-08-14

    Association of Plasma Biomarkers of Alzheimer Disease With Cognition and Medical Comorbidities in a Biracial Cohort

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: We observed no differences in plasma AD biomarker levels between AA and NHW participants. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2023-08-12

    A Systematic Compilation of Human SH3 Domains: A Versatile Superfamily in Cellular Signaling

    ✓ Peer-reviewed Prevention trials Cells

    Key finding: They are widely studied modular building blocks across all five kingdoms of life and viruses, mediating various biological processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-08-12

    Neuropsychiatric symptoms in people living with dementia receiving home health services

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: Participants identified as non-Hispanic White (50%), non-Hispanic Black (30%), or Hispanic (13%). +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2023-08-11

    Utility of amyloid PET Imaging in a Memory Clinic

    ✓ Peer-reviewed Brain scans and imaging Alzheimer disease and associated disorders

    Key finding: Of the 30 patients with negative amyloid PET scan results, 90% had a diagnosis of non-AD etiology after receiving the negative results, suggesting a negative amyloid scan can be used to rule out AD diagnosis.

    Full summary, score breakdown and related studies → Original source

  17. 2023-08-11

    Two distinct molecular faces of preeclampsia revealed by single-cell transcriptomics

    ✓ Peer-reviewed TREM2 and immune genetics Med (New York, N.Y.)

    Key finding: Preeclampsia is a multisystemic, pregnancy-specific disorder united by new-onset hypertension but with considerable variation in clinical manifestation, onset, and severity. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-08-10

    Limbic-predominant age-related TDP43 encephalopathy (LATE) neuropathological change in neurodegenerative diseases

    ✓ Peer-reviewed Brain tissue and pathology Nature reviews. Neurology

    Key finding: LATE-NC is frequently associated with one or more coexisting pathologies, mainly AD neuropathological change. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2023-08-10

    Target delivery of a PD-1-TREM2 scFv by CAR-T cells enhances anti-tumor efficacy in colorectal cancer

    ✓ Peer-reviewed TREM2 and immune genetics Molecular cancer

    Key finding: Chimeric antigen receptor (CAR) -T cell therapy is an efficient therapeutic strategy for specific hematologic malignancies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2023-08-10

    Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The literature has several methodological limitations including lack of sufficient algorithm development descriptions and standard definitions.

    Full summary, score breakdown and related studies → Original source

  21. 2023-08-09

    Cerebral Amyloid Angiopathy-Related Inflammation: A Case Report and Literature Review

    ✓ Peer-reviewed Vascular contributions Journal of the Korean Society of Radiology

    Key finding: Cerebral amyloid angiopathy-related inflammation (CAA-RI) is an encephalopathy caused by inflammation of β-amyloid peptide deposition in cerebrovascular vessels. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-08-09

    Genetics of Alzheimer's Disease in the African American Population

    ✓ Peer-reviewed Genetics Journal of clinical medicine

    Key finding: Black/African American (AA) individuals have a higher risk of Alzheimer's disease (AD) than White non-Hispanic persons of European ancestry (EUR) for reasons that may include economic disparities, cardiovascular health, quality of education, and biases in the methods used to diagnose AD.

    Full summary, score breakdown and related studies → Original source

  23. 2023-08-08

    Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: General baseline characteristics of the study population were mean (standard deviation) age, 58.1 (8.8) years; 47% women. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2023-08-08

    High diagnostic performance of plasma and cerebrospinal fluid beta-synuclein for sporadic Creutzfeldt-Jakob disease

    ✓ Peer-reviewed Biomarkers Annals of clinical and translational neurology

    Key finding: Beta-synuclein is a promising cerebrospinal fluid and blood biomarker of synaptic damage. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2023-08-07

    Management of neuropsychiatric symptoms in dementia

    ✓ Peer-reviewed Clinical trials Current opinion in neurology

    Key finding: RECENT FINDINGS: In a large autopsy series from a national consortium, multiple neuropathologies of dementia subtypes were common and increased severity of specific NPS during life was associated with greater severity of neuropathology across diagnoses. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →