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48/100

✓ Peer-reviewed alzhub usefulness score 48 out of 100. Brain scans and imaging

Topic: Brain imaging, connectivity and assessment

The FC between the retrosplenial (RSC) and parahippocampal cortices (PHC) was the earliest affected FC, while a manifest SC change in the ventral cingulum and fornix was observed in the later ADD stage. The RSC-PHC FC and the ventral cingulum FA efficiently predicted the memory performance of the non-demented participants. Our findings revealed the importance of the Papez circuit as target regions along the AD. The ventral cingulum connecting the RSC and PHC, a critical overlap area between the Papez circuit and the default mode network, seems to be a target region associated with the earliest objective memory findings in AD.

Key findings

The FC between the retrosplenial (RSC) and parahippocampal cortices (PHC) was the earliest affected FC, while a manifest SC change in the ventral cingulum and fornix was observed in the later ADD stage.
The RSC-PHC FC and the ventral cingulum FA efficiently predicted the memory performance of the non-demented participants.
Our findings revealed the importance of the Papez circuit as target regions along the AD.
The ventral cingulum connecting the RSC and PHC, a critical overlap area between the Papez circuit and the default mode network, seems to be a target region associated with the earliest objective memory findings in AD.

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Study details

Participants15
Evidence strengthLow

How this study scored 48/100

Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 27 of the 56 points we could judge it on, which is 48 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology)
Journal's citation record	— / 4	No journal record from OpenAlex — left out of this score
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	3 / 5	2023 — within 6 year(s) of the newest study here
Sample size	1 / 4	15 participants
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	— / 7	No citation count (not found in OpenAlex) — left out of this score
Citations per year	— / 5	No citation count or no year — left out of this score
Impact for its field and year	— / 6	No field-weighted citation impact (OpenAlex has none yet) — left out of this score
Cited by studies here	— / 6	Not yet checked against this library's citation graph — left out of this score
Still being cited	— / 4	No yearly citation counts — left out of this score
Senior author's track record	— / 4	Senior author's record not available — left out of this score
Institution's track record	— / 3	No institution listed in OpenAlex — left out of this score
Multi-centre collaboration	— / 3	Institutions not listed — left out of this score
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 37451080)
Free to read	— / 2	Access not recorded — left out of this score
Points	27 / 56	Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 27 of the 56 points we could judge it on is 48 out of 100.
Total	48 / 100	—

What each of these 20 components measures, and what this score is not →

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Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.

APA 7th

Hari, E., Kizilates-Evin, G., Kurt, E., Bayram, A., Ulasoglu-Yildiz, C., Gurvit, H., et al. (2023). Functional and structural connectivity in the Papez circuit in different stages of Alzheimer's disease. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. https://doi.org/10.1016/j.clinph.2023.06.008

Vancouver

Hari E, Kizilates-Evin G, Kurt E, Bayram A, Ulasoglu-Yildiz C, Gurvit H, et al. Functional and structural connectivity in the Papez circuit in different stages of Alzheimer's disease. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2023. doi:10.1016/j.clinph.2023.06.008. PMID: 37451080.

BibTeX

@article{hari2023-37451080,
  author  = {Hari, Emre and Kizilates-Evin, Gozde and Kurt, Elif and Bayram, Ali and Ulasoglu-Yildiz, Cigdem and Gurvit, Hakan and Demiralp, Tamer},
  title   = {{Functional and structural connectivity in the Papez circuit in different stages of Alzheimer's disease}},
  journal = {Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology},
  year    = {2023},
  doi     = {10.1016/j.clinph.2023.06.008},
  pmid    = {37451080},
  url     = {https://doi.org/10.1016/j.clinph.2023.06.008}
}

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