alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,626–7,650 of 27,380 studies, newest first · page 306 of 1096.

June 2023 6

  1. 2023-06-01

    Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated

    ✓ Peer-reviewed Caregiving Brain : a journal of neurology

    Key finding: The presence of multiple additive pathologies associated with older age, increasing disease duration, APOE e4 allele and presence of dementia across the clinical groups. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2023-06-01

    [The past, present and future of sleep medicine in China]

    ✓ Peer-reviewed Getting a diagnosis Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

    Key finding: After decades of development, researchers have made great progress in the molecular mechanisms of sleep and wakefulness, the pathogenesis of sleep disorders and the development of new therapies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2023-06-01

    Patterns of Regional Brain Atrophy and Brain Aging in Middle- and Older-Aged Adults With Type 1 Diabetes

    ✓ Peer-reviewed Treatments JAMA network open

    Key finding: EDIC participants had consistently higher brain age values compared with controls without diabetes, indicative of approximately 6 additional years of brain aging (EDIC participants: β, 6.16; SE, 0.71; control participants: β, 1.04; SE, 0.04; P Conclusions and relevance The findings of this study suggest an increase in brain aging among individuals with T1D without any early signs of AD-related neurodegeneration. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-06-01

    Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Baseline and 3-month visit data were available for 272 participants in arm 1 and 260 in arm 2 (median [IQR] age: 71 [65-77] and 71 [65-77] years; 150/272 male [55%] and 135/260 male [52%]; 122/272 female [45%] and 125/260 female [48%]; median [IQR] education: 12 [10-15] and 13 [10-16] years, respectively). +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2023-06-01

    Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews

    ✓ Peer-reviewed Genetics Alzheimer's & Dementia

    Key finding: Our results highlight the efficacy of founder populations for AD genetic studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023-06-01

    Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia

    ✓ Peer-reviewed Prevention and risk JAMA Psychiatry

    Key finding: Further studies are warranted to develop and refine the specific MIND diet for different populations. +3 more findings

    Full summary, score breakdown and related studies → Original source

May 2023 19

  1. 2023-05-31

    The functional role of the precuneus

    ✓ Peer-reviewed Brain scans and imaging Brain

    Key finding: Fortunately, recent studies have revealed significant information on the structural and functional connectivity of this region, and this data has provided a more detailed mechanistic understanding of the importance of the precuneus in healthy and pathologic states. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-05-31

    Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease

    ✓ Peer-reviewed How common it is Nature

    Key finding: Brain ageing affects oligodendrocytes and the structural integrity of myelin sheaths 1 , the latter of which is associated with secondary neuroinflammation 2,3 . +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2023-05-31

    Association of Sleep-Disordered Breathing and Medial Temporal Lobe Atrophy in Cognitively Unimpaired Amyloid-Positive Older Adults

    ✓ Peer-reviewed Treatments Neurology

    Key finding: Overall, we showed that SDB was associated with MTL atrophy in cognitively asymptomatic older adults engaged in the Alzheimer continuum, which may increase the risk of developing memory impairment over time. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-05-30

    Loneliness - Cancer of the Mind

    ✓ Peer-reviewed Risk factors Indian journal of palliative care

    Key finding: Off late, the deleterious health implication of social isolation and loneliness has increasingly been noticed, with a higher risk of premature death and accelerated risks of coronary heart disease, stroke, depression, and dementia.

    Full summary, score breakdown and related studies → Original source

  5. 2023-05-30

    Drug Repurposing in Oncology: A Systematic Review of Randomized Controlled Clinical Trials

    ✓ Peer-reviewed Drug development Cancers

    Key finding: We found that only a few clinical trials were placebo-controlled or standard-of-care-alone-controlled.

    Full summary, score breakdown and related studies → Original source

  6. 2023-05-29

    Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health

    ✓ Peer-reviewed Genetics Nature communications

    Key finding: Retromer controls cellular homeostasis through regulating integral membrane protein sorting and transport and by controlling maturation of the endo-lysosomal network. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-05-29

    Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease

    ✓ Peer-reviewed Laboratory science Nature Medicine

    Key finding: An unresolved question for the understanding of Alzheimer's disease (AD) pathophysiology is why a significant percentage of amyloid-β (Aβ)-positive cognitively unimpaired (CU) individuals do not develop detectable downstream tau pathology and, consequently, clinical deterioration. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-05-27

    Sleep and Women's Mental Health

    ✓ Peer-reviewed Risk factors The Psychiatric clinics of North America

    Key finding: Women have a higher prevalence of insomnia disorder and restless legs syndrome (RLS) versus men, and obstructive sleep apnea (OSA) is more likely as women age. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2023-05-27

    Levels of Alzheimer's disease blood biomarkers are altered after food intake-A pilot intervention study in healthy adults

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Our data suggest that AD-related biomarkers are altered by food intake. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2023-05-26

    Effects of GLP-1 receptor agonists on neurological complications of diabetes

    ✓ Peer-reviewed Drug development Reviews in endocrine & metabolic disorders

    Key finding: Emerging evidence suggests that treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) could be an interesting treatment strategy to reduce neurological complications such as stroke, cognitive impairment, and peripheral neuropathy. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-05-26

    Total Chemical Synthesis of Glycosylated TREM2 Ectodomain

    ✓ Peer-reviewed TREM2 and immune genetics ACS chemical neuroscience

    Key finding: Here, we present the total chemical synthesis of the 116 amino acid TREM2 ectodomain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2023-05-26

    Neurofilament light chain and cardiac MIBG uptake as predictors for phenoconversion in isolated REM sleep behavior disorder

    ✓ Peer-reviewed Biomarkers Journal of neurology

    Key finding: Patients were followed for a median of 2.92 years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-05-26

    Physical activity and lifestyle modifications in the treatment of neurodegenerative diseases

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: Neurodegenerative diseases have reached alarming numbers in the past decade. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2023-05-26

    Preanalytical stability of plasma/serum brain-derived tau

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We investigated the effects of matrix type and reagent batch changes on diagnostic performances and longitudinal trajectories of brain-derived tau (BD-tau). +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-05-26

    Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adults

    ✓ Peer-reviewed Biomarkers GeroScience

    Key finding: Between adropin tertiles, ∆CCS was significantly different (P = 0.01; estimated marginal mean ± SE for the 1st to 3rd tertile, - 0.317 ± 0.064; - 0.275 ± 0.063; - 0.042 ± 0.071; n = 133,146, and 130, respectively; P < 0.05 for 1st vs. 2nd and 3rd adropin tertiles). +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2023-05-25

    Tau accumulation in autosomal dominant Alzheimer's disease: a longitudinal [18F]flortaucipir study

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: Cortical tau accumulation is a key pathological event that partly defines Alzheimer's disease (AD) onset and is associated with cognitive decline and future disease progression. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2023-05-25

    Roles of ApoE4 on the Pathogenesis in Alzheimer's Disease and the Potential Therapeutic Approaches

    ✓ Peer-reviewed Genetics Cellular and molecular neurobiology

    Key finding: Emerging epidemiological evidence indicated that ApoE4 contributes to AD through influencing β-amyloid (Aβ) deposition and clearance.

    Full summary, score breakdown and related studies → Original source

  18. 2023-05-25

    The Use of Telehealth Among People Living With Dementia-Caregiver Dyads During the COVID-19 Pandemic: Scoping Review

    ✓ Peer-reviewed Health systems and care delivery Journal of medical Internet research

    Key finding: The inclusion criteria for peer-reviewed English publications from March 2020 to August 2022 consisted of studies related to telehealth services for people living with dementia and their family caregivers and studies conducted during the COVID-19 pandemic. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-05-24

    Dyadic Hair Cortisol Self-Collection Procedure

    ✓ Peer-reviewed Caregiving Nursing research

    Key finding: At-home, self-collection of hair provides potential advantages such as reduced participant burden, especially for vulnerable populations where transportation and different environments are challenging. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →