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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,251–7,275 of 27,380 studies, newest first · page 291 of 1096.

October 2023 25

  1. 2023-10-21

    Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis

    ✓ Peer-reviewed Disease mechanisms Acta pharmaceutica Sinica. B

    Key finding: Accordingly, we designed an RP-1 peptide-modified reactive oxygen species (ROS)-responsive micelles (RT-NM) loading rapamycin or gypenoside XVII. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-10-21

    Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Nature communications

    Key finding: The proteolytic shedding of TREM2 results in the release of soluble TREM2 (sTREM2), which is increased in the cerebrospinal fluid of patients with Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2023-10-19

    Retina Oculomics in Neurodegenerative Disease

    ✓ Peer-reviewed Brain scans and imaging Annals of biomedical engineering

    Key finding: With the advent of increasingly large ophthalmic imaging datasets, machine learning models can be integrated into these ocular imaging biomarkers to provide further insights and prognostic predictions of neurodegenerative disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-10-18

    Caring for Dementia Caregivers: Psychosocial Factors Related to Engagement in Self-Care Activities

    ✓ Peer-reviewed Caregiving Behavioral sciences (Basel, Switzerland)

    Key finding: Caregivers often prioritize the needs of the care recipient and neglect their own health needs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2023-10-18

    Synthesis and Bioevaluation of 2-Styrylquinoxaline Derivatives as Tau-PET Tracers

    ✓ Peer-reviewed Drug development Molecular pharmaceutics

    Key finding: The compound [18F]15, which had two ethoxy units, showed high affinity for recombinant K18-Tau aggregates (Ki = 41.48 nM) and the highest selectivity versus Aβ1-42 aggregates (8.83-fold). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2023-10-17

    Out-of-Pocket Expenses for Long-Term Care by Dementia Status and Residential Setting among US Older Adults

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association

    Key finding: Among 4505 respondents aged ≥70 years, 1750 (38.8%) had possible or probable dementia and 2755 (61.2%) had no dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-10-17

    Metformin, age-related cognitive decline, and brain pathology

    ✓ Peer-reviewed Drug development Neurobiology of aging

    Key finding: Using a linear-mixed effect model adjusted for age, sex, and education, metformin users had slower decline on a score of global cognition compared to non-users (estimate = 0.017, SE = 0.007, p = 0.027). +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2023-10-17

    Pervasive biases in proxy GWAS based on parental history of Alzheimer's disease

    ⚠ Preprint — not yet peer-reviewed Genetics bioRxiv : the preprint server for biology

    Key finding: Here, we report major limitations in current GWAS-by-proxy (GWAX) practices due to uncorrected survival bias and non-random participation of parental illness survey, which cause substantial discrepancies between AD GWAS and GWAX results. +1 more finding

    Scored 47 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  9. 2023-10-17

    Novel Alzheimer's disease genes and epistasis identified using machine learning GWAS platform

    ✓ Peer-reviewed Genetics Scientific reports

    Key finding: By incorporating significant epistatic interactions, we captured 10.41% more phenotypic variance than logistic regression (LR). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2023-10-17

    A Spatial Variance‐Smoothing Area Level Model for Small Area Estimation of Demographic Rates

    ✓ Peer-reviewed Risk factors International Statistical Review

    Key finding: We demonstrate the performance of our approach via simulation and application to vaccination coverage and HIV prevalence data from the Demographic and Health Surveys. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-10-16

    Influence of Alzheimer's disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex

    ✓ Peer-reviewed Genetics GEN biotechnology

    Key finding: We identified transcriptomic signatures associated with proximity to Aβ in the human inferior temporal cortex (ITC) during late-stage AD, which we further investigated at cellular resolution with combined immunofluorescence and single molecule fluorescent in situ hybridization (smFISH). +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2023-10-16

    Accelerating Alzheimer's therapeutic development: The past and future of clinical trials

    ✓ Peer-reviewed Brain scans and imaging Cell

    Key finding: Biomarkers of the target pathologies, including amyloid and tau PET, and insights from past trials were also critical to the recent successes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-10-14

    Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Alzheimer's research & therapy

    Key finding: After a PRISMA analysis, 29 articles revealed a trend towards using multimodal algorithms that incorporate additional biomarkers such as neuroimaging, neuropsychological tests, and genetic information. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2023-10-13

    A comparative atlas of single-cell chromatin accessibility in the human brain

    ✓ Peer-reviewed Genetics Science (New York, N.Y.)

    Key finding: Nearly a third of the cCREs demonstrated conservation and chromatin accessibility in the mouse brain cells.

    Full summary, score breakdown and related studies → Original source

  15. 2023-10-13

    Neurodegenerative Disease Tauopathies

    ✓ Peer-reviewed Disease mechanisms Annual review of pathology

    Key finding: Tau protein forms pathologic fibrillar aggregates that are typically closely associated with neuronal cell death, leading to varied clinical phenotypes including dementia, movement disorders, and motor neuron disease.

    Full summary, score breakdown and related studies → Original source

  16. 2023-10-13

    Prevalence of Diagnosed Arthritis - United States, 2019-2021

    ⚠ Report — not peer-reviewed Disparities MMWR. Morbidity and mortality weekly report

    Key finding: It is a leading cause of activity limitations, disability, and chronic pain, and is associated with dispensed opioid prescriptions, substantially contributing to health care costs.

    Scored 32 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  17. 2023-10-13

    Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial

    ✓ Peer-reviewed Treatments JMIR research protocols

    Key finding: Caregiver stress is associated with negative outcomes for both caregivers and care recipients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-10-13

    High intake of ultra-processed food is associated with dementia in adults: a systematic review and meta-analysis of observational studies

    ✓ Peer-reviewed Prevention and risk Journal of Neurology

    Key finding: High UPF consumption is associated with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-10-12

    Advance care planning and outpatient visits among older adults across cognitive levels

    ✓ Peer-reviewed End-of-life care Aging and health research

    Key finding: Our findings indicated that having at least one ACP measure was significantly associated with a higher mean number of outpatient visits in both cognition groups. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2023-10-12

    Integrating spatial transcriptomics data across different conditions, technologies and developmental stages

    ✓ Peer-reviewed Digital health tools Nature computational science

    Key finding: With the rapid generation of spatial transcriptomics (ST) data, integrative analysis of multiple ST datasets from different conditions, technologies and developmental stages is becoming increasingly important. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2023-10-12

    The Memory Alteration Test Is Correlated with Clinical, Cerebrospinal Fluid, and Brain Imaging Markers of Alzheimer Disease in Lima, Peru

    ✓ Peer-reviewed Tau biomarkers Dementia and geriatric cognitive disorders

    Key finding: As disease-modifying therapies become available for Alzheimer's disease (AD), detection of AD in early stages of illness (mild cognitive impairment [MCI], early dementia) becomes increasingly important. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-10-11

    Synaptic Compensatory Plasticity in Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Although much is known about the mechanisms underlying synaptic loss in AD, how neurons compensate for this loss and whether this provides cognitive benefits remain almost completely unexplored. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2023-10-11

    Role of diet and exercise in aging, Alzheimer's disease, and other chronic diseases

    ✓ Peer-reviewed Risk factors Ageing research reviews

    Key finding: Antioxidant enriched diet contributes to brain health, glucose control, weight management, and cardiovascular well-being. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2023-10-11

    Blood biomarker-based classification study for neurodegenerative diseases

    ✓ Peer-reviewed Biomarkers Scientific reports

    Key finding: We demonstrated that convolutional neural networks perform consistently well across both the Alzheimer's (ROC AUC = 0.810) and Parkinson's (ROC AUC = 0.715) datasets, suggesting its potential in gene expression biomarker detection with increased tuning of their architecture.

    Full summary, score breakdown and related studies → Original source

  25. 2023-10-11

    Clinical safety and efficacy of allogenic human adipose mesenchymal stromal cells-derived exosomes in patients with mild to moderate Alzheimer's disease: a phase I/II clinical trial

    ✓ Peer-reviewed Hippocampus size on brain scans General psychiatry

    Key finding: Intranasal administration of ahaMSCs-Exos was safe and well tolerated, and a dose of at least 4×10 8 particles could be selected for further clinical trials. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →