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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,501–7,525 of 27,380 studies, newest first · page 301 of 1096.

July 2023 25

  1. 2023-07-17

    Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial

    ✓ Peer-reviewed Clinical trials JAMA

    Key finding: n=1,736 (860 donanemab, 876 placebo); 76-week Phase 3 trial across 277 sites in 8 countries +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-07-16

    Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's disease

    ⚠ Preprint — not yet peer-reviewed Tau biomarkers medRxiv : the preprint server for health sciences

    Key finding: SuStaIn revealed in the two cohorts that the data was best explained by a single biomarker sequence (one subtype), and that five CSF biomarkers (ordered: Aβ42/40, tau phosphorylation occupancies at the residues 217 and 205 [pT217/T217 and pT205/T205], microtubule-binding region of tau containing the residue 243 [MTBR-tau243], and total tau) were sufficient to create an accurate disease staging model. +3 more findings

    Scored 43 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  3. 2023-07-16

    ADAM10 as a biomarker for Alzheimer's disease: A systematic review

    ✓ Peer-reviewed Risk genes beyond APOE Revue neurologique

    Key finding: Evidence shows that ADAM10 levels are altered in platelets, plasma, serum, and CSF of individuals with AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2023-07-15

    Promoting Healthy Aging: Public Health as a Leader for Reducing Dementia Risk

    ⚠ Report — not peer-reviewed Risk factors Public Policy & Aging Report

    Key finding: It is estimated that for people aged 65 years and older, the risk of developing Alzheimer’s disease was nearly double for women compared with men (Weinstein et al., 2012). +4 more findings

    Scored 26 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  5. 2023-07-14

    Health Care Resource Use and Social Costs in Mild Cognitive Impairment and Mild Alzheimer's Disease

    ✓ Peer-reviewed Caregiving Journal of Alzheimer's disease reports

    Key finding: Patients with mild AD had higher total costs, patient medical costs, patient social care costs, and family caregiver informal care costs than did patients with MCI; however, only patient medical costs were significantly different (p = 0.022). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023-07-14

    Microglia regulation of central nervous system myelin health and regeneration

    ✓ Peer-reviewed Inflammation and the immune system Nature reviews. Immunology

    Key finding: Although microglia have been increasingly implicated in contributing to the pathology that underpins neurological dysfunction and disease, they also have crucial roles in neurological homeostasis and regeneration. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2023-07-14

    Tau and neuroinflammation in Alzheimer's disease: interplay mechanisms and clinical translation

    ✓ Peer-reviewed Inflammation and the immune system Journal of neuroinflammation

    Key finding: Its prominent neuropathological features are the extracellular neuritic plaques and intercellular neurofibrillary tangles composed of aggregated β-amyloid (Aβ) and hyperphosphorylated tau protein, respectively. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-07-13

    Analysis of Japanese nationwide health datasets: association between lifestyle habits and prevalence of neuropathic pain and fibromyalgia with reference to dementia-related diseases and Parkinson's disease

    ✓ Peer-reviewed Health systems and care delivery Scandinavian journal of pain

    Key finding: This study focuses on neuropathic pain (NP) and fibromyalgia (FM) which are chronic pain states, and aims to identify lifestyle habits associated with their prevalence. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023-07-13

    Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project

    ✓ Peer-reviewed Digital health tools The lancet. Healthy longevity

    Key finding: We aimed to characterise the brain structure of superagers and identify demographic, lifestyle, and clinical factors associated with this phenotype. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2023-07-13

    CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Nature medicine

    Key finding: Because clinical symptoms are strongly correlated with tau aggregates, drug development and clinical diagnosis need cost-effective and accessible specific fluid biomarkers of tau aggregates; however, recent studies suggest that the fluid biomarkers currently available cannot specifically track tau aggregates. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2023-07-12

    White matter hyperintensities and Alzheimer's disease: An alternative view of an alternative hypothesis

    ✓ Peer-reviewed Vascular contributions Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: White matter hyperintensities (WMH) - - areas of increased signal appearing on T2-weighted magnetic resonance imaging - - are associated with Alzheimer’s disease (AD) risk and progression in late onset and genetic forms.

    Full summary, score breakdown and related studies → Original source

  12. 2023-07-12

    Grey matter volume and CSF biomarkers predict neuropsychological subtypes of MCI

    ✓ Peer-reviewed Tau biomarkers Neurobiology of aging

    Key finding: In our study, we demonstrated that MCI participants of the ADNI database (N = 640) can be discriminated into 3 coherent neuropsychological subgroups. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-07-12

    Role of neuroinflammation in neurodegeneration development

    ✓ Peer-reviewed Inflammation and the immune system Signal transduction and targeted therapy

    Key finding: Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that inflammation is not only a result of neurodegeneration but also a crucial player in this process. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2023-07-12

    Alzheimer`s disease mortality in the United States: Cross-sectional analysis of county-level socio-environmental factors

    ✓ Peer-reviewed Risk factors Archives of gerontology and geriatrics

    Key finding: Therefore, we aimed to explore high-risk SEDH factors possibly associated with all-cause mortality in AD across US counties using machine learning (ML) methods. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2023-07-12

    TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

    ✓ Peer-reviewed TREM2 and immune genetics Immunity

    Key finding: Here, we found that TREM2 specifically attenuated the activation of classical complement cascade via high-affinity binding to its initiator C1q. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2023-07-11

    Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

    ✓ Peer-reviewed Risk factors Molecular neurodegeneration

    Key finding: In VCID, cerebral small vessel disease (cSVD) often affects arterioles, capillaries, and venules, where arteriolosclerosis and cerebral amyloid angiopathy (CAA) are major pathologies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2023-07-10

    Clinical development of passive tau-based immunotherapeutics for treating primary and secondary tauopathies

    ✓ Peer-reviewed Drug development Expert opinion on investigational drugs

    Key finding: Tauopathies are clinicopathological entities with increased and pathological deposition in glia and/or neurons of hyperphosphorylated aggregates of the microtubule-binding protein tau. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2023-07-10

    Optical Coherence Tomography Assessment of Macular Thickness in Alzheimer's Dementia with Different Neuropsychological Severities

    ✓ Peer-reviewed Brain scans and imaging Journal of personalized medicine

    Key finding: AD patients had significant reductions in full macula layers, including inner circle, outer inferior area, and outer nasal area of the macula. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-07-10

    Blood-based biomarkers for Alzheimer's disease: a multicenter-based cross-sectional and longitudinal study in China

    ✓ Peer-reviewed Biomarkers Science bulletin

    Key finding: A combination of the APOE genotype with plasma pTau and serum GFAP demonstrated exceptional performance in distinguishing Aβ status. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2023-07-08

    Racial-Ethnic Disparities in Dual-Function Life Expectancy

    ✓ Peer-reviewed Disparities The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: At ages 50-54, between 79.0% (95% CI: 73.5, 84.5) and 87.6% (95% CI: 84.0, 91.2) of (non-Hispanic) Black, foreign-born Hispanic, and U.S.-born Hispanic women and men remain dual functional as compared with 90.4% (95% CI: 89.3, 91.4) and 91.4% (95% CI: 90.2, 92.5) of (non-Hispanic) White women and men, respectively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2023-07-08

    Novel aspects of the phosphorylation and structure of pathological tau: implications for tauopathy biomarkers

    ✓ Peer-reviewed Biomarkers FEBS open bio

    Key finding: Recent advances in analytical techniques revealed the details of the biochemical and structural biological differences of tau specific to each tauopathy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2023-07-08

    Physical activity, biomarkers of brain pathologies and dementia risk: Results from the Memento clinical cohort

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Physical activity moderated the association between MTA and plasma Aβ42/40 level and increased dementia risk. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2023-07-08

    AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Journal of biomedical informatics

    Key finding: The use of EHRs for AD-related research is promising, and AD-BERT shows superior predictive performance in modeling MCI-to-AD progression prediction.

    Full summary, score breakdown and related studies → Original source

  24. 2023-07-08

    Incidence and Risk Factors of Falls Among Older People in Nursing Homes: Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Clinical safety Journal of the American Medical Directors Association

    Key finding: The results from our meta-analysis suggest that the incidence of falls of older adults living in nursing homes is high, and the risk factors for falls are various. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2023-07-08

    Anxiety adds the risk of cognitive progression and is associated with axon/synapse degeneration among cognitively unimpaired older adults

    ✓ Peer-reviewed Long-term cohort studies EBioMedicine

    Key finding: Mental symptoms have been shown to be associated with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →