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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 7,351–7,375 of 27,380 studies, newest first · page 295 of 1096.

September 2023 25

  1. 2023-09-14

    Technology caregiver intervention for Alzheimer's disease (I-CARE): Feasibility and preliminary efficacy of Brain CareNotes

    ✓ Peer-reviewed Caregiving Journal of the American Geriatrics Society

    Key finding: The enrollment rate was acceptable despite pandemic related challenges (53/60 target recruitment sample). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2023-09-14

    Orexin Receptor Antagonism: Normalizing Sleep Architecture in Old Age and Disease

    ✓ Peer-reviewed Risk factors Annual review of pharmacology and toxicology

    Key finding: Indeed, several clinical studies indicate that ORAs are efficacious hypnotics in older persons and dementia patients and, as in adults, are generally well tolerated.

    Full summary, score breakdown and related studies → Original source

  3. 2023-09-13

    CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease

    ✓ Peer-reviewed Tau biomarkers Nature communications

    Key finding: This DLB CSF proteome study identifies DLB-specific protein changes and translates these findings to a practicable biomarker panel that accurately identifies DLB patients, providing promising diagnostic and clinical trial testing opportunities.

    Full summary, score breakdown and related studies → Original source

  4. 2023-09-13

    Effect of Neurotoxin Exposure on Blood Biomarkers of Neurodegeneration and Alzheimer Disease

    ✓ Peer-reviewed Tau biomarkers Alzheimer disease and associated disorders

    Key finding: Blood cadmium, lead, neurofilament light (NfL) chain, total tau (TTau), and amyloid beta (Aβ) 40 and Aβ42 concentrations were measured in 1516 participants in the Beaver Dam Offspring Study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2023-09-12

    Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties

    ✓ Peer-reviewed Treatments European journal of medicinal chemistry

    Key finding: Unfortunately, it showed a suboptimal pharmacokinetic profile, which required intracerebroventricular administration for in vivo studies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2023-09-12

    Transcriptomic Analysis in the Hippocampus and Retina of Tg2576 AD Mice Reveals Defective Mitochondrial Oxidative Phosphorylation and Recovery by Tau 12A12mAb Treatment

    ✓ Peer-reviewed Drug development Cells

    Key finding: The results revealed that oxidative phosphorylation and mitochondrial-related pathways are significantly down-regulated in both tissues of Tg2576 mice, supporting the role of these processes in the pathogenesis of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2023-09-12

    The roles of apolipoprotein E ε4 on neuropathology and neuroinflammation in patients with Alzheimer's disease

    ✓ Peer-reviewed Genetics CNS neuroscience & therapeutics

    Key finding: β amyloid protein (Aβ)1-42 level from the APOE ε4 carrier group was significantly lower than that from the non-carrier group (p = 0.023), which was associated with worse cognitive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2023-09-11

    Carbamate as a potential anti-Alzheimer's pharmacophore: A review

    ✓ Peer-reviewed Treatments Drug development research

    Key finding: So, there is an urgent need for novel drug development that not only addresses the basic mechanisms of the disease but also shows the neuroprotective property. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2023-09-11

    The potential clinical value of plasma biomarkers in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Plasma biomarkers could revolutionize many areas of the AD diagnostic pathway and care continuum, but further research is needed.

    Full summary, score breakdown and related studies → Original source

  10. 2023-09-11

    A Randomized Double-blind Study to Assess the Skin Irritation and Sensitization Potential of a Once-weekly Donepezil Transdermal Delivery System in Healthy Volunteers

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: Once-weekly 5-mg/d donepezil TDS demonstrated minimal skin irritation under conditions of use of 3 consecutive weekly patch applications to the same skin site and minimal sensitization potential. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2023-09-10

    Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Our results suggest that reactive astrogliosis, as indicated by different fluid biomarkers, influences the pathogenic cascade during the preclinical stage of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2023-09-09

    Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures

    ✓ Peer-reviewed Risk factors GeroScience

    Key finding: The aging population worldwide is facing a significant increase in age-related non-communicable diseases, including cardiovascular and brain pathologies. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2023-09-08

    Commentaries: Lecanemab: pioneering the way as the first approved drug for Alzheimer's disease treatment

    ✓ Peer-reviewed Clinical trials Inflammation research : official journal of the European Histamine Research Society ... [et al.]

    Key finding: Phase II trials revealed dose-dependent amyloid clearance and reduced clinical decline. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2023-09-08

    Multi-omic atlas of the parahippocampal gyrus in Alzheimer's disease

    ✓ Peer-reviewed Genetics Scientific data

    Key finding: Previous genetic studies have identified three main genes associated with early-onset familial Alzheimer's disease, however this subtype accounts for less than 5% of total cases.

    Full summary, score breakdown and related studies → Original source

  15. 2023-09-08

    A blood biomarker of accelerated aging in the body associates with worse structural integrity in the brain: replication across three cohorts

    ⚠ Preprint — not yet peer-reviewed Biomarkers medRxiv : the preprint server for health sciences

    Key finding: A novel epigenetic measure of biological aging, DunedinPACE, is associated with cognitive dysfunction, incident dementia, and mortality. +3 more findings

    Scored 23 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  16. 2023-09-08

    Long-term disgust habituation with limited generalisation in care home workers

    ✓ Peer-reviewed Health systems and care delivery Not indexed

    Key finding: Furthermore, we found that healthcare assistants showed no behavioural disgust avoidance on a web-based preferential looking task (equivalent to eye tracking). +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2023-09-07

    [Sleep and dementia]

    ✓ Peer-reviewed Risk factors Zeitschrift fur Gerontologie und Geriatrie

    Key finding: Aging is associated with changes in sleep structure and cerebral deposition of amyloid beta and tau proteins.

    Full summary, score breakdown and related studies → Original source

  18. 2023-09-07

    Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood

    ✓ Peer-reviewed Drug development Redox biology

    Key finding: These roles suggest that NRF2 and its directly associated proteins may be novel attractive therapeutic targets in the fight against AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2023-09-07

    Tryptamine: A privileged scaffold for the management of Alzheimer's disease

    ✓ Peer-reviewed Treatments Drug development research

    Key finding: Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative disease associated with aging.

    Full summary, score breakdown and related studies → Original source

  20. 2023-09-07

    Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial

    ✓ Peer-reviewed Biomarkers Nature medicine

    Key finding: Secondary cognitive and neuroimaging endpoints did not significantly differ from baseline to post-treatment further supporting a favorable safety profile.

    Full summary, score breakdown and related studies → Original source

  21. 2023-09-07

    Association between metabolic syndrome and risk of incident dementia in UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The association between metabolic syndrome (MetS) and incident dementia remains inconclusive. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2023-09-07

    Reminiscence and Digital Storytelling to Improve the Social and Emotional Well-Being of Older Adults With Alzheimer's Disease and Related Dementias: Protocol for a Mixed Methods Study Design and a Randomized Controlled Trial

    ✓ Peer-reviewed Treatments JMIR research protocols

    Key finding: Studies suggest that reminiscence strategies combined with an intergenerational approach may yield significant social and mental health benefits for participants. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2023-09-06

    Handicraft art leisure activities and cognitive reserve

    ✓ Peer-reviewed Risk factors The Clinical neuropsychologist

    Key finding: CR suggests that there are factors-most notably, educational attainment and occupational attainment-that can protect against the cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2023-09-06

    Artificial intelligence in the diagnosis of glaucoma and neurodegenerative diseases

    ✓ Peer-reviewed Brain scans and imaging Clinical & experimental optometry

    Key finding: The performance of published artificial intelligence methods varies due to several factors, yet the results suggest that such methods can potentially facilitate clinical diagnosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2023-09-06

    A neural mechanism of cognitive reserve: The case of bilingualism

    ✓ Peer-reviewed Brain scans and imaging NeuroImage

    Key finding: Bilingualism, and degree of second language proficiency specifically, were associated with lower gray matter integrity in a hub of the default mode network - a region that is particularly vulnerable to decline in aging and dementia - but preserved intrinsic functional network organization. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →