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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 5,751–5,775 of 27,380 studies, newest first · page 231 of 1096.

January 2025 25

  1. 2025-01-01

    Cuando el Alzheimer llega antes de lo esperado: la mutación del gen PSEN1

    ✓ Peer-reviewed Risk genes beyond APOE Con Evidencia

    Key finding: Studies in Jalisco have identified a mutation in the PSEN1 gene, associated with early-onset Alzheimer's.

    Full summary, score breakdown and related studies → Original source

  2. 2025-01-01

    A Novel Approach to the Prediction of Alzheimer’s Disease Progression by Leveraging Neural Processes and a Transformer Encoder Model

    ✓ Peer-reviewed Mild cognitive impairment IEEE Access

    Key finding: Alzheimer’s disease (AD) presents a significant global health challenge, necessitating accurate and early prediction methods for effective intervention and treatment planning. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-01-01

    Genetic drivers of hippocampal atrophy highlight the role of APOE functional variants and AD polygenicity in Mild Cognitive Impairment

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage Clinical

    Key finding: • Longitudinal imaging-genetics study of hippocampal atrophy trajectories over 5 years in ADNI. • APOE -ε4 carriership and ApoE CSF proteomic quantitative trait loci are key genetic drivers of accelerated hippocampal atrophy in amyloid-positive MCI. • Genetic effects are stage-specific, with strongest associations during the prodromal phase of AD. • Sex differences in atrophy rates are observed, but do not significantly alter genetic influences. • Findings support the utility of APOE and functional genetic markers as stratification tools for early neurodegeneration in AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2025-01-01

    Profiling characteristics of plasma exosomal miRNAs across cognitive stages: from normalcy to mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment RSC Advances

    Key finding: The results revealed distinct exosomal miRNA expression profiles across disease stages, with 10 conserved miRNAs showing progressive dysregulation along the NC-MCI-AD continuum. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2025-01-01

    Advancing Early Diagnosis: Predicting Mild Cognitive Impairment Progression in Normal Individuals Using Deep Learning on MRI Features

    ✓ Peer-reviewed Mild cognitive impairment IEEE Access

    Key finding: Each path includes advanced modules for feature refinement associated with the channel attention mechanism. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2025-01-01

    Amyloid‐related changes in fluency in patients with subjective cognitive decline

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    Key finding: Our results indicate that decline in semantic fluency is an early indicator of cognitive deficits in preclinical Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2025-01-01

    Aβ‐reactive T cell polyfunctionality response as a new biomarker for mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    Key finding: Amyloid‐reactive T cell polyfunctional response distinguishes MCI from normal aging and could serve as a novel MCI biomarker. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2025-01-01

    Neuropsychiatric symptoms in mild cognitive impairment and early Alzheimer's disease: Clinical pattern and diagnostic implications

    ✓ Peer-reviewed Mild cognitive impairment AIMS neuroscience

    Key finding: NPS affects up to 80% of individuals with early AD or MCI, often preceding cognitive decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2025-01-01

    Progression of clinical diagnostic features and cognitive decline in mild cognitive impairment with Lewy bodies

    ✓ Peer-reviewed Mild cognitive impairment Psychological Medicine

    Key finding: When an individual with MCI-LB endorsed more clinical features, they typically experienced a faster cognitive decline (ACE-R Score Difference β = -1.1 [-1.7 to -0.5]), specifically when experiencing visual hallucinations (β = -2.1 [-3.5 to -0.8]) or cognitive fluctuations (β = -3.4 [-4.8 to -2.1]).Individuals with MCI-LB typically acquired more clinical features with the passage of time (25.5% [20.0-32.0%] one-year probability), limiting the prognostic utility of baseline-only features. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2025-01-01

    Transcranial Direct Current Stimulation for Global Cognition in Mild Cognitive Impairment

    ✓ Peer-reviewed Mild cognitive impairment Chonnam Medical Journal

    Key finding: Mild cognitive impairment (MCI) is a condition characterized by noticeable deficits in memory retrieval or other cognitive domains than the individuals with the same age but do not significantly interfere with daily functioning. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2025-01-01

    A Multimodal Approach for Early Identification of Mild Cognitive Impairment and Alzheimer’s Disease With Fusion Network Using Eye Movements and Speech

    ✓ Peer-reviewed Mild cognitive impairment IEEE Transactions on Neural Systems and Rehabilitation Engineering

    Key finding: In this study, we analyzed a multimodal clinical eye-tracking and speech dataset collected from 78 participants (37 controls, 20 MCI, and 21 AD) during the King-Devick test and a reading task to classify and diagnose MCI/AD versus healthy controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-01-01

    Deep Learning-Based Framework for Predicting Mild Cognitive Impairment Progression in Neurology Using Longitudinal MRI

    ✓ Peer-reviewed Mild cognitive impairment IEEE Access

    Key finding: Comprehensive experiments conducted on the Alzheimer’s Disease ADNI dataset demonstrate the proposed model’s superior performance compared to state-of-the-art CNN and Transformer-based approaches, achieving an accuracy of 81.69%, recall of 80.27%, precision of 84.35%, and F1-score of 82.27%.

    Full summary, score breakdown and related studies → Original source

  13. 2025-01-01

    Event-related potential markers of subjective cognitive decline and mild cognitive impairment during a sustained visuo-attentive task

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage Clinical

    Key finding: In this study, we analysed event-related potentials (ERPs) recorded during a sustained visual attention task in a cohort of 178 individuals (119 SCD, 40 MCI, and 19 healthy subjects, HS) to investigate sensory and cognitive processing alterations associated with these conditions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2025-01-01

    Executive dysfunction relates to salience network desegregation in behavioural variant frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia NeuroImage Clinical

    Key finding: The organization of the brain into distinct networks increases (i.e., differentiation) during development and decreases (i.e., de-differentiation) during healthy aging, changes that are associated with improvements and worsening of cognition, respectively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2025-01-01

    Cerebrovascular co-pathology and cholinergic white matter pathways along the Lewy body continuum

    ✓ Peer-reviewed Lewy body dementia Brain Communications

    Key finding: Lewy body patients showed a significantly higher degree of WMSA in the external capsule cholinergic pathway despite no significant differences in global WMSA compared to controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2025-01-01

    Frontotemporal dementia characterization using neurite orientation dispersion and density imaging

    ✓ Peer-reviewed Lewy body dementia Brain Communications

    Key finding: GM ODI reduction exhibited a similar but more diffuse pattern compared with ICVF.

    Full summary, score breakdown and related studies → Original source

  17. 2025-01-01

    Multiplex connectomics reveal altered networks in frontotemporal dementia: A multisite study

    ✓ Peer-reviewed Lewy body dementia Network Neuroscience

    Key finding: A network neuroscience perspective can significantly advance the understanding of neurodegenerative disorders, particularly frontotemporal dementia (FTD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2025-01-01

    Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology

    ✓ Peer-reviewed Lewy body dementia Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    Key finding: Sex differences for clinicopathological correlations in LBD also occur at the regional pathology level. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-01-01

    Quantitative electroencephalography in the diagnosis of dementia with Lewy bodies

    ✓ Peer-reviewed Lewy body dementia Clinical Neurophysiology Practice

    Key finding: The spectral analysis of the resting-state eyes-closed electroencephalographic (rsEEG) activity typically shows abnormal delta (< 4 Hz), theta (4-7 Hz), and alpha (8-12 Hz) power in older patients with cognitive deficits due to progressive neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2025-01-01

    Clinical and neuropathological associations of plasma Aβ42/Aβ40, p‐tau217 and neurofilament light in sporadic frontotemporal dementia spectrum disorders

    ✓ Peer-reviewed Lewy body dementia Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    Key finding: Plasma p‐tau217 has clinical, neuroimaging, and neuropathological correlates in sporadic FTD and may identify FTD cases with AD co‐pathology.

    Full summary, score breakdown and related studies → Original source

  21. 2025-01-01

    Peripheral Single‐Cell Immune Characteristics Contribute to the Diagnosis of Alzheimer's Disease and Dementia With Lewy Bodies

    ✓ Peer-reviewed Lewy body dementia CNS Neuroscience & Therapeutics

    Key finding: These models demonstrated high diagnostic efficacy in distinguishing diseased samples from healthy donors as well as distinguishing AD and DLB cases. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2025-01-01

    Differentiating sporadic frontotemporal dementia from late-onset primary psychiatric disorders

    ✓ Peer-reviewed Lewy body dementia Brain Communications

    Key finding: Higher scores in cognitive screening [odds ratio (OR): 1.23], facial emotion processing (OR: 1.69), episodic memory (OR: 1.09), animal fluency (OR: 1.17), working memory (OR: 1.18), letter fluency (OR: 1.17) and depressive symptoms (OR: 7.41) were significantly associated with PPD (all Ps ≤ 0.010). +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2025-01-01

    Phase 2 study of palmitoylethanolamide combined with luteoline in frontotemporal dementia patients

    ✓ Peer-reviewed Lewy body dementia Brain Communications

    Key finding: In the last few years, co-ultramicronized palmitoylethanolamide combined with luteoline has emerged as a potential therapeutic molecule in neurodegenerative disorders pathogenically related to frontotemporal dementia, for its demonstrated strong anti-inflammatory and neuroprotective properties. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2025-01-01

    Striatal dopaminergic patterns and clinical features in frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia Brain Communications

    Key finding: Moreover, a theoretical model proposes that frontotemporal dementia manifestations result from a deficit in goal-directed behaviour, which may be related to altered dopamine control of the frontostriatal circuitry. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2025-01-01

    Modifiable risk factors and symptom progression in dementia over up to 8 years—Results of the DelpHi‐MV trial

    ✓ Peer-reviewed Risk factors Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

    Key finding: Higher education was associated with higher initial cognitive status but faster decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →