Newest studies

Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand

50/100 ✓ Peer-reviewed Risk factors International Journal of Geriatric Psychiatry

Key finding: Education, smoking, diabetes, depression, physical activity and social isolation were associated with a 1.13-1.55 times increased risk of dementia. +4 more findings

• Risk Factors
• Prevention
• Lifestyle

Full summary, score breakdown and related studies → Original source

Loneliness during the COVID-19 pandemic: A potential risk factor for post-pandemic cognitive decline in older adults without dementia

35/100 ✓ Peer-reviewed Risk factors Dementia & Neuropsychologia

Key finding: A total of eight studies were included from 1,384 search results, reviewing data from 10,449 cognitively unimpaired older adults. +4 more findings

• Risk Factors
• Lifestyle

Full summary, score breakdown and related studies → Original source

Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment

52/100 ✓ Peer-reviewed Risk factors Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring

Key finding: Of 4930 participants, 2052 (41%) had MCI. +4 more findings

• Lifestyle
• Early Stage

Full summary, score breakdown and related studies → Original source

Burden and risk factors of Alzheimer's disease and other dementias in Vietnam from 1990 to 2021 – A comprehensive analysis from global burden disease

45/100 ✓ Peer-reviewed Risk factors Cerebral Circulation - Cognition and Behavior

Key finding: In 2021, the ASRs for AD and other dementias incidence and prevalence in Vietnam were 110.09 (95 % UI: 96.21-126.57) and 649.42 (95 % UI: 556.89-744.39) per 100,000 persons which were comparable to those in the Southeast Asia region and globally, with the burden predominantly observed in individuals aged 65 and older. +4 more findings

• Risk Factors

Full summary, score breakdown and related studies → Original source

Vascular risk factor associations with subjective cognitive decline and mild behavioural impairment

48/100 ✓ Peer-reviewed Risk factors Brain Communications

Key finding: Having three or more vascular risk factors (odds ratio = 1.23, 95% confidence interval [1.04-1.47]), actively smoking (odds ratio = 1.54, 95% confidence interval [1.29-1.82]), being overweight (odds ratio = 1.46, 95% confidence interval [1.22-1.74]), and having diabetes (odds ratio = 1.29, 95% confidence interval [1.09-1.53]) were associated with higher odds of subjective cognitive decline. +1 more finding

• Risk Factors
• Early Stage

Full summary, score breakdown and related studies → Original source

Face Mesh for Dementia Detection: Evaluating Data Augmentation in Deep Learning and Traditional Machine Learning

34/100 ✓ Peer-reviewed Digital health tools IEEE Access

Key finding: Early screening and intervention have demonstrated efficacy for both current and prospective treatments. +1 more finding

• Digital Tools

Full summary, score breakdown and related studies → Original source

Alpha-synuclein aggregation induces prominent cellular lipid changes as revealed by Raman spectroscopy and machine learning analysis

41/100 ✓ Peer-reviewed Digital health tools Brain Communications

Key finding: HEK293, Neuro2a and SH-SY5Y expressing increased levels of α-synuclein were treated with sonicated α-synuclein pre-formed fibrils, to model seeded aggregation.

• Digital Tools
• Other Dementias

Full summary, score breakdown and related studies → Original source

Reimagining dementia screening: A stakeholder-informed perspective on artificial intelligence, digital biomarkers, and real-world implementation

33/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer s Disease Reports

Key finding: The approval of disease-modifying treatments for Alzheimer's disease demands a rethinking of cognitive screening. +3 more findings

• Digital Tools
• Diagnosis
• Biomarkers

Full summary, score breakdown and related studies → Original source

Agentic artificial intelligence in cognitive screening: A translational roadmap for dementia care

33/100 ✓ Peer-reviewed Digital health tools Journal of Alzheimer s Disease Reports

Key finding: Yet decline is dynamic, shaped by environment, comorbidities, and life history. +4 more findings

• Digital Tools
• Diagnosis

Full summary, score breakdown and related studies → Original source

Electroencephalogram and Event-Related Potential in Mild Cognitive Impairment: Recent Developments in Signal Processing, Machine Learning, and Deep Learning

43/100 ✓ Peer-reviewed Digital health tools IEEE Journal of Selected Areas in Sensors

Key finding: Mild cognitive impairment (MCI) is an early stage of non-age-related cognitive decline with an increased risk of progressing to dementia. +3 more findings

• Digital Tools
• Early Stage

Full summary, score breakdown and related studies → Original source

Exploring the Effectiveness of Machine Learning and Deep Learning Techniques for EEG Signal Classification in Neurological Disorders

51/100 ✓ Peer-reviewed Digital health tools IEEE Access

Key finding: These features are stored in an offline database for easy access during analysis, to be then applied for both ML and DL models, systematically testing their performance and comparing the results to prior studies. +3 more findings

• Digital Tools

Full summary, score breakdown and related studies → Original source

Artificial intelligence for medicine 2025: Navigating the endless frontier

39/100 ✓ Peer-reviewed Digital health tools The Innovation Medicine

Key finding: By integrating clinical information, pathology, medical imaging, physiological signals, and omics data, AI significantly enhances the precision of research into disease mechanisms and patient prognoses.

• Digital Tools

Full summary, score breakdown and related studies → Original source

Psoriasis and dementia: A population‐based matched cohort study of adults in England

50/100 ✓ Peer-reviewed How common it is Annals of Clinical and Translational Neurology

Key finding: Among 360,014 individuals with psoriasis and 1,799,617 without, psoriasis was associated with a small increased risk of all-cause dementia (adjusted hazard ratio [aHR] 1.06, 95% CI 1.04-1.08; absolute rate difference 24 per 100,000 person-years). +4 more findings

Full summary, score breakdown and related studies → Original source

Cognitive reserve and its impact on cognitive and functional abilities, physical activity and quality of life following a diagnosis of dementia: longitudinal findings from the Improving the experience of Dementia and Enhancing Active Life (IDEAL) study

60/100 ✓ Peer-reviewed How common it is Age and Ageing

Key finding: Higher cognitive reserve was associated with better cognition, fewer functional difficulties, more physical activity and better quality of life at baseline but was associated with accelerated cognitive decline and greater dependence over time. +3 more findings

• Lifestyle

Full summary, score breakdown and related studies → Original source

Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study

49/100 ✓ Peer-reviewed How common it is BMJ Open Diabetes Research & Care

Key finding: Among a cohort of 118 006 individuals, the incident rate (IR) of dementia was 0.56/1000 person-years over a median follow-up period of 1.54 years among SGLT-2i users compared with 2.67/1000 person-years in DPP-4i users, over a median follow-up period of 1.79 years. +3 more findings

• Risk Factors

Full summary, score breakdown and related studies → Original source

Birth Rate as a Determinant of Dementia Incidence: A Comprehensive Global Analysis

35/100 ✓ Peer-reviewed How common it is American Journal of Alzheimer s Disease & Other Dementias®

Key finding: Lower birth rate is an independent risk factor for dementia, particularly in developed countries. +4 more findings

• Risk Factors

Full summary, score breakdown and related studies → Original source

Trajectory of Cardiogenic Dementia: A New Perspective

44/100 ✓ Peer-reviewed How common it is Journal of Cellular and Molecular Medicine

Key finding: In addition, coronary artery disease (CAD) is also associated with the development of cognitive impairment. +1 more finding

Full summary, score breakdown and related studies → Original source

Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT

52/100 ✓ Peer-reviewed How common it is Kidney Medicine

Key finding: Adjudicated AKI, which was largely mild and reversible, was independently associated with increased risk of probable dementia and the composite of probable dementia and MCI in older adults at high cardiovascular risk. +4 more findings

• Early Stage
• Risk Factors

Full summary, score breakdown and related studies → Original source

Unraveling the role of proteins in dementia: insights from two UK cohorts with causal evidence

61/100 ✓ Peer-reviewed How common it is Brain Communications

Key finding: NEFL (hazard ratio [HR] [95% confidence intervals (CIs)]: 1.54 [1.29, 1.84]) and RPS6KB1 (HR [95% CI]: 1.33 [1.16, 1.52]) were robustly associated with incident all-cause dementia; MMP12 (HR [95% CI]: 2.06 [1.41, 2.99]) was associated with vascular dementia in ELSA, after correcting for multiple testing. +2 more findings

Full summary, score breakdown and related studies → Original source

Virtual Data Collection Strategies in Research on Alzheimer’s Disease and Related Dementias (ADRD)

49/100 ✓ Peer-reviewed Disparities Innovation in Aging

Key finding: Virtual data collection was highly feasible in both studies, successfully engaging participants in ADRD research, including those from underrepresented racial and ethnic groups. +4 more findings

• Health Equity

Full summary, score breakdown and related studies → Original source

Global patterns linking total meat supply to dementia incidence: A population-based ecological study

36/100 ✓ Peer-reviewed Disparities AIMS neuroscience

Key finding: While aging remains the primary risk factor, emerging evidence suggests that diet, including total meat supply, may influence dementia risk. +3 more findings

• Risk Factors
• Health Equity
• Lifestyle

Full summary, score breakdown and related studies → Original source

The deprivation cascade hypothesis of dementia

33/100 ✓ Peer-reviewed Disparities Aging and Health Research

Key finding: There are significant disparities in dementia risk and care burden in the global population.

Full summary, score breakdown and related studies → Original source

Risk factors and gender disparity of cognitive impairment among cancer and neurological diseases regarding rural West Texas

29/100 ✓ Peer-reviewed Disparities Journal of Alzheimer s Disease Reports

Key finding: Individuals aged 70 and above experiencing memory loss in Cochran and Parmer Counties had a statistically significant association with cognitive impairment (p < 0.001). +4 more findings

• Health Equity
• Risk Factors

Full summary, score breakdown and related studies → Original source

Resilience in Black/African American Partner Caregivers of Persons With Alzheimer's Disease and Related Dementias

37/100 ✓ Peer-reviewed Disparities Research in Gerontological Nursing

Key finding: Four major themes emerged: Unfolding Process of ADRD Discovery , Resilience is Multifaceted in Caregiving , Resilience is an Adaptive Process , and Cultural Heritage Shapes Caregivers' Resilience Experiences .

• Health Equity
• Caregiving

Full summary, score breakdown and related studies → Original source

Informing etiological heterogeneity of mild cognitive impairment and risk for progression to dementia with plasma p-tau217

55/100 ✓ Peer-reviewed Disparities The Journal of Prevention of Alzheimer s Disease

Key finding: Longitudinally, older age (OR=1.14 [1.06-1.22], p<.001), higher levels of p-tau217 (OR=10.37 [3.00-35.02], p<.001) and higher neuropsychiatric symptoms (OR=1.19 [1.02-1.39], p=.023) were associated with higher odds of progression to dementia. +4 more findings

• Biomarkers
• Early Stage

Full summary, score breakdown and related studies → Original source