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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 5,726–5,750 of 27,380 studies, newest first · page 230 of 1096.

January 2025 25

  1. 2025-01-01

    Treatment-resistant patients with focal epilepsy of unknown cause display reduced neurogranin levels: a preliminary study

    ✓ Peer-reviewed Disease mechanisms Ideggyógyászati Szemle

    Key finding: Neurogranin levels were significantly reduced in MTLE-HS patients as compared to FLE patients and healthy controls but were not correlated with any of the clinical and cognitive variables. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2025-01-01

    Comprehensive metabolomics profiling reveals novel biomarkers and pathways for early detection of Alzheimer’s disease

    ✓ Peer-reviewed Disease mechanisms Brain Communications

    Key finding: Clinical Dementia Rating-Global scores (1.44 ± 0.65 versus 0.24 ± 0.25; P < 0.0001) and Patient Health Questionnaire-9 scores (4.88 ± 4.21 versus 0.20 ± 0.50; P < 0.0001) were higher than controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2025-01-01

    Neurobiology of dementia

    ✓ Peer-reviewed Disease mechanisms World Family Medicine Journal/Middle East Journal of Family Medicine

    Key finding: At the microscopic level, neuro-inflammation, mitochondrial dysfunction, oxidative stress, excitotoxicity, impaired protein clearance, and synaptic loss converge to promote neuronal injury. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2025-01-01

    Plasma vesicle-associated membrane protein 2 and glial fibrillary acidic protein associate with synaptic density in older adults without dementia

    ✓ Peer-reviewed Disease mechanisms Brain Communications

    Key finding: The study population demonstrated limited PET-based amyloid-β and tau pathology, which did not associate with any of the investigated plasma biomarkers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2025-01-01

    Selective association of EEG microstates with clinical symptoms and mutation status in monogenic Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms NeuroImage Clinical

    Key finding: EEG microstates are transient and short-lasting periods of stable scalp potential fields that are associated with disturbed temporal dynamics of large-scale brain networks, affected by early synaptic loss in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-01-01

    Layer-Specific Colocalization of Microglia with Amyloid Plaques in the Middle Temporal Gyrus Predicts Cognitive Decline in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Aging and Disease

    Key finding: Aβ and PAM were significantly higher in AD, with no sex- or layer-specific differences. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2025-01-01

    Traumatic Brain Injury and Dementia: Mechanisms, Risk Stratification, and Clinical Management

    ✓ Peer-reviewed Inflammation and the immune system Journal of Clinical Neurology

    Key finding: Traumatic brain injury (TBI) is one of the main mechanisms underlying health issues associated with functional and structural brain changes.

    Full summary, score breakdown and related studies → Original source

  8. 2025-01-01

    Neuroinflammation and Cognitive health in Type 2 Diabetes

    ✓ Peer-reviewed Inflammation and the immune system Medical Research Archives

    Key finding: There is increasing awareness that cognitive impairment, which can range from mild difficulties to severe dementia, is a significant complication associated with T2D. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2025-01-01

    Serum neurofilament light is superior to glial fibrillary acidic protein to distinguish sporadic frontotemporal dementia from late-onset primary psychiatric disorders: a retrospective DIPPA-FTD study

    ✓ Peer-reviewed Brain tissue and pathology BMJ Neurology Open

    Key finding: Significantly higher serum median NfL and GFAP levels were found in sporadic bvFTD (NfL 33.3 pg/mL, IQR (19.6-49.6); GFAP 124.5 pg/mL, IQR (83.5-181.6)) compared with PPD (NfL 12.2 pg/mL, IQR (9.8-17.9); GFAP 68.9 pg/mL, IQR (50.6-95.0), both p<0.001). +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2025-01-01

    New VSED Advance Directive: Improved Documentation to Avoid Late-Stage Dementia

    ✓ Peer-reviewed Brain tissue and pathology The Journal of Law Medicine & Ethics

    Key finding: Second, we identify the disadvantages of another option for accomplishing the goal of not living into advanced dementia, preemptive VSED. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2025-01-01

    Psychosocial burdens in early- versus late-onset dementia: analysis of discrimination, stress, and loneliness in the All of Us Research Program

    ✓ Peer-reviewed Brain tissue and pathology Innovation in Aging

    Key finding: EOD participants reported the highest mean levels of all psychosocial outcomes (e.g., everyday discrimination score of 8.3 in EOD vs 4.6 in LOD and 6.8 in no-dementia). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-01-01

    Late-onset dementia with leukoencephalopathy and a COL4A2 gene variant, causal link or fortuitous association: a case report

    ✓ Peer-reviewed Brain tissue and pathology Cerebral Circulation - Cognition and Behavior

    Key finding: Cerebral small vessel disease can manifest as vascular dementia, typically associated with vascular risk factors or cerebral amyloid angiopathy, and more rarely associated with hereditary conditions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2025-01-01

    The lifetime accumulation of multimorbidity and its influence on dementia risk: a UK Biobank study

    ✓ Peer-reviewed Long-term cohort studies Brain Communications

    Key finding: We observed that the odds of developing dementia varied based on when these comorbidities were diagnosed. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2025-01-01

    Effect of comprehensive nursing interventions on psychological well-being and treatment adherence in dementia patients

    ✓ Peer-reviewed Cognitive tests and assessment American Journal of Translational Research

    Key finding: The observation group had significantly lower Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores than the control group (both P<0.001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2025-01-01

    ApoE Genotype, Age, and Cognitive Decline in Old Chinese Individuals Without Dementia: A Population‐Based Study With Five‐Year Follow‐Up

    ✓ Peer-reviewed Cognitive tests and assessment International Journal of Geriatric Psychiatry

    Key finding: After 5 years, 666 (86.8%) individuals were followed up. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2025-01-01

    The association between the severity of cognitive impairment and the risk of falls in patients with dementia

    ✓ Peer-reviewed Cognitive tests and assessment Family Medicine & Primary Care Review

    Key finding: Our findings indicate that the severity of cognitive impairment was significantly associated with an increased risk of falls in patients with dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2025-01-01

    Cognitive Impairment Screening Test in Korea as a Screening Tool for Dementia: The Correlation Study of Subtest Scores With Korean Version of the Mini Mental State Examination 2nd Edition

    ✓ Peer-reviewed Cognitive tests and assessment Dementia and Neurocognitive Disorders

    Key finding: Multivariate correlation analysis, which was adjusted for age, sex, and education level, revealed a significant correlation between the two tests in orientation, memory, and attention. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2025-01-01

    Cognitive trajectories and dementia risk in patients with schizophrenia spectrum versus affective disorders

    ✓ Peer-reviewed Cognitive tests and assessment Psychological Medicine

    Key finding: = 1,217; 65.0 years) showed earlier initial MMSE scores (by 6.1 years, 95% CI = 5.2-7.0), earlier dementia diagnoses (by 2.3 years, 95% CI = 0.9-3.7) but lower dementia risk (adjusted HR = 0.81; 95% CI = 0.69-0.95). +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-01-01

    Statins, cholesterol and cognition at the time of Alzheimer's disease diagnosis: A cross-sectional study from the Swedish registry for cognitive/dementia disorders

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer s Disease Reports

    Key finding: We included 3074 AD patients (mean age 78.1 years; 59.4% women), of whom 1028 used statins (79.6% simvastatin, 20.4% atorvastatin). +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2025-01-01

    Comparing Traditional and Technology-Based Methods for Executive Function and Attention Training in Moderate Alzheimer's Dementia

    ✓ Peer-reviewed Cognitive tests and assessment Psicothema

    Key finding: The interventions proved effective in improving executive functions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2025-01-01

    Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders

    ✓ Peer-reviewed Risk genes beyond APOE Figshare

    Key finding: The unique spatial and functional demands of neurons result in differences in the regulation of metabolic, autophagic, mitophagic and biosynthetic processes compared to other cell types.

    Full summary, score breakdown and related studies → Original source

  22. 2025-01-01

    Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders

    ✓ Peer-reviewed Risk genes beyond APOE Figshare

    Key finding: The unique spatial and functional demands of neurons result in differences in the regulation of metabolic, autophagic, mitophagic and biosynthetic processes compared to other cell types.

    Full summary, score breakdown and related studies → Original source

  23. 2025-01-01

    Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells

    ✓ Peer-reviewed Risk genes beyond APOE Figshare

    Key finding: We previously showed that chronic stress impairs adult hippocampal neurogenesis by triggering autophagic cell death of adult hippocampal neural stem (HCN) cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2025-01-01

    Presenilin 2 regulates corticosterone-induced autophagic death of adult hippocampal neural stem cells

    ✓ Peer-reviewed Risk genes beyond APOE Figshare

    Key finding: We previously showed that chronic stress impairs adult hippocampal neurogenesis by triggering autophagic cell death of adult hippocampal neural stem (HCN) cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2025-01-01

    Genetic association of ABCA7 and PSEN1 polymorphisms with Alzheimer’s disease in the northeast Algerian population: Exploring risk factors

    ✓ Peer-reviewed Risk genes beyond APOE Archives of Biological Sciences

    Key finding: Significant associations were observed between ABCA7 rs3764650 and AD under dominant and additive models. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →