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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 5,151–5,175 of 27,380 studies, newest first · page 207 of 1096.

February 2025 25

  1. 2025-02-24

    Towards a better diagnosis and treatment of dementia: Identifying common and distinct neuropathological mechanisms in Alzheimer's and vascular dementia

    ✓ Peer-reviewed Getting a diagnosis Neurobiology of Disease

    Key finding: While in AD, the improved understanding of Amyloid beta (Aß) mismetabolism and tau hyperphosphorylation as pathophysiological hallmarks has led to significant clinical breakthroughs, similar advances in VaD are lacking.

    Full summary, score breakdown and related studies → Original source

  2. 2025-02-24

    SMART technologies that influence construction health and safety factors risk reduction in the current digital era

    ✓ Peer-reviewed Prevention and risk Smart and Sustainable Built Environment

    Key finding: Further, the paper discusses ST’s connectivity, which would aid the organization’s overall H&S management.

    Full summary, score breakdown and related studies → Original source

  3. 2025-02-24

    Updates on vascular dementia

    ✓ Peer-reviewed Prevention and risk Stroke and Vascular Neurology

    Key finding: The clinical features overlapping between AD and VaD create significant challenges for physicians.

    Full summary, score breakdown and related studies → Original source

  4. 2025-02-23

    Small-Molecule Inhibitors of Amyloid Beta: Insights from Molecular Dynamics—Part A: Endogenous Compounds and Repurposed Drugs

    ✓ Peer-reviewed Disease mechanisms Pharmaceuticals

    Key finding: The amyloid hypothesis is the predominant model of Alzheimer's disease (AD) pathogenesis, suggesting that amyloid beta (Aβ) peptide is the primary driver of neurotoxicity and a cascade of pathological events in the central nervous system.

    Full summary, score breakdown and related studies → Original source

  5. 2025-02-23

    Modifiable Lifestyle Risk Factors and Strategies for Slowing the Progression of Age-Related Macular Degeneration

    ✓ Peer-reviewed Prevention and risk Vision

    Key finding: Smoking (current and former), physical inactivity, prolonged sunlight exposure, as well as conditions such as diabetes, hypertension, cardiovascular disease, and obesity have all been associated with an increased risk of early AMD and its progression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-02-23

    Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk

    ✓ Peer-reviewed Prevention and risk Nutrients

    Key finding: The bioactive compounds that are enriched in these nutrition patterns and able to manage dyslipidemia include monounsaturated fatty acids such as ω-3, polyphenols such as oleuropein, resveratrol, flavonoids, and catechins, carotenoids, phytosterols and soluble and unsoluble fibers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2025-02-22

    Supportive Interventions Involving Family Carers of Patients With Delirium Superimposed on Dementia in Hospital: A Scoping Review

    ✓ Peer-reviewed Clinical safety International Journal of Older People Nursing

    Key finding: Studies focused on educational and system change to improve the care of people with DSD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2025-02-22

    Altered spatiotemporal brain dynamics of interoception in behavioural-variant frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia EBioMedicine

    Key finding: In bvFTD patients, longer interoceptive-ACWs than controls were observed in the bilateral fronto-temporal and parietal regions. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2025-02-22

    Identification of UBE2N as a biomarker of Alzheimer’s disease by combining WGCNA with machine learning algorithms

    ✓ Peer-reviewed Digital health tools Scientific Reports

    Key finding: Functional enrichment analysis revealed that UBE2N is associated with synaptic vesicle cycling and T cell/B cell receptor signaling pathways. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2025-02-21

    The digitalization of psychopathology: 'TV sign' and 'Smartphone sign' as red flags for dementia

    ✓ Peer-reviewed Cognitive tests and assessment Neurocase

    Key finding: Moreover, the treatment outcome in terms of cognition and behavior on low doses of Risperidone and Escitalopram shows promising results and paves the way for the treatment of other DMS.

    Full summary, score breakdown and related studies → Original source

  11. 2025-02-21

    Associations between stroke and vascular dementia combing Mendelian randomization with network pharmacology

    ✓ Peer-reviewed Vascular contributions Medicine

    Key finding: The results of the inverse variance weighted analysis demonstrate a significant positive causal relationship between stroke and VaD (OR = 2.06, 95% confidence interval [CI] = 1.17-3.61, P = .01). +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-02-21

    The efficacy of computerized cognitive training in patients with coronary heart disease and cognitive impairment, no dementia: study protocol for a randomized controlled trial

    ✓ Peer-reviewed Prevention trials Trials

    Key finding: COG-T CHD is the first clinical trial to evaluate the efficacy of computer-based cognitive training in patients with coronary heart disease, filling an important gap in the treatment evidence for cognitive digital therapy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2025-02-21

    Transgenic iPSC Lines with Genetically Encoded MitoTimer to Study Mitochondrial Biogenesis in Dopaminergic Neurons with Tauopathy

    ✓ Peer-reviewed Disease mechanisms Biomedicines

    Key finding: Transgenic iPSC lines provide a unique tool to study the molecular and genetic mechanisms of FTDP-17 caused by the presence of the c.2013T > G (p.N279K) mutation, as well as to test potential drugs in vitro.

    Full summary, score breakdown and related studies → Original source

  14. 2025-02-21

    SUMO2/3 conjugation of TDP-43 protects against aggregation

    ✓ Peer-reviewed Brain tissue and pathology Science Advances

    Key finding: We conclude that SUMO2/3 protein conjugation is a cellular mechanism to stabilize cytosolic RNA-free TDP-43 against aggregation.

    Full summary, score breakdown and related studies → Original source

  15. 2025-02-21

    Investigating Modifiable Factors Associated with Cognitive Decline: Insights from the UK Biobank

    ✓ Peer-reviewed Long-term cohort studies Biomedicines

    Key finding: Our findings revealed a significant impact of unfavorable medical and psychiatric histories on processing speed and visual episodic memory decline (Hazard Ratio (HR) = 1.34, 95% CI: 1.20–1.51, p = 6.06 × 10⁻7; HR = 1.50, 95% CI: 1.22–1.86, p = 1.62 × 10⁻4, respectively). +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2025-02-21

    Increased risk of dementia in patients with primary Sjogren’s syndrome: a nationwide population-based cohort study

    ✓ Peer-reviewed How common it is The Korean Journal of Internal Medicine

    Key finding: The incidence of dementia was 0.68 (95% CI 0.64-0.72) cases per 100 person-years in pSS, and it was 0.58 (0.56-0.60) in the controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2025-02-21

    “Diagnose & Adios”: Multi-Perspective Insights on Formal Service Use in Dementia Family Caregivers

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Three overarching concepts were identified: "Pathways to Preparedness'", 'Multi-Level Barriers', and 'Bridging the Gap.' +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2025-02-21

    Identifying the needs of natural caregivers caring for a person with dementia: a mixed method study

    ✓ Peer-reviewed Caregiving BMC Family Practice

    Key finding: A total of 199 general practitioners and 67 caregivers participated in the quantitative study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-02-21

    Incidence trends of early-onset breast cancer by lifestyle risk factors

    ✓ Peer-reviewed Prevention and risk BMC Cancer

    Key finding: The highest annual increase in age-standardized incidence was observed among women aged 40-49 who were overweight (AAPC 4.0%, 95% CI 0.5-7.7%), currently smoking (AAPC 3.3%, 95% CI 0.1-6.6%) or moderately physically active (AAPC 2.9%, 95% CI 0.3-5.6%). +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2025-02-21

    A Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

    ✓ Peer-reviewed Prevention and risk Critical Care Medicine

    Key finding: The task force issued five statements related to the management of anxiety, agitation/sedation, delirium, immobility, and sleep disruption in adults admitted to the ICU. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2025-02-21

    Mediterranean diet: Why a new pyramid? An updated representation of the traditional Mediterranean diet by the Italian Society of Human Nutrition (SINU)

    ✓ Peer-reviewed Prevention and risk Nutrition Metabolism and Cardiovascular Diseases

    Key finding: In recent decades, an increasing body of research has highlighted significant scientific evidence linking adherence to the Mediterranean diet with a reduced risk of chronic diseases.

    Full summary, score breakdown and related studies → Original source

  22. 2025-02-21

    Identification and catalog of viral transcriptional regulators in human diseases

    ✓ Peer-reviewed Genetics iScience

    Key finding: Prioritized Epstein-Barr virus (EBV) vTR target genes were associated with multiple sclerosis (MS), rheumatoid arthritis, and systemic lupus erythematosus. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2025-02-21

    Outcomes for Dual-Eligible Beneficiaries With Dementia in Special Needs Plans and Other Medicare Advantage Plans

    ✓ Peer-reviewed Health systems and care delivery JAMA Network Open

    Key finding: Analysis included a total of 121 145 patients in non-D-SNP plans with an enrollment of 173 662 patient-years (mean [SD] age, 81.8 [7.8] years; 122 565 female [70.6%]; 6078 Asian [3.5%], 34 150 Black [19.7%], 37 580 Hispanic [21.6%], 95 854 White [55.2%]) and 78 166 patients in D-SNP plans with an enrollment of 122 681 patient-years (mean [SD] age, 80.2 [8.0] years; 87 329 female [71.2%]; 10 530 Asian [8.6%], 33 280 Black [27.1%], 43 294 Hispanic [35.3%], 35 577 White [29.0%]). +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2025-02-21

    Early Alzheimer's Disease with frequent neuritic plaques harbors neocortical tau seeds distinct from primary age-related tauopathy

    ✓ Peer-reviewed Laboratory science Nature Communications

    Key finding: This may suggest that not all tau species are equally pathogenic and raises the question of whether unidentified tau modifications augment tau seeding activity and neurodegeneration in AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2025-02-20

    Harmonizing HTA Evidence Needs and Expectations: Challenges and Opportunities to Improve Evidence Generation, Ensure Access and Affordability

    ✓ Peer-reviewed Health systems and care delivery Clinical pharmacology and therapeutics

    Key finding: The article concludes by offering some potential policy solutions that can meet the goals of robust evidence generation, patient access, and system affordability, including reimbursement with evidence development, outcomes-based contracts, and other types of managed entry agreements.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →