Each study has a usefulness score out of 100 (rubric version 4.0). Tap a score to see what makes it up.
Highest usefulness score first. Studies without a score come last.
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Research suggests that social, physical, and cognitively challenging activities during lifetime, could mitigate the negative effects of aging on cognitive function.
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Cerebral small vessel disease (CSVD) is the most common, chronic and progressive vascular disease.
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40/100
The American Society for Parenteral and Enteral Nutrition (ASPEN) Position Paper focus is on applying the 4 ethical principles for clinician's decision-making in the use of artificially administered nutrition and hydration (AANH) for adult and pediatric patients.
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Formation of biomolecular condensates through liquid-liquid phase separation (LLPS) has emerged as a pervasive principle in cell biology, allowing compartmentalization and spatiotemporal regulation of dynamic cellular processes.
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We study the impact of grocery-store density on the food waste generated at stores and by households.
Why it matters
This modeling study found that higher grocery store density reduces food waste up to a threshold density, beyond which waste increases. It has no relevance to treating, curing, or preventing Alzheimer's disease.
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However, individuals participating in training regimens differ greatly with respect to their outcomes, demonstrating the importance of considering individual differences, in particular age and baseline performance in a cognitive domain, when evaluating the effectiveness of cognitive training.
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Human evolution has regularly intersected with technology.
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Even among patients with early cognitive impairment seen in specialty clinics and their caregivers, most were unaware of the decisions they could face, and there were many barriers to planning for these decisions.
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This qualitative study about the experiences and perceptions of family carers of people with a chronic life-limiting illness living at home regarding the collaboration with different healthcare providers in the last phase life, showed that family carers experience a lot of possibilities, but perceive missed opportunities as well, for healthcare professionals to effectively collaborate with them for palliative care.
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Women are more prone than men to develop age-related dementia, such as Alzheimer's disease (AD).
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40/100
After accounting for individual and county level covariates, we found that a 10 percentage‐point increase in HCBS breadth among individuals with ADRD was associated with 1.1 percentage point reduction (P < 0.01) in the likelihood of NH placement.
Why it matters
This study found that greater breadth of Medicaid home- and community-based services was linked to a lower likelihood of nursing home placement among people with Alzheimer's disease and related dementias. It does not test any treatment, cure or prevention, but examines how long-term care policy may affect where people live.
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ACP practices are evolving.
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Quantitative electroencephalography (QEEG) is a modern type of electroencephalography (EEG) analysis that involves recording digital EEG signals which are processed, transformed, and analyzed using complex mathematical algorithms.
Why it matters
This review concludes that quantitative EEG is not meant to pinpoint an immediate diagnosis but to provide additional insight alongside other diagnostic evaluations for precise diagnosis, severity assessment, and treatment response evaluation. It reports nothing about treating, curing, or preventing Alzheimer's disease.
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Prior research suggests that both exergaming and virtual reality (VR)-based training programs could improve executive functions in older adults.
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Despite the increasing national attention being given to the risks posed by unidentified and untreated hearing loss, stakeholders—including primary care physicians, caregivers, and patients—have yet to make any significant progress in improving earlier recognition of hearing loss.
Why it matters
This article states that stakeholders have not made significant progress in improving earlier recognition of hearing loss despite growing attention to its risks. It recommends measuring outcomes such as quality of life, function, depression, cognitive status, falls history, and social isolation in hearing intervention research.
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The verbal fluency task (VFT) is a well-established cognitive marker for mild cognitive impairment (MCI) in the prodromal stage of Alzheimer´s dementia (AD).
Why it matters
This study found a decreased hemodynamic response in the inferior frontotemporal cortex during a verbal fluency task in people with mild cognitive impairment, suggesting it could serve as a diagnostic biomarker. It is about diagnosis and does not report any treatment, cure, or prevention.
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Compared with “well-nourished,” “malnourished” PWD had 3-4 times the hazard of severe dementia [hazard ratio (HR), 4.31; P =0.014] and death (HR, 3.04; P <0.001).
Why it matters
This study found that people with dementia who were malnourished had a higher risk of severe dementia and death than those who were well-nourished. It does not test a treatment or cure, but it suggests that nutritional status may be a target for intervention in dementia care.
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PVTs provide valuable information regarding response bias and, under the right circumstances, can provide excellent evidence of response bias.
Why it matters
This review gives guidance on using performance validity tests to detect biased or invalid test responses, and warns that results must be interpreted cautiously in people with dementia, low intelligence, limited English, minority cultural background, or low education. It concerns how cognitive test results are judged, not how Alzheimer's disease is treated, cured, or prevented.
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At present there is a rapid growth of aging population groups worldwide, which brings about serious economic and social problems.
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Of the 8688 individuals in the Medicare Advantage population with a dementia diagnosis, 1061 (12.2%) received an antipsychotic medication.
Why it matters
This study describes how many older Medicare Advantage patients with dementia received antipsychotic medications and what factors were associated with that use. It does not test any treatment, cure, or prevention for Alzheimer's disease, and it suggests care management programs could help limit inappropriate antipsychotic use.
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It has been shown that cognitive training (CogTr) is effective and recuperative for older adults, and can be used to fight against cognitive decline.
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Four broad areas were identified as requiring complex decisions at the end of life; 1) eating/swallowing difficulties, 2) agitation/restlessness, 3) ending life-sustaining treatment, and 4) providing "routine care" at the end of life.
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When planning an improvement project in PC, services should pay particular attention to factors associated with their chosen implementation strategy.
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SPLS outperformed PLS, finding statistically significant effects and providing higher correlation values in hold-out data.
Why it matters
This paper describes a new statistical framework for finding relationships between brain scans and clinical test items in people with various degrees of dementia, and it found two significant associations between brain voxels and questions from a cognitive test. It is a methods paper about analysis techniques, not about treating, curing or preventing Alzheimer's disease.
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40/100
Despite the rapidly ageing population and a predicted sevenfold increase in the prevalence of dementia in minority ethnic communities, people from these communities remain under-represented in specialist dementia services.
Why it matters
This scoping exercise explored perceptions of dementia and use of services in British Indian, African and Caribbean, and East and Central European communities in the UK. It found that although groups attributed a biological basis for memory loss, misconceptions about the cause of dementia prevailed, and some used religion rather than medical services for control.
From across this topic
10 of the 7,967 studies in this topic, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Would older adults with mild cognitive impairment adhere to and benefit from a structured lifestyle activity intervention to enhance cognition?: a cluster randomized controlled trial
- Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis
- Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging
- Cluster Analysis of Palliative Care Patients’ Trajectories in Primary Care: Hospitalization Yes, but Home and Nursing Home Care Above All
- Survival Variations Based on Hospice Qualifying Condition: A Retrospective Review
- Race-Specific Dementia Risk Prediction Using 2024 Lancet Commission Risk Factors and Resting Heart Rate: A Survival Analysis of 55,004 NACC Participants
- The diagnosis of young-onset dementia
- Strengths and support of older people affected by precarity in South Louisiana
- The 3-Minute Diagnostic Confusion Assessment Method severity score correlates with the Delirium Rating Scale–Revised–98 and with biomarkers of delirium
- Computerized and virtual reality cognitive training for individuals at high risk of cognitive decline: systematic review of the literature